BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 38254638)

  • 1. GDF-15 Inhibits ADP-Induced Human Platelet Aggregation through the GFRAL/RET Signaling Complex.
    Xie B; Tang W; Wen S; Chen F; Yang C; Wang M; Yang Y; Liang W
    Biomolecules; 2023 Dec; 14(1):. PubMed ID: 38254638
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Upregulated GDF-15 expression facilitates pancreatic ductal adenocarcinoma progression through orphan receptor GFRAL.
    Zhao Z; Zhang J; Yin L; Yang J; Zheng Y; Zhang M; Ni B; Wang H
    Aging (Albany NY); 2020 Nov; 12(22):22564-22581. PubMed ID: 33201838
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway.
    Pelicci G; Troglio F; Bodini A; Melillo RM; Pettirossi V; Coda L; De Giuseppe A; Santoro M; Pelicci PG
    Mol Cell Biol; 2002 Oct; 22(20):7351-63. PubMed ID: 12242309
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GDF-15 inhibits integrin activation and mouse neutrophil recruitment through the ALK-5/TGF-βRII heterodimer.
    Artz A; Butz S; Vestweber D
    Blood; 2016 Jul; 128(4):529-41. PubMed ID: 27235139
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thrombopoietin complements G(i)- but not G(q)-dependent pathways for integrin {alpha}(IIb){beta}(3) activation and platelet aggregation.
    Campus F; Lova P; Bertoni A; Sinigaglia F; Balduini C; Torti M
    J Biol Chem; 2005 Jul; 280(26):24386-95. PubMed ID: 15863506
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor.
    Hayashi H; Ichihara M; Iwashita T; Murakami H; Shimono Y; Kawai K; Kurokawa K; Murakumo Y; Imai T; Funahashi H; Nakao A; Takahashi M
    Oncogene; 2000 Sep; 19(39):4469-75. PubMed ID: 11002419
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Growth differentiation factor-15 prevents low potassium-induced cell death of cerebellar granule neurons by differential regulation of Akt and ERK pathways.
    Subramaniam S; Strelau J; Unsicker K
    J Biol Chem; 2003 Mar; 278(11):8904-12. PubMed ID: 12514175
    [TBL] [Abstract][Full Text] [Related]  

  • 8. GM1 ganglioside enhances Ret signaling in striatum.
    Newburn EN; Duchemin AM; Neff NH; Hadjiconstantinou M
    J Neurochem; 2014 Aug; 130(4):541-54. PubMed ID: 24821093
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice.
    Suriben R; Chen M; Higbee J; Oeffinger J; Ventura R; Li B; Mondal K; Gao Z; Ayupova D; Taskar P; Li D; Starck SR; Chen HH; McEntee M; Katewa SD; Phung V; Wang M; Kekatpure A; Lakshminarasimhan D; White A; Olland A; Haldankar R; Solloway MJ; Hsu JY; Wang Y; Tang J; Lindhout DA; Allan BB
    Nat Med; 2020 Aug; 26(8):1264-1270. PubMed ID: 32661391
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase.
    Besset V; Scott RP; Ibáñez CF
    J Biol Chem; 2000 Dec; 275(50):39159-66. PubMed ID: 10995764
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors.
    Jin J; Quinton TM; Zhang J; Rittenhouse SE; Kunapuli SP
    Blood; 2002 Jan; 99(1):193-8. PubMed ID: 11756171
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of phosphoinositide 3-kinase beta in platelet aggregation and thromboxane A2 generation mediated by Gi signalling pathways.
    Garcia A; Kim S; Bhavaraju K; Schoenwaelder SM; Kunapuli SP
    Biochem J; 2010 Jul; 429(2):369-77. PubMed ID: 20441566
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insights Into Mechanisms of GDF15 and Receptor GFRAL: Therapeutic Targets.
    Rochette L; Zeller M; Cottin Y; Vergely C
    Trends Endocrinol Metab; 2020 Dec; 31(12):939-951. PubMed ID: 33172749
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting Obesity and Cachexia: Identification of the GFRAL Receptor-MIC-1/GDF15 Pathway.
    Breit SN; Tsai VW; Brown DA
    Trends Mol Med; 2017 Dec; 23(12):1065-1067. PubMed ID: 29129392
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Growth differentiation factor 15 (GDF-15) in endocrinology.
    Iglesias P; Silvestre RA; Díez JJ
    Endocrine; 2023 Sep; 81(3):419-431. PubMed ID: 37129758
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Platelets possess functional TGF-beta receptors and Smad2 protein.
    Lev PR; Salim JP; Marta RF; Osorio MJ; Goette NP; Molinas FC
    Platelets; 2007 Feb; 18(1):35-42. PubMed ID: 17365852
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Submission for Special Issue: The Role of Platelet Activation in the Pathophysiology of HIV, Tuberculosis, and Pneumococcal Disease. Bedaquiline Suppresses ADP-Mediated Activation of Human Platelets
    Tintinger GR; Theron AJ; Steel HC; Cholo MC; Nel JG; Feldman C; Anderson R
    Front Immunol; 2020; 11():621148. PubMed ID: 33717055
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells.
    Trupp M; Scott R; Whittemore SR; Ibáñez CF
    J Biol Chem; 1999 Jul; 274(30):20885-94. PubMed ID: 10409632
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GDF-15 enhances intracellular Ca2+ by increasing Cav1.3 expression in rat cerebellar granule neurons.
    Lu JM; Wang CY; Hu C; Fang YJ; Mei YA
    Biochem J; 2016 Jul; 473(13):1895-904. PubMed ID: 27114559
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Small-Molecule Ligands that Bind the RET Receptor Activate Neuroprotective Signals Independent of but Modulated by Coreceptor GFR
    Jmaeff S; Sidorova Y; Lippiatt H; Barcelona PF; Nedev H; Saragovi LM; Hancock MA; Saarma M; Saragovi HU
    Mol Pharmacol; 2020 Jul; 98(1):1-12. PubMed ID: 32362584
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.