167 related articles for article (PubMed ID: 38242131)
1. Mutations in FUS lead to synaptic dysregulation in ALS-iPSC derived neurons.
Shum C; Hedges EC; Allison J; Lee YB; Arias N; Cocks G; Chandran S; Ruepp MD; Shaw CE; Nishimura AL
Stem Cell Reports; 2024 Feb; 19(2):187-195. PubMed ID: 38242131
[TBL] [Abstract][Full Text] [Related]
2. Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways.
Blokhuis AM; Koppers M; Groen EJN; van den Heuvel DMA; Dini Modigliani S; Anink JJ; Fumoto K; van Diggelen F; Snelting A; Sodaar P; Verheijen BM; Demmers JAA; Veldink JH; Aronica E; Bozzoni I; den Hertog J; van den Berg LH; Pasterkamp RJ
Acta Neuropathol; 2016 Aug; 132(2):175-196. PubMed ID: 27164932
[TBL] [Abstract][Full Text] [Related]
3. Altered calcium dynamics and glutamate receptor properties in iPSC-derived motor neurons from ALS patients with C9orf72, FUS, SOD1 or TDP43 mutations.
Bursch F; Kalmbach N; Naujock M; Staege S; Eggenschwiler R; Abo-Rady M; Japtok J; Guo W; Hensel N; Reinhardt P; Boeckers TM; Cantz T; Sterneckert J; Van Den Bosch L; Hermann A; Petri S; Wegner F
Hum Mol Genet; 2019 Sep; 28(17):2835-2850. PubMed ID: 31108504
[TBL] [Abstract][Full Text] [Related]
4. Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging.
Japtok J; Lojewski X; Naumann M; Klingenstein M; Reinhardt P; Sterneckert J; Putz S; Demestre M; Boeckers TM; Ludolph AC; Liebau S; Storch A; Hermann A
Neurobiol Dis; 2015 Oct; 82():420-429. PubMed ID: 26253605
[TBL] [Abstract][Full Text] [Related]
5. FUS ALS neurons activate major stress pathways and reduce translation as an early protective mechanism against neurodegeneration.
Szewczyk B; Günther R; Japtok J; Frech MJ; Naumann M; Lee HO; Hermann A
Cell Rep; 2023 Feb; 42(2):112025. PubMed ID: 36696267
[TBL] [Abstract][Full Text] [Related]
6. HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients.
Guo W; Naujock M; Fumagalli L; Vandoorne T; Baatsen P; Boon R; Ordovás L; Patel A; Welters M; Vanwelden T; Geens N; Tricot T; Benoy V; Steyaert J; Lefebvre-Omar C; Boesmans W; Jarpe M; Sterneckert J; Wegner F; Petri S; Bohl D; Vanden Berghe P; Robberecht W; Van Damme P; Verfaillie C; Van Den Bosch L
Nat Commun; 2017 Oct; 8(1):861. PubMed ID: 29021520
[TBL] [Abstract][Full Text] [Related]
7. The fused in sarcoma protein forms cytoplasmic aggregates in motor neurons derived from integration-free induced pluripotent stem cells generated from a patient with familial amyotrophic lateral sclerosis carrying the FUS-P525L mutation.
Liu X; Chen J; Liu W; Li X; Chen Q; Liu T; Gao S; Deng M
Neurogenetics; 2015 Jul; 16(3):223-31. PubMed ID: 25912081
[TBL] [Abstract][Full Text] [Related]
8. Aberrant axon branching via Fos-B dysregulation in FUS-ALS motor neurons.
Akiyama T; Suzuki N; Ishikawa M; Fujimori K; Sone T; Kawada J; Funayama R; Fujishima F; Mitsuzawa S; Ikeda K; Ono H; Shijo T; Osana S; Shirota M; Nakagawa T; Kitajima Y; Nishiyama A; Izumi R; Morimoto S; Okada Y; Kamei T; Nishida M; Nogami M; Kaneda S; Ikeuchi Y; Mitsuhashi H; Nakayama K; Fujii T; Warita H; Okano H; Aoki M
EBioMedicine; 2019 Jul; 45():362-378. PubMed ID: 31262712
[TBL] [Abstract][Full Text] [Related]
9. FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation.
Birsa N; Ule AM; Garone MG; Tsang B; Mattedi F; Chong PA; Humphrey J; Jarvis S; Pisiren M; Wilkins OG; Nosella ML; Devoy A; Bodo C; de la Fuente RF; Fisher EMC; Rosa A; Viero G; Forman-Kay JD; Schiavo G; Fratta P
Sci Adv; 2021 Jul; 7(30):. PubMed ID: 34290090
[TBL] [Abstract][Full Text] [Related]
10. Generation of two induced pluripotent stem cell lines with heterozygous and homozygous amyotrophic lateral sclerosis-causing mutation P525L (c.1574C > T) in FUS gene.
Akter M; Cui H; Abir Hosain M; Ding B
Stem Cell Res; 2023 Jun; 69():103103. PubMed ID: 37116345
[TBL] [Abstract][Full Text] [Related]
11. Establishment of In Vitro FUS-Associated Familial Amyotrophic Lateral Sclerosis Model Using Human Induced Pluripotent Stem Cells.
Ichiyanagi N; Fujimori K; Yano M; Ishihara-Fujisaki C; Sone T; Akiyama T; Okada Y; Akamatsu W; Matsumoto T; Ishikawa M; Nishimoto Y; Ishihara Y; Sakuma T; Yamamoto T; Tsuiji H; Suzuki N; Warita H; Aoki M; Okano H
Stem Cell Reports; 2016 Apr; 6(4):496-510. PubMed ID: 26997647
[TBL] [Abstract][Full Text] [Related]
12. Directly converted patient-specific induced neurons mirror the neuropathology of FUS with disrupted nuclear localization in amyotrophic lateral sclerosis.
Lim SM; Choi WJ; Oh KW; Xue Y; Choi JY; Kim SH; Nahm M; Kim YE; Lee J; Noh MY; Lee S; Hwang S; Ki CS; Fu XD; Kim SH
Mol Neurodegener; 2016 Jan; 11():8. PubMed ID: 26795035
[TBL] [Abstract][Full Text] [Related]
13. Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.
Zhu Y; Burg T; Neyrinck K; Vervliet T; Nami F; Vervoort E; Ahuja K; Sassano ML; Chai YC; Tharkeshwar AK; De Smedt J; Hu H; Bultynck G; Agostinis P; Swinnen JV; Van Den Bosch L; da Costa RFM; Verfaillie C
Acta Neuropathol; 2024 Jan; 147(1):6. PubMed ID: 38170217
[TBL] [Abstract][Full Text] [Related]
14. A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons.
Capauto D; Colantoni A; Lu L; Santini T; Peruzzi G; Biscarini S; Morlando M; Shneider NA; Caffarelli E; Laneve P; Bozzoni I
Mol Neurobiol; 2018 Oct; 55(10):7635-7651. PubMed ID: 29430619
[TBL] [Abstract][Full Text] [Related]
15. ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
Kamelgarn M; Chen J; Kuang L; Jin H; Kasarskis EJ; Zhu H
Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E11904-E11913. PubMed ID: 30455313
[TBL] [Abstract][Full Text] [Related]
16. Generation of a human induced pluripotent stem cell line (SMUSHi002-A) from an ALS patient carrying a heterozygous mutation c.1562G > A in the FUS gene.
Tang M; Xiong M; Zhou W; Lei J; Huang M; Huang C; Wang F; Liu J; Li J; Xu X
Stem Cell Res; 2024 Feb; 74():103286. PubMed ID: 38141357
[TBL] [Abstract][Full Text] [Related]
17. Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition.
Pelaez MC; Desmeules A; Gelon PA; Glasson B; Marcadet L; Rodgers A; Phaneuf D; Pozzi S; Dutchak PA; Julien JP; Sephton CF
Acta Neuropathol Commun; 2023 Nov; 11(1):182. PubMed ID: 37974279
[TBL] [Abstract][Full Text] [Related]
18. Generation of six induced pluripotent stem cell lines from patients with amyotrophic lateral sclerosis with associated genetic mutations in either FUS or ANXA11.
Hedges EC; Topp S; Shaw CE; Nishimura AL
Stem Cell Res; 2021 Apr; 52():102246. PubMed ID: 33610019
[TBL] [Abstract][Full Text] [Related]
19. lncRNA Sequencing Reveals Neurodegeneration-Associated FUS Mutations Alter Transcriptional Landscape of iPS Cells That Persists in Motor Neurons.
Provasek VE; Kodavati M; Guo W; Wang H; Boldogh I; Van Den Bosch L; Britz G; Hegde ML
Cells; 2023 Oct; 12(20):. PubMed ID: 37887305
[TBL] [Abstract][Full Text] [Related]
20. Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis.
Tyzack GE; Luisier R; Taha DM; Neeves J; Modic M; Mitchell JS; Meyer I; Greensmith L; Newcombe J; Ule J; Luscombe NM; Patani R
Brain; 2019 Sep; 142(9):2572-2580. PubMed ID: 31368485
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]