BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 38285887)

  • 1. Targeting G9a/DNMT1 methyltransferase activity impedes IGF2-mediated survival in hepatoblastoma.
    Demir S; Razizadeh N; Indersie E; Branchereau S; Cairo S; Kappler R
    Hepatol Commun; 2024 Feb; 8(2):. PubMed ID: 38285887
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dual Targeting of Histone Methyltransferase G9a and DNA-Methyltransferase 1 for the Treatment of Experimental Hepatocellular Carcinoma.
    Bárcena-Varela M; Caruso S; Llerena S; Álvarez-Sola G; Uriarte I; Latasa MU; Urtasun R; Rebouissou S; Alvarez L; Jimenez M; Santamaría E; Rodriguez-Ortigosa C; Mazza G; Rombouts K; San José-Eneriz E; Rabal O; Agirre X; Iraburu M; Santos-Laso A; Banales JM; Zucman-Rossi J; Prósper F; Oyarzabal J; Berasain C; Ávila MA; Fernández-Barrena MG
    Hepatology; 2019 Feb; 69(2):587-603. PubMed ID: 30014490
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma.
    Colyn L; Bárcena-Varela M; Álvarez-Sola G; Latasa MU; Uriarte I; Santamaría E; Herranz JM; Santos-Laso A; Arechederra M; Ruiz de Gauna M; Aspichueta P; Canale M; Casadei-Gardini A; Francesconi M; Carotti S; Morini S; Nelson LJ; Iraburu MJ; Chen C; Sangro B; Marin JJG; Martinez-Chantar ML; Banales JM; Arnes-Benito R; Huch M; Patino JM; Dar AA; Nosrati M; Oyarzábal J; Prósper F; Urman J; Cubero FJ; Trautwein C; Berasain C; Fernandez-Barrena MG; Avila MA
    Hepatology; 2021 Jun; 73(6):2380-2396. PubMed ID: 33222246
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Overexpression of
    Beck A; Trippel F; Wagner A; Joppien S; Felle M; Vokuhl C; Schwarzmayr T; Strom TM; von Schweinitz D; Längst G; Kappler R
    Clin Epigenetics; 2018; 10():27. PubMed ID: 29507645
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of IGF2 as Genomic Driver and Actionable Therapeutic Target in Hepatoblastoma.
    Abril-Fornaguera J; Torrens L; Andreu-Oller C; Carrillo-Reixach J; Rialdi A; Balaseviciute U; Pinyol R; Montironi C; Haber PK; Del Río-Álvarez Á; Domingo-Sàbat M; Royo L; Akers NK; Willoughby CE; Peix J; Torres-Martin M; Puigvehi M; Cairo S; Childs M; Maibach R; Alaggio R; Czauderna P; Morland B; Losic B; Mazzaferro V; Guccione E; Sia D; Armengol C; Llovet JM
    Mol Cancer Ther; 2023 Apr; 22(4):485-498. PubMed ID: 36780225
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification and experimental validation of druggable epigenetic targets in hepatoblastoma.
    Clavería-Cabello A; Herranz JM; Latasa MU; Arechederra M; Uriarte I; Pineda-Lucena A; Prosper F; Berraondo P; Alonso C; Sangro B; García Marin JJ; Martinez-Chantar ML; Ciordia S; Corrales FJ; Francalanci P; Alaggio R; Zucman-Rossi J; Indersie E; Cairo S; Domingo-Sàbat M; Zanatto L; Sancho-Bru P; Armengol C; Berasain C; Fernandez-Barrena MG; Avila MA
    J Hepatol; 2023 Oct; 79(4):989-1005. PubMed ID: 37302584
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The Ubiquitin-like with PHD and Ring Finger Domains 1 (UHRF1)/DNA Methyltransferase 1 (DNMT1) Axis Is a Primary Regulator of Cell Senescence.
    Jung HJ; Byun HO; Jee BA; Min S; Jeoun UW; Lee YK; Seo Y; Woo HG; Yoon G
    J Biol Chem; 2017 Mar; 292(9):3729-3739. PubMed ID: 28100769
    [TBL] [Abstract][Full Text] [Related]  

  • 8. UHRF1 is associated with epigenetic silencing of BRCA1 in sporadic breast cancer.
    Jin W; Chen L; Chen Y; Xu SG; Di GH; Yin WJ; Wu J; Shao ZM
    Breast Cancer Res Treat; 2010 Sep; 123(2):359-73. PubMed ID: 19943104
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Essential Role of DNA Methyltransferase 1-mediated Transcription of Insulin-like Growth Factor 2 in Resistance to Histone Deacetylase Inhibitors.
    Min HY; Lee SC; Woo JK; Jung HJ; Park KH; Jeong HM; Hyun SY; Cho J; Lee W; Park JE; Kwon SJ; Lee HJ; Ni X; Shin YK; Johnson FM; Duvic M; Lee HY
    Clin Cancer Res; 2017 Mar; 23(5):1299-1311. PubMed ID: 27582487
    [No Abstract]   [Full Text] [Related]  

  • 10. Cross-talk Between Histone and DNA Methylation Mediates Bone Loss in Hind Limb Unloading.
    Li B; Zhao J; Ma J; Chen W; Zhou C; Wei W; Li S; Li G; Xin G; Zhang Y; Liu J; Wang Y; Ma X
    J Bone Miner Res; 2021 May; 36(5):956-967. PubMed ID: 33465813
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The novel mTOR inhibitor Torin-2 induces autophagy and downregulates the expression of UHRF1 to suppress hepatocarcinoma cell growth.
    Wang C; Wang X; Su Z; Fei H; Liu X; Pan Q
    Oncol Rep; 2015 Oct; 34(4):1708-16. PubMed ID: 26239364
    [TBL] [Abstract][Full Text] [Related]  

  • 12. UHRF1 binds G9a and participates in p21 transcriptional regulation in mammalian cells.
    Kim JK; Estève PO; Jacobsen SE; Pradhan S
    Nucleic Acids Res; 2009 Feb; 37(2):493-505. PubMed ID: 19056828
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A role for LSH in facilitating DNA methylation by DNMT1 through enhancing UHRF1 chromatin association.
    Han M; Li J; Cao Y; Huang Y; Li W; Zhu H; Zhao Q; Han JJ; Wu Q; Li J; Feng J; Wong J
    Nucleic Acids Res; 2020 Dec; 48(21):12116-12134. PubMed ID: 33170271
    [TBL] [Abstract][Full Text] [Related]  

  • 14. DNA methylation requires a DNMT1 ubiquitin interacting motif (UIM) and histone ubiquitination.
    Qin W; Wolf P; Liu N; Link S; Smets M; La Mastra F; Forné I; Pichler G; Hörl D; Fellinger K; Spada F; Bonapace IM; Imhof A; Harz H; Leonhardt H
    Cell Res; 2015 Aug; 25(8):911-29. PubMed ID: 26065575
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thymoquinone Is a Multitarget Single Epidrug That Inhibits the UHRF1 Protein Complex.
    Abdullah O; Omran Z; Hosawi S; Hamiche A; Bronner C; Alhosin M
    Genes (Basel); 2021 Apr; 12(5):. PubMed ID: 33922029
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1.
    Zhang H; Gao Q; Tan S; You J; Lyu C; Zhang Y; Han M; Chen Z; Li J; Wang H; Liao L; Qin J; Li J; Wong J
    Nucleic Acids Res; 2019 Sep; 47(17):9053-9068. PubMed ID: 31400111
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The finger loop of the SRA domain in the E3 ligase UHRF1 is a regulator of ubiquitin targeting and is required for the maintenance of DNA methylation.
    Vaughan RM; Rothbart SB; Dickson BM
    J Biol Chem; 2019 Oct; 294(43):15724-15732. PubMed ID: 31481468
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein.
    Cheng J; Yang Y; Fang J; Xiao J; Zhu T; Chen F; Wang P; Li Z; Yang H; Xu Y
    J Biol Chem; 2013 Jan; 288(2):1329-39. PubMed ID: 23161542
    [TBL] [Abstract][Full Text] [Related]  

  • 19. S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenance.
    Zhang J; Gao Q; Li P; Liu X; Jia Y; Wu W; Li J; Dong S; Koseki H; Wong J
    Cell Res; 2011 Dec; 21(12):1723-39. PubMed ID: 22064703
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Non-canonical functions of UHRF1 maintain DNA methylation homeostasis in cancer cells.
    Yamaguchi K; Chen X; Rodgers B; Miura F; Bashtrykov P; Bonhomme F; Salinas-Luypaert C; Haxholli D; Gutekunst N; Aygenli BÖ; Ferry L; Kirsh O; Laisné M; Scelfo A; Ugur E; Arimondo PB; Leonhardt H; Kanemaki MT; Bartke T; Fachinetti D; Jeltsch A; Ito T; Defossez PA
    Nat Commun; 2024 Apr; 15(1):2960. PubMed ID: 38580649
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.