BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 38239932)

  • 1. Probing Adenosine and P2 Receptors: Design of Novel Purines and Nonpurines as Selective Ligands.
    Jacobson KA
    Drug Dev Res; 2001; 52(1-2):178-186. PubMed ID: 38239932
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity relationships and molecular modeling of 3, 5-diacyl-2,4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists.
    Li AH; Moro S; Melman N; Ji XD; Jacobson KA
    J Med Chem; 1998 Aug; 41(17):3186-201. PubMed ID: 9703464
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acyl-Hydrazide Derivatives of a Xanthine Carboxylic Congener (XCC) as Selective Antagonists at Human A
    Kim YC; Karton Y; Ji XD; Melman N; Linden J; Jacobson KA
    Drug Dev Res; 1999 Aug; 47(4):178-188. PubMed ID: 35790094
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A
    Jacobson KA; Moro S; Kim YC; Li AH
    Drug Dev Res; 1998; 45(3-4):113-124. PubMed ID: 31808655
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pyran Template Approach to the Design of Novel A
    Li AH; Ji XD; Kim HS; Melman N; Jacobson KA
    Drug Dev Res; 1999 Dec; 48(4):171-177. PubMed ID: 27182099
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Engineering of A
    Jacobson KA; Kim HS; Ravi G; Kim SK; Lee K; Chen A; Chen W; Kim SG; Barak D; Liang BT; Gao ZG
    Drug Dev Res; 2003 Apr; 58(4):330-339. PubMed ID: 35799977
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.
    Gao ZG; Kim SK; Biadatti T; Chen W; Lee K; Barak D; Kim SG; Johnson CR; Jacobson KA
    J Med Chem; 2002 Sep; 45(20):4471-84. PubMed ID: 12238926
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Selective A(3) adenosine receptor antagonists derived from nucleosides containing a bicyclo[3.1.0]hexane ring system.
    Melman A; Wang B; Joshi BV; Gao ZG; Castro Sd; Heller CL; Kim SK; Jeong LS; Jacobson KA
    Bioorg Med Chem; 2008 Sep; 16(18):8546-56. PubMed ID: 18752961
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, biological activity, and molecular modeling of ribose-modified deoxyadenosine bisphosphate analogues as P2Y(1) receptor ligands.
    Nandanan E; Jang SY; Moro S; Kim HO; Siddiqui MA; Russ P; Marquez VE; Busson R; Herdewijn P; Harden TK; Boyer JL; Jacobson KA
    J Med Chem; 2000 Mar; 43(5):829-42. PubMed ID: 10715151
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Purine derivatives as ligands for A3 adenosine receptors.
    Joshi BV; Jacobson KA
    Curr Top Med Chem; 2005; 5(13):1275-95. PubMed ID: 16305531
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists.
    Hayallah AM; Sandoval-Ramírez J; Reith U; Schobert U; Preiss B; Schumacher B; Daly JW; Müller CE
    J Med Chem; 2002 Mar; 45(7):1500-10. PubMed ID: 11906291
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ribose modified nucleosides and nucleotides as ligands for purine receptors.
    Jacobson KA; Ravi RG; Nandanan E; Kim HS; Moro S; Kim YC; Lee K; Barak D; Marquez VE; Ji XD
    Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):333-41. PubMed ID: 11563046
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 6-phenyl-1,4-dihydropyridine derivatives as potent and selective A3 adenosine receptor antagonists.
    Jiang JL; van Rhee AM; Melman N; Ji XD; Jacobson KA
    J Med Chem; 1996 Nov; 39(23):4667-75. PubMed ID: 8917655
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2-Phenylimidazo[2,1-i]purin-5-ones: structure-activity relationships and characterization of potent and selective inverse agonists at Human A3 adenosine receptors.
    Ozola V; Thorand M; Diekmann M; Qurishi R; Schumacher B; Jacobson KA; Müller CE
    Bioorg Med Chem; 2003 Feb; 11(3):347-56. PubMed ID: 12517430
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interaction of 1,4-dihydropyridine and pyridine derivatives with adenosine receptors: selectivity for A3 receptors.
    van Rhee AM; Jiang JL; Melman N; Olah ME; Stiles GL; Jacobson KA
    J Med Chem; 1996 Jul; 39(15):2980-9. PubMed ID: 8709132
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists.
    Kim HS; Ohno M; Xu B; Kim HO; Choi Y; Ji XD; Maddileti S; Marquez VE; Harden TK; Jacobson KA
    J Med Chem; 2003 Nov; 46(23):4974-87. PubMed ID: 14584948
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of selective high affinity antagonists, agonists, and radioligands for the P2Y1 receptor.
    Houston D; Costanzi S; Jacobson KA; Harden TK
    Comb Chem High Throughput Screen; 2008 Jul; 11(6):410-9. PubMed ID: 18673269
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methanocarba analogues of purine nucleosides as potent and selective adenosine receptor agonists.
    Jacobson KA; Ji X; Li AH; Melman N; Siddiqui MA; Shin KJ; Marquez VE; Ravi RG
    J Med Chem; 2000 Jun; 43(11):2196-203. PubMed ID: 10841798
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rigidified A3 Adenosine Receptor Agonists: 1-Deazaadenine Modification Maintains High in Vivo Efficacy.
    Tosh DK; Crane S; Chen Z; Paoletta S; Gao ZG; Gizewski E; Auchampach JA; Salvemini D; Jacobson KA
    ACS Med Chem Lett; 2015 Jul; 6(7):804-8. PubMed ID: 26191370
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Probing Substituents in the 1- and 3-Position: Tetrahydropyrazino-Annelated Water-Soluble Xanthine Derivatives as Multi-Target Drugs With Potent Adenosine Receptor Antagonistic Activity.
    Koch P; Brunschweiger A; Namasivayam V; Ullrich S; Maruca A; Lazzaretto B; Küppers P; Hinz S; Hockemeyer J; Wiese M; Heer J; Alcaro S; Kiec-Kononowicz K; Müller CE
    Front Chem; 2018; 6():206. PubMed ID: 29998095
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.