BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 38290979)

  • 1. Oxidative stress accelerates intestinal tumorigenesis by enhancing 8-oxoguanine-mediated mutagenesis in MUTYH-deficient mice.
    Ohno M; Takano N; Hidaka K; Sasaki F; Yamauchi K; Aoki Y; Nohmi T; Nakabeppu Y; Nakatsu Y; Tsuzuki T
    Genome Res; 2024 Feb; 34(1):47-56. PubMed ID: 38290979
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Abnormality in Wnt signaling is causatively associated with oxidative stress-induced intestinal tumorigenesis in MUTYH-null mice.
    Isoda T; Nakatsu Y; Yamauchi K; Piao J; Yao T; Honda H; Nakabeppu Y; Tsuzuki T
    Int J Biol Sci; 2014; 10(8):940-7. PubMed ID: 25170306
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional cooperation of Ogg1 and Mutyh in preventing G: C-->T: a transversions in mice.
    Isogawa A
    Fukuoka Igaku Zasshi; 2004 Jan; 95(1):17-30. PubMed ID: 15031996
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MUTYH-null mice are susceptible to spontaneous and oxidative stress induced intestinal tumorigenesis.
    Sakamoto K; Tominaga Y; Yamauchi K; Nakatsu Y; Sakumi K; Yoshiyama K; Egashira A; Kura S; Yao T; Tsuneyoshi M; Maki H; Nakabeppu Y; Tsuzuki T
    Cancer Res; 2007 Jul; 67(14):6599-604. PubMed ID: 17638869
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Specific Mutational Signature Associated with DNA 8-Oxoguanine Persistence in MUTYH-defective Colorectal Cancer.
    Viel A; Bruselles A; Meccia E; Fornasarig M; Quaia M; Canzonieri V; Policicchio E; Urso ED; Agostini M; Genuardi M; Lucci-Cordisco E; Venesio T; Martayan A; Diodoro MG; Sanchez-Mete L; Stigliano V; Mazzei F; Grasso F; Giuliani A; Baiocchi M; Maestro R; Giannini G; Tartaglia M; Alexandrov LB; Bignami M
    EBioMedicine; 2017 Jun; 20():39-49. PubMed ID: 28551381
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair.
    Sheng Z; Oka S; Tsuchimoto D; Abolhassani N; Nomaru H; Sakumi K; Yamada H; Nakabeppu Y
    J Clin Invest; 2012 Dec; 122(12):4344-61. PubMed ID: 23143307
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Repair of 8-oxo-7,8-dihydroguanine in prokaryotic and eukaryotic cells: Properties and biological roles of the Fpg and OGG1 DNA N-glycosylases.
    Boiteux S; Coste F; Castaing B
    Free Radic Biol Med; 2017 Jun; 107():179-201. PubMed ID: 27903453
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA glycosylase encoded by MUTYH functions as a molecular switch for programmed cell death under oxidative stress to suppress tumorigenesis.
    Oka S; Nakabeppu Y
    Cancer Sci; 2011 Apr; 102(4):677-82. PubMed ID: 21235684
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oxidative-stress-driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassium bromate.
    Aoki Y; Taniguchi Y; Matsumoto M; Matsumoto M; Ohno M; Masumura K; Sasaki S; Tsuzuki T; Yamamoto M; Nohmi T
    Mutat Res Genet Toxicol Environ Mutagen; 2020; 850-851():503136. PubMed ID: 32247553
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Repair of 8-oxoG:A mismatches by the MUTYH glycosylase: Mechanism, metals and medicine.
    Banda DM; Nuñez NN; Burnside MA; Bradshaw KM; David SS
    Free Radic Biol Med; 2017 Jun; 107():202-215. PubMed ID: 28087410
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Single molecule glycosylase studies with engineered 8-oxoguanine DNA damage sites show functional defects of a MUTYH polyposis variant.
    Nelson SR; Kathe SD; Hilzinger TS; Averill AM; Warshaw DM; Wallace SS; Lee AJ
    Nucleic Acids Res; 2019 Apr; 47(6):3058-3071. PubMed ID: 30698731
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids.
    Nakabeppu Y; Sakumi K; Sakamoto K; Tsuchimoto D; Tsuzuki T; Nakatsu Y
    Biol Chem; 2006 Apr; 387(4):373-9. PubMed ID: 16606334
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Oxidative stress induces different tissue dependent effects on Mutyh-deficient mice.
    Chen J; Huang Z; Wu X; Kang J; Ren Y; Gao W; Lu X; Wang J; Ding W; Nakabeppu Y; Fan Y; Wang Y
    Free Radic Biol Med; 2019 Nov; 143():482-493. PubMed ID: 31505270
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Defects in 8-oxo-guanine repair pathway cause high frequency of C > A substitutions in neuroblastoma.
    van den Boogaard ML; Oka R; Hakkert A; Schild L; Ebus ME; van Gerven MR; Zwijnenburg DA; Molenaar P; Hoyng LL; Dolman MEM; Essing AHW; Koopmans B; Helleday T; Drost J; van Boxtel R; Versteeg R; Koster J; Molenaar JJ
    Proc Natl Acad Sci U S A; 2021 Sep; 118(36):. PubMed ID: 34479993
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mismatch repair deficient mice show susceptibility to oxidative stress-induced intestinal carcinogenesis.
    Piao J; Nakatsu Y; Ohno M; Taguchi K; Tsuzuki T
    Int J Biol Sci; 2013; 10(1):73-9. PubMed ID: 24391453
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesis.
    Grasso F; Di Meo S; De Luca G; Pasquini L; Rossi S; Boirivant M; Biffoni M; Bignami M; Di Carlo E
    Oncotarget; 2015 Aug; 6(23):19671-84. PubMed ID: 26109431
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Impaired suppressive activities of human MUTYH variant proteins against oxidative mutagenesis.
    Shinmura K; Goto M; Tao H; Matsuura S; Matsuda T; Sugimura H
    World J Gastroenterol; 2012 Dec; 18(47):6935-42. PubMed ID: 23322991
    [TBL] [Abstract][Full Text] [Related]  

  • 18. MTH1 as a nucleotide pool sanitizing enzyme: Friend or foe?
    Nakabeppu Y; Ohta E; Abolhassani N
    Free Radic Biol Med; 2017 Jun; 107():151-158. PubMed ID: 27833032
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Possible cause of G-C-->C-G transversion mutation by guanine oxidation product, imidazolone.
    Kino K; Sugiyama H
    Chem Biol; 2001 Apr; 8(4):369-78. PubMed ID: 11325592
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis.
    Tsuzuki T; Nakatsu Y; Nakabeppu Y
    Cancer Sci; 2007 Apr; 98(4):465-70. PubMed ID: 17425590
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.