BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

153 related articles for article (PubMed ID: 38280930)

  • 1. Re-expression of epigenetically silenced PTPRR by histone acetylation sensitizes RAS-mutant lung adenocarcinoma to SHP2 inhibition.
    Du T; Hu X; Hou Z; Wang W; You S; Wang M; Ji M; Xue N; Chen X
    Cell Mol Life Sci; 2024 Jan; 81(1):64. PubMed ID: 38280930
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Protein tyrosine phosphatase receptor type R (PTPRR) antagonizes the Wnt signaling pathway in ovarian cancer by dephosphorylating and inactivating β-catenin.
    Wang Y; Cao J; Liu W; Zhang J; Wang Z; Zhang Y; Hou L; Chen S; Hao P; Zhang L; Zhuang M; Yu Y; Li D; Fan G
    J Biol Chem; 2019 Nov; 294(48):18306-18323. PubMed ID: 31653698
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein Tyrosine Phosphatase Non-Receptor 11 (
    Richards CE; Elamin YY; Carr A; Gately K; Rafee S; Cremona M; Hanrahan E; Smyth R; Ryan D; Morgan RK; Kennedy S; Hudson L; Fay J; O'Byrne K; Hennessy BT; Toomey S
    Int J Mol Sci; 2023 Jun; 24(13):. PubMed ID: 37445722
    [No Abstract]   [Full Text] [Related]  

  • 4. Androgen-regulation of the protein tyrosine phosphatase PTPRR activates ERK1/2 signalling in prostate cancer cells.
    Munkley J; Lafferty NP; Kalna G; Robson CN; Leung HY; Rajan P; Elliott DJ
    BMC Cancer; 2015 Jan; 15():9. PubMed ID: 25592066
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of Shp2 suppresses mutant EGFR-induced lung tumors in transgenic mouse model of lung adenocarcinoma.
    Schneeberger VE; Ren Y; Luetteke N; Huang Q; Chen L; Lawrence HR; Lawrence NJ; Haura EB; Koomen JM; Coppola D; Wu J
    Oncotarget; 2015 Mar; 6(8):6191-202. PubMed ID: 25730908
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dioscin overcome TKI resistance in EGFR-mutated lung adenocarcinoma cells via down-regulation of tyrosine phosphatase SHP2 expression.
    Wang YC; Wu DW; Wu TC; Wang L; Chen CY; Lee H
    Int J Biol Sci; 2018; 14(1):47-56. PubMed ID: 29483824
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The protein tyrosine phosphatase receptor type R gene is an early and frequent target of silencing in human colorectal tumorigenesis.
    Menigatti M; Cattaneo E; Sabates-Bellver J; Ilinsky VV; Went P; Buffoli F; Marquez VE; Jiricny J; Marra G
    Mol Cancer; 2009 Dec; 8():124. PubMed ID: 20015382
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Quercetin inhibits the proliferation of multiple myeloma cells by upregulating PTPRR expression.
    Wang H; Yu D; Zhang H; Ma R; Wu H; Zhai H; Wang H; Li J; Li L; Wang Y; Cheng T; Shi J
    Acta Biochim Biophys Sin (Shanghai); 2021 Nov; 53(11):1505-1515. PubMed ID: 34558606
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase.
    Ruess DA; Heynen GJ; Ciecielski KJ; Ai J; Berninger A; Kabacaoglu D; Görgülü K; Dantes Z; Wörmann SM; Diakopoulos KN; Karpathaki AF; Kowalska M; Kaya-Aksoy E; Song L; van der Laan EAZ; López-Alberca MP; Nazaré M; Reichert M; Saur D; Erkan MM; Hopt UT; Sainz B; Birchmeier W; Schmid RM; Lesina M; Algül H
    Nat Med; 2018 Jul; 24(7):954-960. PubMed ID: 29808009
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PTPRR protein tyrosine phosphatase isoforms and locomotion of vesicles and mice.
    Hendriks WJ; Dilaver G; Noordman YE; Kremer B; Fransen JA
    Cerebellum; 2009 Jun; 8(2):80-8. PubMed ID: 19137382
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SHP2E76K mutant promotes lung tumorigenesis in transgenic mice.
    Schneeberger VE; Luetteke N; Ren Y; Berns H; Chen L; Foroutan P; Martinez GV; Haura EB; Chen J; Coppola D; Wu J
    Carcinogenesis; 2014 Aug; 35(8):1717-25. PubMed ID: 24480804
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PTPRR regulates ERK dephosphorylation in depression mice model.
    Li X; Liu Z; Li W; Sun N; Xu Y; Xie Z; Zhang K
    J Affect Disord; 2016 Mar; 193():233-41. PubMed ID: 26773914
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Src homology phosphotyrosyl phosphatase 2 mediates cisplatin-related drug resistance by inhibiting apoptosis and activating the Ras/PI3K/Akt1/survivin pathway in lung cancer cells.
    Tang C; Luo H; Luo D; Yang H; Zhou X
    Oncol Rep; 2018 Feb; 39(2):611-618. PubMed ID: 29207183
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epigenetic silencing of PTPRR activates MAPK signaling, promotes metastasis and serves as a biomarker of invasive cervical cancer.
    Su PH; Lin YW; Huang RL; Liao YP; Lee HY; Wang HC; Chao TK; Chen CK; Chan MW; Chu TY; Yu MH; Lai HC
    Oncogene; 2013 Jan; 32(1):15-26. PubMed ID: 22330137
    [TBL] [Abstract][Full Text] [Related]  

  • 15.
    Valencia-Sama I; Ladumor Y; Kee L; Adderley T; Christopher G; Robinson CM; Kano Y; Ohh M; Irwin MS
    Cancer Res; 2020 Aug; 80(16):3413-3423. PubMed ID: 32586982
    [TBL] [Abstract][Full Text] [Related]  

  • 16. JC-010a, a novel selective SHP2 allosteric inhibitor, overcomes RTK/non-RTK-mediated drug resistance in multiple oncogene-addicted cancers.
    Lu X; Yu R; Li Z; Yang M; Dai J; Liu M
    Cancer Lett; 2024 Feb; 582():216517. PubMed ID: 38101609
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases.
    Chen YN; LaMarche MJ; Chan HM; Fekkes P; Garcia-Fortanet J; Acker MG; Antonakos B; Chen CH; Chen Z; Cooke VG; Dobson JR; Deng Z; Fei F; Firestone B; Fodor M; Fridrich C; Gao H; Grunenfelder D; Hao HX; Jacob J; Ho S; Hsiao K; Kang ZB; Karki R; Kato M; Larrow J; La Bonte LR; Lenoir F; Liu G; Liu S; Majumdar D; Meyer MJ; Palermo M; Perez L; Pu M; Price E; Quinn C; Shakya S; Shultz MD; Slisz J; Venkatesan K; Wang P; Warmuth M; Williams S; Yang G; Yuan J; Zhang JH; Zhu P; Ramsey T; Keen NJ; Sellers WR; Stams T; Fortin PD
    Nature; 2016 Jul; 535(7610):148-52. PubMed ID: 27362227
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Src-homology 2 domain-containing tyrosine phosphatase 2 promotes oral cancer invasion and metastasis.
    Wang HC; Chiang WF; Huang HH; Shen YY; Chiang HC
    BMC Cancer; 2014 Jun; 14():442. PubMed ID: 24931737
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting SHP2 for EGFR inhibitor resistant non-small cell lung carcinoma.
    Xu J; Zeng LF; Shen W; Turchi JJ; Zhang ZY
    Biochem Biophys Res Commun; 2013 Oct; 439(4):586-90. PubMed ID: 24041688
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Noonan syndrome-causing SHP2 mutants inhibit insulin-like growth factor 1 release via growth hormone-induced ERK hyperactivation, which contributes to short stature.
    De Rocca Serra-Nédélec A; Edouard T; Tréguer K; Tajan M; Araki T; Dance M; Mus M; Montagner A; Tauber M; Salles JP; Valet P; Neel BG; Raynal P; Yart A
    Proc Natl Acad Sci U S A; 2012 Mar; 109(11):4257-62. PubMed ID: 22371576
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.