195 related articles for article (PubMed ID: 38294341)
1. PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin.
Lucena-Agell D; Guillén MJ; Matesanz R; Álvarez-Bernad B; Hortigüela R; Avilés P; Martínez-Díez M; Santamaría-Núñez G; Contreras J; Plaza-Menacho I; Giménez-Abián JF; Oliva MA; Cuevas C; Díaz JF
J Med Chem; 2024 Feb; 67(4):2619-2630. PubMed ID: 38294341
[TBL] [Abstract][Full Text] [Related]
2. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
Yan J; Pang Y; Sheng J; Wang Y; Chen J; Hu J; Huang L; Li X
Biochem Pharmacol; 2015 Sep; 97(1):51-61. PubMed ID: 26212540
[TBL] [Abstract][Full Text] [Related]
3. Design, synthesis and biological evaluation of a novel tubulin inhibitor 7a3 targeting the colchicine binding site.
Lai Q; Wang Y; Wang R; Lai W; Tang L; Tao Y; Liu Y; Zhang R; Huang L; Xiang H; Zeng S; Gou L; Chen H; Yao Y; Yang J
Eur J Med Chem; 2018 Aug; 156():162-179. PubMed ID: 30006162
[TBL] [Abstract][Full Text] [Related]
4. Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site.
Lin S; Du T; Zhang J; Wu D; Tian H; Zhang K; Jiang L; Lu D; Sheng L; Li Y; Ji M; Chen X; Xu H
J Med Chem; 2022 Dec; 65(24):16372-16391. PubMed ID: 36511661
[TBL] [Abstract][Full Text] [Related]
5. A novel tubulin inhibitor, 6h, suppresses tumor-associated angiogenesis and shows potent antitumor activity against non-small cell lung cancers.
Liu Z; Huang L; Zhou T; Chang X; Yang Y; Shi Y; Hao M; Li Z; Wu Y; Guan Q; Zhang W; Zuo D
J Biol Chem; 2022 Jul; 298(7):102063. PubMed ID: 35618020
[TBL] [Abstract][Full Text] [Related]
6. Discover 4β-NH-(6-aminoindole)-4-desoxy-podophyllotoxin with nanomolar-potency antitumor activity by improving the tubulin binding affinity on the basis of a potential binding site nearby colchicine domain.
Zhao W; He L; Xiang TL; Tang YJ
Eur J Med Chem; 2019 May; 170():73-86. PubMed ID: 30878833
[TBL] [Abstract][Full Text] [Related]
7. The Design, Synthesis, and Biological Activities of Pyrrole-Based Carboxamides: The Novel Tubulin Inhibitors Targeting the Colchicine-Binding Site.
Boichuk S; Galembikova A; Syuzov K; Dunaev P; Bikinieva F; Aukhadieva A; Zykova S; Igidov N; Gankova K; Novikova M; Kopnin P
Molecules; 2021 Sep; 26(19):. PubMed ID: 34641324
[TBL] [Abstract][Full Text] [Related]
8. Discovery of Novel
Leng J; Zhao Y; Sheng P; Xia Y; Chen T; Zhao S; Xie S; Yan X; Wang X; Yin Y; Kong L
J Med Chem; 2022 Dec; 65(24):16774-16800. PubMed ID: 36471625
[TBL] [Abstract][Full Text] [Related]
9. Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance.
Cheng B; Zhu G; Meng L; Wu G; Chen Q; Ma S
Eur J Med Chem; 2022 Jan; 228():113930. PubMed ID: 34794817
[TBL] [Abstract][Full Text] [Related]
10. A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity.
Du T; Lin S; Ji M; Xue N; Liu Y; Zhang Z; Zhang K; Zhang J; Zhang Y; Wang Q; Sheng L; Li Y; Lu D; Chen X; Xu H
Cancer Lett; 2020 Dec; 495():22-32. PubMed ID: 32931884
[TBL] [Abstract][Full Text] [Related]
11. Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.
Liu YN; Wang JJ; Ji YT; Zhao GD; Tang LQ; Zhang CM; Guo XL; Liu ZP
J Med Chem; 2016 Jun; 59(11):5341-55. PubMed ID: 27172319
[TBL] [Abstract][Full Text] [Related]
12. Simple monocyclic pyrimidine analogs as microtubule targeting agents binding to the colchicine site.
Choudhary S; Kaku K; Robles AJ; Hamel E; Mooberry SL; Gangjee A
Bioorg Med Chem; 2023 Mar; 82():117217. PubMed ID: 36889150
[TBL] [Abstract][Full Text] [Related]
13. A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins.
Povedano JM; Rallabandi R; Bai X; Ye X; Liou J; Chen H; Kim J; Xie Y; Posner B; Rice L; De Brabander JK; McFadden DG
J Med Chem; 2020 Nov; 63(22):14054-14066. PubMed ID: 33180487
[TBL] [Abstract][Full Text] [Related]
14. Recent advances in research of colchicine binding site inhibitors and their interaction modes with tubulin.
Sun K; Sun Z; Zhao F; Shan G; Meng Q
Future Med Chem; 2021 May; 13(9):839-858. PubMed ID: 33821673
[TBL] [Abstract][Full Text] [Related]
15. The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization.
Prota AE; Danel F; Bachmann F; Bargsten K; Buey RM; Pohlmann J; Reinelt S; Lane H; Steinmetz MO
J Mol Biol; 2014 Apr; 426(8):1848-60. PubMed ID: 24530796
[TBL] [Abstract][Full Text] [Related]
16. Design and discovery of new antiproliferative 1,2,4-triazin-3(2H)-ones as tubulin polymerization inhibitors targeting colchicine binding site.
Eissa IH; Dahab MA; Ibrahim MK; Alsaif NA; Alanazi AZ; Eissa SI; Mehany ABM; Beauchemin AM
Bioorg Chem; 2021 Jul; 112():104965. PubMed ID: 34020238
[TBL] [Abstract][Full Text] [Related]
17. Recent Advances in Heterocyclic Tubulin Inhibitors Targeting the Colchicine Binding Site.
Wu X; Wang Q; Li W
Anticancer Agents Med Chem; 2016; 16(10):1325-38. PubMed ID: 26899186
[TBL] [Abstract][Full Text] [Related]
18. An update on the recent advances and discovery of novel tubulin colchicine binding inhibitors.
Weng H; Li J; Zhu H; Carver Wong KF; Zhu Z; Xu J
Future Med Chem; 2023 Jan; 15(1):73-95. PubMed ID: 36756851
[TBL] [Abstract][Full Text] [Related]
19. Targeting Tubulin-colchicine Site for Cancer Therapy: Inhibitors, Antibody- Drug Conjugates and Degradation Agents.
Duan Y; Liu W; Tian L; Mao Y; Song C
Curr Top Med Chem; 2019; 19(15):1289-1304. PubMed ID: 31210108
[TBL] [Abstract][Full Text] [Related]
20. Combined Molecular Docking, 3D-QSAR, and Pharmacophore Model: Design of Novel Tubulin Polymerization Inhibitors by Binding to Colchicine-binding Site.
Li DD; Qin YJ; Zhang X; Yin Y; Zhu HL; Zhao LG
Chem Biol Drug Des; 2015 Oct; 86(4):731-45. PubMed ID: 25711282
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
