BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 38305404)

  • 1. Design, Virtual Screening, Molecular Docking, ADME and Cytotoxicity Studies of 1,3,5-Triazine Containing Heterocyclic Scaffolds as Selective BRAF Monomeric, Homo and Heterodimeric Inhibitors.
    Singh AK; Sreelakshmi P; Pathak P; Kumar A; Singh H; Yadav JP; Verma A; Grishina M; Kumar P
    Comb Chem High Throughput Screen; 2024 Jan; ():. PubMed ID: 38305404
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The first small molecules capable of strongly suppressing proliferation of cancer cells harboring BRAF class I/II/III mutations.
    Choi SH; Shin I; Kim N; Nam Y; Sim T
    Biochem Biophys Res Commun; 2020 Nov; 532(2):315-320. PubMed ID: 32873393
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Challenges and Opportunities in the Crusade of BRAF Inhibitors: From 2002 to 2022.
    Singh AK; Sonawane P; Kumar A; Singh H; Naumovich V; Pathak P; Grishina M; Khalilullah H; Jaremko M; Emwas AH; Verma A; Kumar P
    ACS Omega; 2023 Aug; 8(31):27819-27844. PubMed ID: 37576670
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting oncogenic Raf protein-serine/threonine kinases in human cancers.
    Roskoski R
    Pharmacol Res; 2018 Sep; 135():239-258. PubMed ID: 30118796
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dabrafenib for the treatment of BRAF V600-positive melanoma: a safety evaluation.
    Rutkowski P; Blank C
    Expert Opin Drug Saf; 2014 Sep; 13(9):1249-58. PubMed ID: 25014231
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Classifying BRAF alterations in cancer: new rational therapeutic strategies for actionable mutations.
    Dankner M; Rose AAN; Rajkumar S; Siegel PM; Watson IR
    Oncogene; 2018 Jun; 37(24):3183-3199. PubMed ID: 29540830
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A Rare p.T599dup BRAF Mutant NSCLC in a Non-Smoker.
    Turshudzhyan A; Vredenburgh J
    Curr Oncol; 2020 Dec; 28(1):196-202. PubMed ID: 33704186
    [TBL] [Abstract][Full Text] [Related]  

  • 8. RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling.
    Yao Z; Gao Y; Su W; Yaeger R; Tao J; Na N; Zhang Y; Zhang C; Rymar A; Tao A; Timaul NM; Mcgriskin R; Outmezguine NA; Zhao H; Chang Q; Qeriqi B; Barbacid M; de Stanchina E; Hyman DM; Bollag G; Rosen N
    Nat Med; 2019 Feb; 25(2):284-291. PubMed ID: 30559419
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BRAF Mutations and the Utility of RAF and MEK Inhibitors in Primary Brain Tumors.
    Schreck KC; Grossman SA; Pratilas CA
    Cancers (Basel); 2019 Aug; 11(9):. PubMed ID: 31466300
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of novel natural drug candidates against BRAF mutated carcinoma; An integrative in-silico structure-based pharmacophore modeling and virtual screening process.
    Dain Md Opo FA; Alsaiari AA; Rahman Molla MH; Ahmed Sumon MA; Yaghmour KA; Ahammad F; Mohammad F; Simal-Gandara J
    Front Chem; 2022; 10():986376. PubMed ID: 36267655
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel and Potent Small Molecules against Melanoma Harboring BRAF Class I/II/III Mutants for Overcoming Drug Resistance.
    Kim N; Shin I; Lee J; Jeon E; Kim Y; Ryu S; Ju E; Cho W; Sim T
    Int J Mol Sci; 2021 Apr; 22(7):. PubMed ID: 33917428
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Network indirect comparison of 3 BRAF + MEK inhibitors for the treatment of advanced BRAF mutated melanoma.
    Consoli F; Bersanelli M; Perego G; Grisanti S; Merelli B; Berruti A; Petrelli F
    Clin Transl Oncol; 2020 Jun; 22(6):900-907. PubMed ID: 31555967
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combined RAF and MEK Inhibition to Treat Activated Non-V600 BRAF-Altered Advanced Cancers.
    Rustgi N; Maria A; Toumbacaris N; Zhao H; Kargus K; Bryant M; Waksmundzki A; Aricescu I; Lefkowitz RA; Li BT; Chou J; Capanu M; de Stanchina E; Misale S; Shia J; Yaeger R
    Oncologist; 2024 Jan; 29(1):15-24. PubMed ID: 37616543
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Melanomas with concurrent BRAF non-p.V600 and NF1 loss-of-function mutations are targetable by BRAF/MEK inhibitor combination therapy.
    Rajkumar S; Berry D; Heney KA; Strong C; Ramsay L; Lajoie M; Alkallas R; Nguyen TT; Thomson C; Ahanfeshar-Adams M; Dankner M; Petrella T; Rose AAN; Siegel PM; Watson IR
    Cell Rep; 2022 Apr; 39(1):110634. PubMed ID: 35385748
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Efficacy of Dabrafenib and Trametinib in a Patient with Squamous-Cell Carcinoma, with Mutation p.D594G in
    Grenda A; Krawczyk P; Targowska-Duda KM; Kieszko R; Paśnik I; Milanowski J
    Int J Mol Sci; 2023 Jan; 24(2):. PubMed ID: 36674722
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Successful rechallenge in two patients with BRAF-V600-mutant melanoma who experienced previous progression during treatment with a selective BRAF inhibitor.
    Seghers AC; Wilgenhof S; Lebbé C; Neyns B
    Melanoma Res; 2012 Dec; 22(6):466-72. PubMed ID: 22584957
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Triplet combination of BRAF, MEK and PD-1/PD-L1 blockade in melanoma: the more the better?
    Trojaniello C; Vitale MG; Ascierto PA
    Curr Opin Oncol; 2021 Mar; 33(2):133-138. PubMed ID: 33399314
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Encorafenib plus binimetinib in patients with
    Riely GJ; Ahn MJ; Felip E; Ramalingam SS; Smit EF; Tsao AS; Alcasid A; Usari T; Wissel PS; Wilner KD; Johnson BE
    Future Oncol; 2022 Mar; 18(7):781-791. PubMed ID: 34918546
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Encorafenib and binimetinib for the treatment of BRAF V600E/K-mutated melanoma.
    Rose AAN
    Drugs Today (Barc); 2019 Apr; 55(4):247-264. PubMed ID: 31050693
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Non-V600 BRAF mutations recurrently found in lung cancer predict sensitivity to the combination of Trametinib and Dabrafenib.
    Noeparast A; Teugels E; Giron P; Verschelden G; De Brakeleer S; Decoster L; De Grève J
    Oncotarget; 2017 Sep; 8(36):60094-60108. PubMed ID: 28947956
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.