BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 38241700)

  • 21. Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition.
    Rajendran P; Johnson G; Li L; Chen YS; Dashwood M; Nguyen N; Ulusan A; Ertem F; Zhang M; Li J; Sun D; Huang Y; Wang S; Leung HC; Lieberman D; Beaver L; Ho E; Bedford M; Chang K; Vilar E; Dashwood R
    Cancer Res; 2019 Mar; 79(5):918-927. PubMed ID: 30643017
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A novel dual epigenetic approach targeting BET proteins and HDACs in Group 3 (MYC-driven) Medulloblastoma.
    Kling MJ; Kesherwani V; Mishra NK; Alexander G; McIntyre EM; Ray S; Challagundla KB; Joshi SS; Coulter DW; Chaturvedi NK
    J Exp Clin Cancer Res; 2022 Nov; 41(1):321. PubMed ID: 36357906
    [TBL] [Abstract][Full Text] [Related]  

  • 23. RNAs interact with BRD4 to promote enhanced chromatin engagement and transcription activation.
    Rahnamoun H; Lee J; Sun Z; Lu H; Ramsey KM; Komives EA; Lauberth SM
    Nat Struct Mol Biol; 2018 Aug; 25(8):687-697. PubMed ID: 30076409
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The YEATS domain epigenetic reader proteins ENL and AF9 and their therapeutic value in leukemia.
    Hu H; Muntean AG
    Exp Hematol; 2023 Aug; 124():15-21. PubMed ID: 37295550
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The Intrinsically Disordered Proteins MLLT3 (AF9) and MLLT1 (ENL) - Multimodal Transcriptional Switches With Roles in Normal Hematopoiesis, MLL Fusion Leukemia, and Kidney Cancer.
    Kabra A; Bushweller J
    J Mol Biol; 2022 Jan; 434(1):167117. PubMed ID: 34174329
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Epigenetic blockade of neoplastic transformation by bromodomain and extra-terminal (BET) domain protein inhibitor JQ-1.
    Zhang C; Su ZY; Wang L; Shu L; Yang Y; Guo Y; Pung D; Bountra C; Kong AN
    Biochem Pharmacol; 2016 Oct; 117():35-45. PubMed ID: 27520485
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Targeting the epigenetic reader "BET" as a therapeutic strategy for cancer.
    Wahi A; Manchanda N; Jain P; Jadhav HR
    Bioorg Chem; 2023 Nov; 140():106833. PubMed ID: 37683545
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The BET inhibitor GNE-987 effectively induces anti-cancer effects in T-cell acute lymphoblastic leukemia by targeting enhancer regulated genes.
    Yu J; Yang Y; Zhou R; Tao Y; Zhu F; Jiao W; Zhang Z; Ji T; Li T; Fang F; Xie Y; Wu D; Zhuo R; Li X; Chen Y; Yin H; Wang J; Pan J
    Carcinogenesis; 2024 Jun; 45(6):424-435. PubMed ID: 38302114
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9.
    Christott T; Bennett J; Coxon C; Monteiro O; Giroud C; Beke V; Felce SL; Gamble V; Gileadi C; Poda G; Al-Awar R; Farnie G; Fedorov O
    SLAS Discov; 2019 Feb; 24(2):133-141. PubMed ID: 30359161
    [TBL] [Abstract][Full Text] [Related]  

  • 30. BET Bromodomain as a Target of Epigenetic Therapy.
    Noguchi-Yachide T
    Chem Pharm Bull (Tokyo); 2016; 64(6):540-7. PubMed ID: 27250788
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Conformational and Thermodynamic Differences Underlying Wild-Type and Mutant Eleven-Nineteen-Leukemia YEATS Domain Specificity for Epigenetic Marks.
    Baweja L; Wereszczynski J
    J Chem Inf Model; 2023 Feb; 63(4):1229-1238. PubMed ID: 36786550
    [TBL] [Abstract][Full Text] [Related]  

  • 32. EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes.
    Huang Y; Durall RT; Luong NM; Hertzler HJ; Huang J; Gokhale PC; Leeper BA; Persky NS; Root DE; Anekal PV; Montero Llopis PDLM; David CN; Kutok JL; Raimondi A; Saluja K; Luo J; Zahnow CA; Adane B; Stegmaier K; Hawkins CE; Ponne C; Le Q; Shapiro GI; Lemieux ME; Eagen KP; French CA
    Cancer Res; 2023 Dec; 83(23):3956-3973. PubMed ID: 37747726
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The epigenetic reader Brd4 is required for osteoblast differentiation.
    Paradise CR; Galvan ML; Kubrova E; Bowden S; Liu E; Carstens MF; Thaler R; Stein GS; van Wijnen AJ; Dudakovic A
    J Cell Physiol; 2020 Jun; 235(6):5293-5304. PubMed ID: 31868237
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Defining super-enhancers by highly ranked histone H4 multi-acetylation levels identifies transcription factors associated with glioblastoma stem-like properties.
    Das ND; Chang JC; Hon CC; Kelly ST; Ito S; Lizio M; Kaczkowski B; Watanabe H; Katsushima K; Natsume A; Koseki H; Kondo Y; Minoda A; Umehara T
    BMC Genomics; 2023 Sep; 24(1):574. PubMed ID: 37759202
    [TBL] [Abstract][Full Text] [Related]  

  • 35. EWS/ETS-Driven Ewing Sarcoma Requires BET Bromodomain Proteins.
    Gollavilli PN; Pawar A; Wilder-Romans K; Natesan R; Engelke CG; Dommeti VL; Krishnamurthy PM; Nallasivam A; Apel IJ; Xu T; Qin ZS; Feng FY; Asangani IA
    Cancer Res; 2018 Aug; 78(16):4760-4773. PubMed ID: 29898995
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Enhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader Proteins.
    Sartor GC; Malvezzi AM; Kumar A; Andrade NS; Wiedner HJ; Vilca SJ; Janczura KJ; Bagheri A; Al-Ali H; Powell SK; Brown PT; Volmar CH; Foster TC; Zeier Z; Wahlestedt C
    J Neurosci; 2019 Jan; 39(4):612-626. PubMed ID: 30504275
    [TBL] [Abstract][Full Text] [Related]  

  • 37. KLF7 regulates super-enhancer-driven IGF2BP2 overexpression to promote the progression of head and neck squamous cell carcinoma.
    Cai H; Liang J; Jiang Y; Wang Z; Li H; Wang W; Wang C; Hou J
    J Exp Clin Cancer Res; 2024 Mar; 43(1):69. PubMed ID: 38443991
    [TBL] [Abstract][Full Text] [Related]  

  • 38. BRD4 Promotes Gastric Cancer Progression and Metastasis through Acetylation-Dependent Stabilization of Snail.
    Qin ZY; Wang T; Su S; Shen LT; Zhu GX; Liu Q; Zhang L; Liu KW; Zhang Y; Zhou ZH; Zhang XN; Wen LZ; Yao YL; Sun WJ; Guo Y; Liu KJ; Liu L; Wang XW; Wei YL; Wang J; Xiao HL; Liu P; Bian XW; Chen DF; Wang B
    Cancer Res; 2019 Oct; 79(19):4869-4881. PubMed ID: 31311807
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer.
    Zuber V; Bettella F; Witoelar A; ; ; ; ; Andreassen OA; Mills IG; Urbanucci A
    BMC Genomics; 2017 Mar; 18(1):270. PubMed ID: 28359301
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Histone cross-talk connects protein phosphatase 1α (PP1α) and histone deacetylase (HDAC) pathways to regulate the functional transition of bromodomain-containing 4 (BRD4) for inducible gene expression.
    Hu X; Lu X; Liu R; Ai N; Cao Z; Li Y; Liu J; Yu B; Liu K; Wang H; Zhou C; Wang Y; Han A; Ding F; Chen R
    J Biol Chem; 2014 Aug; 289(33):23154-23167. PubMed ID: 24939842
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.