These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. The dihydrofolate reductase-thymidylate synthetase gene in the drug resistance of malaria parasites. Hyde JE Pharmacol Ther; 1990; 48(1):45-59. PubMed ID: 2274577 [TBL] [Abstract][Full Text] [Related]
6. Antimalarial effect of cell penetrating peptides derived from the junctional region of Plasmodium falciparum dihydrofolate reductase-thymidylate synthase. Chaianantakul N; Sungkapong T; Supatip J; Kingsang P; Kamlaithong S; Suwanakitti N Peptides; 2020 Sep; 131():170372. PubMed ID: 32673701 [TBL] [Abstract][Full Text] [Related]
8. Evaluation of the activities of pyrimethamine analogs against Plasmodium vivax and Plasmodium falciparum dihydrofolate reductase-thymidylate synthase using in vitro enzyme inhibition and bacterial complementation assays. Bunyarataphan S; Leartsakulpanich U; Taweechai S; Tarnchompoo B; Kamchonwongpaisan S; Yuthavong Y Antimicrob Agents Chemother; 2006 Nov; 50(11):3631-7. PubMed ID: 16954316 [TBL] [Abstract][Full Text] [Related]
9. Regioisomerization of Antimalarial Drug WR99210 Explains the Inactivity of a Commercial Stock. Remcho TP; Guggilapu SD; Cruz P; Nardone GA; Heffernan G; O'Connor RD; Bewley CA; Wellems TE; Lane KD Antimicrob Agents Chemother; 2020 Dec; 65(1):. PubMed ID: 33077647 [TBL] [Abstract][Full Text] [Related]
10. A genetically hard-wired metabolic transcriptome in Plasmodium falciparum fails to mount protective responses to lethal antifolates. Ganesan K; Ponmee N; Jiang L; Fowble JW; White J; Kamchonwongpaisan S; Yuthavong Y; Wilairat P; Rathod PK PLoS Pathog; 2008 Nov; 4(11):e1000214. PubMed ID: 19023412 [TBL] [Abstract][Full Text] [Related]
11. Analysis in yeast of antimalaria drugs that target the dihydrofolate reductase of Plasmodium falciparum. Wooden JM; Hartwell LH; Vasquez B; Sibley CH Mol Biochem Parasitol; 1997 Mar; 85(1):25-40. PubMed ID: 9108546 [TBL] [Abstract][Full Text] [Related]
12. Genetic and metabolic analysis of folate salvage in the human malaria parasite Plasmodium falciparum. Wang P; Nirmalan N; Wang Q; Sims PF; Hyde JE Mol Biochem Parasitol; 2004 May; 135(1):77-87. PubMed ID: 15287589 [TBL] [Abstract][Full Text] [Related]
13. Transformation of Plasmodium falciparum malaria parasites by homologous integration of plasmids that confer resistance to pyrimethamine. Wu Y; Kirkman LA; Wellems TE Proc Natl Acad Sci U S A; 1996 Feb; 93(3):1130-4. PubMed ID: 8577727 [TBL] [Abstract][Full Text] [Related]
14. Translational up-regulation of antifolate drug targets in the human malaria parasite Plasmodium falciparum upon challenge with inhibitors. Nirmalan N; Sims PF; Hyde JE Mol Biochem Parasitol; 2004 Jul; 136(1):63-70. PubMed ID: 15138068 [TBL] [Abstract][Full Text] [Related]
15. Plasmodium falciparum: mutation pattern in the dihydrofolate reductase-thymidylate synthase genes of Vietnamese isolates, a novel mutation, and coexistence of two clones in a Thai patient. Zindrou S; Nguyen PD; Nguyen DS; Sköld O; Swedberg G Exp Parasitol; 1996 Oct; 84(1):56-64. PubMed ID: 8888732 [TBL] [Abstract][Full Text] [Related]
17. Exploiting structural analysis, in silico screening, and serendipity to identify novel inhibitors of drug-resistant falciparum malaria. Dasgupta T; Chitnumsub P; Kamchonwongpaisan S; Maneeruttanarungroj C; Nichols SE; Lyons TM; Tirado-Rives J; Jorgensen WL; Yuthavong Y; Anderson KS ACS Chem Biol; 2009 Jan; 4(1):29-40. PubMed ID: 19146480 [TBL] [Abstract][Full Text] [Related]
18. Similar trends of pyrimethamine resistance-associated mutations in Plasmodium vivax and P. falciparum. Alam MT; Bora H; Bharti PK; Saifi MA; Das MK; Dev V; Kumar A; Singh N; Dash AP; Das B; Wajihullah ; Sharma YD Antimicrob Agents Chemother; 2007 Mar; 51(3):857-63. PubMed ID: 17194833 [TBL] [Abstract][Full Text] [Related]
19. Rational drug design approach for overcoming drug resistance: application to pyrimethamine resistance in malaria. McKie JH; Douglas KT; Chan C; Roser SA; Yates R; Read M; Hyde JE; Dascombe MJ; Yuthavong Y; Sirawaraporn W J Med Chem; 1998 Apr; 41(9):1367-70. PubMed ID: 9554869 [TBL] [Abstract][Full Text] [Related]
20. Cloning and heterologous expression of Plasmodium ovale dihydrofolate reductase-thymidylate synthase gene. Tirakarn S; Riangrungroj P; Kongsaeree P; Imwong M; Yuthavong Y; Leartsakulpanich U Parasitol Int; 2012 Jun; 61(2):324-32. PubMed ID: 22234170 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]