132 related articles for article (PubMed ID: 38280358)
1. Proapoptotic effect of WS-299 induced by NOXA accumulation and NRF2-counterbalanced oxidative stress damage through targeting RBX1-UBE2M interaction in gastric cancers.
Ma T; Song Q; Cheng B; Guo E; Wang X; Li M; Dai M; Li S; Feng S; Yu B
Bioorg Chem; 2024 Mar; 144():107142. PubMed ID: 38280358
[TBL] [Abstract][Full Text] [Related]
2. UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F.
Zhou W; Xu J; Tan M; Li H; Li H; Wei W; Sun Y
Mol Cell; 2018 Jun; 70(6):1008-1024.e6. PubMed ID: 29932898
[TBL] [Abstract][Full Text] [Related]
3. The Ube2m-Rbx1 neddylation-Cullin-RING-Ligase proteins are essential for the maintenance of Regulatory T cell fitness.
Wu D; Li H; Liu M; Qin J; Sun Y
Nat Commun; 2022 May; 13(1):3021. PubMed ID: 35641500
[TBL] [Abstract][Full Text] [Related]
4. Neddylation-CRLs regulate the functions of Treg immune cells.
Wu D; Sun Y
Bioessays; 2023 Apr; 45(4):e2200222. PubMed ID: 36709423
[TBL] [Abstract][Full Text] [Related]
5. Cullin-5 neddylation-mediated NOXA degradation is enhanced by PRDX1 oligomers in colorectal cancer.
Xu S; Ma Y; Tong Q; Yang J; Liu J; Wang Y; Li G; Zeng J; Fang S; Li F; Xie X; Zhang J
Cell Death Dis; 2021 Mar; 12(3):265. PubMed ID: 33712558
[TBL] [Abstract][Full Text] [Related]
6. Gossypol inhibits cullin neddylation by targeting SAG-CUL5 and RBX1-CUL1 complexes.
Yu Q; Hu Z; Shen Y; Jiang Y; Pan P; Hou T; Pan ZQ; Huang J; Sun Y
Neoplasia; 2020 Apr; 22(4):179-191. PubMed ID: 32145688
[TBL] [Abstract][Full Text] [Related]
7. Micafungin: A promising inhibitor of UBE2M in cancer cell growth suppression.
Mamun MAA; Liu S; Zhao L; Zhao L; Li ZR; Shen D; Zheng Y; Zheng YC; Liu HM
Eur J Med Chem; 2023 Nov; 260():115732. PubMed ID: 37651876
[TBL] [Abstract][Full Text] [Related]
8. A first-in-class inhibitor, MLN4924 (pevonedistat), induces cell-cycle arrest, senescence, and apoptosis in human renal cell carcinoma by suppressing UBE2M-dependent neddylation modification.
Xu B; Deng Y; Bi R; Guo H; Shu C; Shah NK; Chang J; Liu G; Du Y; Wei W; Wang C
Cancer Chemother Pharmacol; 2018 Jun; 81(6):1083-1093. PubMed ID: 29667067
[TBL] [Abstract][Full Text] [Related]
9. Neddylation E2 UBE2F Promotes the Survival of Lung Cancer Cells by Activating CRL5 to Degrade NOXA via the K11 Linkage.
Zhou W; Xu J; Li H; Xu M; Chen ZJ; Wei W; Pan Z; Sun Y
Clin Cancer Res; 2017 Feb; 23(4):1104-1116. PubMed ID: 27591266
[No Abstract] [Full Text] [Related]
10. Unique pattern of component gene disruption in the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in serous ovarian cancer.
Martinez VD; Vucic EA; Thu KL; Pikor LA; Hubaux R; Lam WL
Biomed Res Int; 2014; 2014():159459. PubMed ID: 25114896
[TBL] [Abstract][Full Text] [Related]
11. Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer.
Martinez VD; Vucic EA; Pikor LA; Thu KL; Hubaux R; Lam WL
Mol Cancer; 2013 Oct; 12(1):124. PubMed ID: 24138990
[TBL] [Abstract][Full Text] [Related]
12. Targeting Protein Neddylation to Inactivate Cullin-RING Ligases by Gossypol: A Lucky Hit or a New Start?
Yu Q; Sun Y
Drug Des Devel Ther; 2021; 15():1-8. PubMed ID: 33442232
[TBL] [Abstract][Full Text] [Related]
13. Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression.
Kaspar JW; Niture SK; Jaiswal AK
J Cell Sci; 2012 Feb; 125(Pt 4):1027-38. PubMed ID: 22448038
[TBL] [Abstract][Full Text] [Related]
14. Targeting neddylation E2s: a novel therapeutic strategy in cancer.
Zheng YC; Guo YJ; Wang B; Wang C; Mamun MAA; Gao Y; Liu HM
J Hematol Oncol; 2021 Apr; 14(1):57. PubMed ID: 33827629
[TBL] [Abstract][Full Text] [Related]
15. Inactivating UBE2M impacts the DNA damage response and genome integrity involving multiple cullin ligases.
Cukras S; Morffy N; Ohn T; Kee Y
PLoS One; 2014; 9(7):e101844. PubMed ID: 25025768
[TBL] [Abstract][Full Text] [Related]
16. Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes.
Ichikawa T; Li J; Meyer CJ; Janicki JS; Hannink M; Cui T
PLoS One; 2009 Dec; 4(12):e8391. PubMed ID: 20027226
[TBL] [Abstract][Full Text] [Related]
17. Cullin 3 RING E3 ligase inactivation causes NRF2-dependent NADH reductive stress, hepatic lipodystrophy, and systemic insulin resistance.
Gu L; Du Y; Chen J; Hasan MN; Clayton YD; Matye DJ; Friedman JE; Li T
Proc Natl Acad Sci U S A; 2024 Apr; 121(17):e2320934121. PubMed ID: 38630726
[TBL] [Abstract][Full Text] [Related]
18. Neddylation inhibitor MLN4924 suppresses growth and migration of human gastric cancer cells.
Lan H; Tang Z; Jin H; Sun Y
Sci Rep; 2016 Apr; 6():24218. PubMed ID: 27063292
[TBL] [Abstract][Full Text] [Related]
19. Suppression of tumor angiogenesis by targeting the protein neddylation pathway.
Yao WT; Wu JF; Yu GY; Wang R; Wang K; Li LH; Chen P; Jiang YN; Cheng H; Lee HW; Yu J; Qi H; Yu XJ; Wang P; Chu YW; Yang M; Hua ZC; Ying HQ; Hoffman RM; Jeong LS; Jia LJ
Cell Death Dis; 2014 Feb; 5(2):e1059. PubMed ID: 24525735
[TBL] [Abstract][Full Text] [Related]
20. An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance.
Kaspar JW; Jaiswal AK
J Biol Chem; 2010 Jul; 285(28):21349-58. PubMed ID: 20452971
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]