BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 38241374)

  • 1. APOBEC3A induces DNA gaps through PRIMPOL and confers gap-associated therapeutic vulnerability.
    Kawale AS; Ran X; Patel PS; Saxena S; Lawrence MS; Zou L
    Sci Adv; 2024 Jan; 10(3):eadk2771. PubMed ID: 38241374
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Single-stranded DNA binding proteins influence APOBEC3A substrate preference.
    Brown AL; Collins CD; Thompson S; Coxon M; Mertz TM; Roberts SA
    Sci Rep; 2021 Oct; 11(1):21008. PubMed ID: 34697369
    [TBL] [Abstract][Full Text] [Related]  

  • 3. APOBEC3A damages the cellular genome during DNA replication.
    Green AM; Landry S; Budagyan K; Avgousti DC; Shalhout S; Bhagwat AS; Weitzman MD
    Cell Cycle; 2016; 15(7):998-1008. PubMed ID: 26918916
    [TBL] [Abstract][Full Text] [Related]  

  • 4. APOBEC3A and APOBEC3B Activities Render Cancer Cells Susceptible to ATR Inhibition.
    Buisson R; Lawrence MS; Benes CH; Zou L
    Cancer Res; 2017 Sep; 77(17):4567-4578. PubMed ID: 28698210
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cytosine Deaminase APOBEC3A Sensitizes Leukemia Cells to Inhibition of the DNA Replication Checkpoint.
    Green AM; Budagyan K; Hayer KE; Reed MA; Savani MR; Wertheim GB; Weitzman MD
    Cancer Res; 2017 Sep; 77(17):4579-4588. PubMed ID: 28655787
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms.
    Leung W; Simoneau A; Saxena S; Jackson J; Patel PS; Limbu M; Vindigni A; Zou L
    Cell Rep; 2023 Jul; 42(7):112792. PubMed ID: 37454295
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Loss of the abasic site sensor HMCES is synthetic lethal with the activity of the APOBEC3A cytosine deaminase in cancer cells.
    Biayna J; Garcia-Cao I; Álvarez MM; Salvadores M; Espinosa-Carrasco J; McCullough M; Supek F; Stracker TH
    PLoS Biol; 2021 Mar; 19(3):e3001176. PubMed ID: 33788831
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Visualization of uracils created by APOBEC3A using UdgX shows colocalization with RPA at stalled replication forks.
    Stewart JA; Schauer G; Bhagwat AS
    Nucleic Acids Res; 2020 Nov; 48(20):e118. PubMed ID: 33074285
    [TBL] [Abstract][Full Text] [Related]  

  • 9. APOBEC3A Loop 1 Is a Determinant for Single-Stranded DNA Binding and Deamination.
    Ziegler SJ; Hu Y; Devarkar SC; Xiong Y
    Biochemistry; 2019 Sep; 58(37):3838-3847. PubMed ID: 31448897
    [TBL] [Abstract][Full Text] [Related]  

  • 10. HMCES Maintains Replication Fork Progression and Prevents Double-Strand Breaks in Response to APOBEC Deamination and Abasic Site Formation.
    Mehta KPM; Lovejoy CA; Zhao R; Heintzman DR; Cortez D
    Cell Rep; 2020 Jun; 31(9):107705. PubMed ID: 32492421
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HPV11 E6 mutation by overexpression of APOBEC3A and effects of interferon-ω on APOBEC3s and HPV11 E6 expression in HPV11.HaCaT cells.
    Wang Y; Li X; Song S; Sun Y; Zhang J; Yu C; Chen W
    Virol J; 2017 Nov; 14(1):211. PubMed ID: 29100527
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Single-Molecule Force Spectroscopy Studies of APOBEC3A-Single-Stranded DNA Complexes.
    Shlyakhtenko LS; Dutta S; Li M; Harris RS; Lyubchenko YL
    Biochemistry; 2016 Jun; 55(22):3102-6. PubMed ID: 27182892
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The DNA damage induced by the Cytosine Deaminase APOBEC3A Leads to the production of ROS.
    Niocel M; Appourchaux R; Nguyen XN; Delpeuch M; Cimarelli A
    Sci Rep; 2019 Mar; 9(1):4714. PubMed ID: 30886206
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PRIMPOL-Mediated Adaptive Response Suppresses Replication Fork Reversal in BRCA-Deficient Cells.
    Quinet A; Tirman S; Jackson J; Šviković S; Lemaçon D; Carvajal-Maldonado D; González-Acosta D; Vessoni AT; Cybulla E; Wood M; Tavis S; Batista LFZ; Méndez J; Sale JE; Vindigni A
    Mol Cell; 2020 Feb; 77(3):461-474.e9. PubMed ID: 31676232
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural determinants of human APOBEC3A enzymatic and nucleic acid binding properties.
    Mitra M; Hercík K; Byeon IJ; Ahn J; Hill S; Hinchee-Rodriguez K; Singer D; Byeon CH; Charlton LM; Nam G; Heidecker G; Gronenborn AM; Levin JG
    Nucleic Acids Res; 2014 Jan; 42(2):1095-110. PubMed ID: 24163103
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Substrate sequence selectivity of APOBEC3A implicates intra-DNA interactions.
    Silvas TV; Hou S; Myint W; Nalivaika E; Somasundaran M; Kelch BA; Matsuo H; Kurt Yilmaz N; Schiffer CA
    Sci Rep; 2018 May; 8(1):7511. PubMed ID: 29760455
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Unraveling the Enzyme-Substrate Properties for APOBEC3A-Mediated RNA Editing.
    Kim K; Shi AB; Kelley K; Chen XS
    J Mol Biol; 2023 Sep; 435(17):168198. PubMed ID: 37442413
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Temporally distinct post-replicative repair mechanisms fill PRIMPOL-dependent ssDNA gaps in human cells.
    Tirman S; Quinet A; Wood M; Meroni A; Cybulla E; Jackson J; Pegoraro S; Simoneau A; Zou L; Vindigni A
    Mol Cell; 2021 Oct; 81(19):4026-4040.e8. PubMed ID: 34624216
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Human Papillomavirus 16 E7 Stabilizes APOBEC3A Protein by Inhibiting Cullin 2-Dependent Protein Degradation.
    Westrich JA; Warren CJ; Klausner MJ; Guo K; Liu CW; Santiago ML; Pyeon D
    J Virol; 2018 Apr; 92(7):. PubMed ID: 29367246
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction with the CCT chaperonin complex limits APOBEC3A cytidine deaminase cytotoxicity.
    Green AM; DeWeerd RA; O'Leary DR; Hansen AR; Hayer KE; Kulej K; Dineen AS; Szeto JH; Garcia BA; Weitzman MD
    EMBO Rep; 2021 Sep; 22(9):e52145. PubMed ID: 34347354
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.