BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 38270591)

  • 1. Forward Genetic Screens Identify Mechanisms of Resistance to Small-Molecule Lactate Dehydrogenase Inhibitors.
    Frank AR; Vandiver F; McFadden DG
    ACS Chem Biol; 2024 Feb; 19(2):471-482. PubMed ID: 38270591
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Forward genetic screens identify mechanisms of resistance to small molecule lactate dehydrogenase inhibitors.
    Frank AR; Vandiver F; McFadden DG
    bioRxiv; 2023 Sep; ():. PubMed ID: 37808702
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mitochondrial-Encoded Complex I Impairment Induces a Targetable Dependency on Aerobic Fermentation in Hürthle Cell Carcinoma of the Thyroid.
    Frank AR; Li V; Shelton SD; Kim J; Stott GM; Neckers LM; Xie Y; Williams NS; Mishra P; McFadden DG
    Cancer Discov; 2023 Aug; 13(8):1884-1903. PubMed ID: 37262072
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors.
    Máximo V; Soares P; Lima J; Cameselle-Teijeiro J; Sobrinho-Simões M
    Am J Pathol; 2002 May; 160(5):1857-65. PubMed ID: 12000737
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enhancement of mitochondrial biogenesis and paradoxical inhibition of lactate dehydrogenase mediated by 14-3-3η in oncocytomas.
    Feng J; Zhang Q; Li C; Zhou Y; Zhao S; Hong L; Song Q; Yu S; Hu C; Wang H; Mao C; Shepard MJ; Hao S; Dominah G; Sun M; Wan H; Park DM; Gilbert MR; Xu G; Zhuang Z; Zhang Y
    J Pathol; 2018 Jul; 245(3):361-372. PubMed ID: 29704241
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hürthle cell tumours of the thyroid. A review with emphasis on mitochondrial abnormalities with clinical relevance.
    Máximo V; Sobrinho-Simões M
    Virchows Arch; 2000 Aug; 437(2):107-15. PubMed ID: 10993269
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Defective mitochondrial ATP synthesis in oxyphilic thyroid tumors.
    Savagner F; Franc B; Guyetant S; Rodien P; Reynier P; Malthiery Y
    J Clin Endocrinol Metab; 2001 Oct; 86(10):4920-5. PubMed ID: 11600563
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The biology and the genetics of Hurthle cell tumors of the thyroid.
    Máximo V; Lima J; Prazeres H; Soares P; Sobrinho-Simões M
    Endocr Relat Cancer; 2012 Aug; 19(4):R131-47. PubMed ID: 22514109
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Defective oxidative phosphorylation in thyroid oncocytic carcinoma is associated with pathogenic mitochondrial DNA mutations affecting complexes I and III.
    Bonora E; Porcelli AM; Gasparre G; Biondi A; Ghelli A; Carelli V; Baracca A; Tallini G; Martinuzzi A; Lenaz G; Rugolo M; Romeo G
    Cancer Res; 2006 Jun; 66(12):6087-96. PubMed ID: 16778181
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Molecular Landscape of Hürthle Cell Thyroid Cancer Is Associated with Altered Mitochondrial Function-A Comprehensive Review.
    Kumari S; Adewale R; Klubo-Gwiezdzinska J
    Cells; 2020 Jun; 9(7):. PubMed ID: 32605113
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Papillary thyroid carcinoma tall cell variant shares accumulation of mitochondria, mitochondrial DNA mutations, and loss of oxidative phosphorylation complex I integrity with oncocytic tumors.
    Tsybrovskyy O; De Luise M; de Biase D; Caporali L; Fiorini C; Gasparre G; Carelli V; Hackl D; Imamovic L; Haim S; Sobrinho-Simões M; Tallini G
    J Pathol Clin Res; 2022 Mar; 8(2):155-168. PubMed ID: 34792302
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma.
    Gopal RK; Kübler K; Calvo SE; Polak P; Livitz D; Rosebrock D; Sadow PM; Campbell B; Donovan SE; Amin S; Gigliotti BJ; Grabarek Z; Hess JM; Stewart C; Braunstein LZ; Arndt PF; Mordecai S; Shih AR; Chaves F; Zhan T; Lubitz CC; Kim J; Iafrate AJ; Wirth L; Parangi S; Leshchiner I; Daniels GH; Mootha VK; Dias-Santagata D; Getz G; McFadden DG
    Cancer Cell; 2018 Aug; 34(2):242-255.e5. PubMed ID: 30107175
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio.
    Ross JM; Öberg J; Brené S; Coppotelli G; Terzioglu M; Pernold K; Goiny M; Sitnikov R; Kehr J; Trifunovic A; Larsson NG; Hoffer BJ; Olson L
    Proc Natl Acad Sci U S A; 2010 Nov; 107(46):20087-92. PubMed ID: 21041631
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Short Review: Genomic Alterations in Hürthle Cell Carcinoma.
    Ganly I; McFadden DG
    Thyroid; 2019 Apr; 29(4):471-479. PubMed ID: 30848171
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Somatic and germline mutation in GRIM-19, a dual function gene involved in mitochondrial metabolism and cell death, is linked to mitochondrion-rich (Hurthle cell) tumours of the thyroid.
    Máximo V; Botelho T; Capela J; Soares P; Lima J; Taveira A; Amaro T; Barbosa AP; Preto A; Harach HR; Williams D; Sobrinho-Simões M
    Br J Cancer; 2005 May; 92(10):1892-8. PubMed ID: 15841082
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hürthle (oncocytic) cell tumors of thyroid: etiopathogenesis, diagnosis and clinical significance.
    Sobrinho-Simões M; Máximo V; Castro IV; Fonseca E; Soares P; Garcia-Rostan G; Oliveira MC
    Int J Surg Pathol; 2005 Jan; 13(1):29-35. PubMed ID: 15735852
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mitochondrial activities of a cell line derived from thyroid Hürthle cell tumors.
    Stankov K; Biondi A; D'Aurelio M; Gasparre G; Falasca A; Romeo G; Lenaz G
    Thyroid; 2006 Apr; 16(4):325-31. PubMed ID: 16646677
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Clinical utility of EZH1 mutations in the diagnosis of follicular-patterned thyroid tumors.
    Jung CK; Kim Y; Jeon S; Jo K; Lee S; Bae JS
    Hum Pathol; 2018 Nov; 81():9-17. PubMed ID: 29723601
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Oncocytic tumors are marked by enhanced mitochondrial content and mtDNA mutations of complex I in Chinese patients.
    Lyu L; Wang Q; Song S; Li L; Zhou H; Li M; Jiang Z; Zhou C; Chen G; Lyu J; Bai Y
    Mitochondrion; 2019 Mar; 45():1-6. PubMed ID: 29386142
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial activity in XTC.UC1 cells derived from thyroid oncocytoma.
    Savagner F; Chevrollier A; Loiseau D; Morgan C; Reynier P; Clark O; Stepien G; Malthiery Y
    Thyroid; 2001 Apr; 11(4):327-33. PubMed ID: 11349830
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.