BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 38306418)

  • 1. Precise CRISPR-Cas9 gene repair in autologous memory T cells to treat familial hemophagocytic lymphohistiocytosis.
    Li X; Wirtz T; Weber T; Lebedin M; Lowenstein ED; Sommermann T; Zach A; Yasuda T; de la Rosa K; Chu VT; Schulte JH; Müller I; Kocks C; Rajewsky K
    Sci Immunol; 2024 Feb; 9(92):eadi0042. PubMed ID: 38306418
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Retroviral
    Dettmer V; Bloom K; Gross M; Weissert K; Aichele P; Ehl S; Cathomen T
    Hum Gene Ther; 2019 Aug; 30(8):975-984. PubMed ID: 31032638
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Correlation between phenotypic heterogeneity and gene mutational characteristics in familial hemophagocytic lymphohistiocytosis (FHL).
    Ueda I; Ishii E; Morimoto A; Ohga S; Sako M; Imashuku S
    Pediatr Blood Cancer; 2006 Apr; 46(4):482-8. PubMed ID: 16365863
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Founder effects in two predominant intronic mutations of UNC13D, c.118-308C>T and c.754-1G>C underlie the unusual predominance of type 3 familial hemophagocytic lymphohistiocytosis (FHL3) in Korea.
    Seo JY; Song JS; Lee KO; Won HH; Kim JW; Kim SH; Lee SH; Yoo KH; Sung KW; Koo HH; Kang HJ; Shin HY; Ahn HS; Han DK; Kook H; Hwang TJ; Lyu CJ; Lee MJ; Kim JY; Park SS; Lim YT; Kim BE; Koh KN; Im HJ; Seo JJ; Kim HJ;
    Ann Hematol; 2013 Mar; 92(3):357-64. PubMed ID: 23180437
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A.
    Zur Stadt U; Beutel K; Kolberg S; Schneppenheim R; Kabisch H; Janka G; Hennies HC
    Hum Mutat; 2006 Jan; 27(1):62-8. PubMed ID: 16278825
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Gene editing of hematopoietic stem cells restores T-cell response in familial hemophagocytic lymphohistiocytosis.
    Dettmer-Monaco V; Weißert K; Ammann S; Monaco G; Lei L; Gräßel L; Rhiel M; Rositzka J; Kaufmann MM; Geiger K; Andrieux G; Lao J; Thoulass G; Schell C; Boerries M; Illert AL; Cornu TI; Ehl S; Aichele P; Cathomen T
    J Allergy Clin Immunol; 2024 Jan; 153(1):243-255.e14. PubMed ID: 37595758
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Subtypes of familial hemophagocytic lymphohistiocytosis in Japan based on genetic and functional analyses of cytotoxic T lymphocytes.
    Nagai K; Yamamoto K; Fujiwara H; An J; Ochi T; Suemori K; Yasumi T; Tauchi H; Koh K; Sato M; Morimoto A; Heike T; Ishii E; Yasukawa M
    PLoS One; 2010 Nov; 5(11):e14173. PubMed ID: 21152410
    [TBL] [Abstract][Full Text] [Related]  

  • 8. UNC13D is the predominant causative gene with recurrent splicing mutations in Korean patients with familial hemophagocytic lymphohistiocytosis.
    Yoon HS; Kim HJ; Yoo KH; Sung KW; Koo HH; Kang HJ; Shin HY; Ahn HS; Kim JY; Lim YT; Bae KW; Lee KO; Shin JS; Lee ST; Chung HS; Kim SH; Park CJ; Chi HS; Im HJ; Seo JJ
    Haematologica; 2010 Apr; 95(4):622-6. PubMed ID: 20015888
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Clinical and Genetic Analysis of Nine Suspected Familial Haemophagocytic Lymphohistiocytosis Patients for MUNC13-4 Deficiency and Introducing Four Novel Mutations in UNC13D.
    Vahidi M; Badalzadeh M; Jannesar M; Mazinani M; Fazlollahi MR; Khodayari Namini N; Houshmand M; Hamidieh AA; Moradi L; Pourpak Z; Moin M
    Iran J Allergy Asthma Immunol; 2019 Oct; 18(5):487-492. PubMed ID: 32245292
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Screening the PRF1, UNC13D, STX11, SH2D1A, XIAP, and ITK gene mutations in Chinese children with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.
    Zhizhuo H; Junmei X; Yuelin S; Qiang Q; Chunyan L; Zhengde X; Kunling S
    Pediatr Blood Cancer; 2012 Mar; 58(3):410-4. PubMed ID: 21674762
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genetic predisposition to hemophagocytic lymphohistiocytosis: Report on 500 patients from the Italian registry.
    Cetica V; Sieni E; Pende D; Danesino C; De Fusco C; Locatelli F; Micalizzi C; Putti MC; Biondi A; Fagioli F; Moretta L; Griffiths GM; Luzzatto L; Aricò M
    J Allergy Clin Immunol; 2016 Jan; 137(1):188-196.e4. PubMed ID: 26342526
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of a large UNC13D gene duplication in a patient with familial hemophagocytic lymphohistiocytosis type 3.
    Hiejima E; Shibata H; Yasumi T; Shimodera S; Hori M; Izawa K; Kawai T; Matsuoka M; Kojima Y; Ohara A; Nishikomori R; Ohara O; Heike T
    Clin Immunol; 2018 Jun; 191():63-66. PubMed ID: 29596912
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Patients with Griscelli syndrome and normal pigmentation identify RAB27A mutations that selectively disrupt MUNC13-4 binding.
    Cetica V; Hackmann Y; Grieve S; Sieni E; Ciambotti B; Coniglio ML; Pende D; Gilmour K; Romagnoli P; Griffiths GM; Aricò M
    J Allergy Clin Immunol; 2015 May; 135(5):1310-8.e1. PubMed ID: 25312756
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases.
    Rohr J; Beutel K; Maul-Pavicic A; Vraetz T; Thiel J; Warnatz K; Bondzio I; Gross-Wieltsch U; Schündeln M; Schütz B; Woessmann W; Groll AH; Strahm B; Pagel J; Speckmann C; Janka G; Griffiths G; Schwarz K; zur Stadt U; Ehl S
    Haematologica; 2010 Dec; 95(12):2080-7. PubMed ID: 20823128
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Munc13-4 deficiency with CD5 downregulation on activated CD8+ T cells.
    Wada T; Yasumi T; Toma T; Hori M; Maeda S; Umeda K; Heike T; Adachi S; Usami I; Yachie A
    Pediatr Int; 2014 Aug; 56(4):605-8. PubMed ID: 25252047
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel Munc13-4 mutations in children and young adult patients with haemophagocytic lymphohistiocytosis.
    Santoro A; Cannella S; Bossi G; Gallo F; Trizzino A; Pende D; Dieli F; Bruno G; Stinchcombe JC; Micalizzi C; De Fusco C; Danesino C; Moretta L; Notarangelo LD; Griffiths GM; Aricò M
    J Med Genet; 2006 Dec; 43(12):953-60. PubMed ID: 16825436
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Angeborene hämophagozytische Lymphohistiozytose (HLH).
    Pachlopnik Schmid J; de Saint Basile G
    Klin Padiatr; 2010 Nov; 222(6):345-50. PubMed ID: 20458667
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic subtypes of familial hemophagocytic lymphohistiocytosis: correlations with clinical features and cytotoxic T lymphocyte/natural killer cell functions.
    Ishii E; Ueda I; Shirakawa R; Yamamoto K; Horiuchi H; Ohga S; Furuno K; Morimoto A; Imayoshi M; Ogata Y; Zaitsu M; Sako M; Koike K; Sakata A; Takada H; Hara T; Imashuku S; Sasazuki T; Yasukawa M
    Blood; 2005 May; 105(9):3442-8. PubMed ID: 15632205
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Down-regulation of CD5 expression on activated CD8+ T cells in familial hemophagocytic lymphohistiocytosis with perforin gene mutations.
    Wada T; Sakakibara Y; Nishimura R; Toma T; Ueno Y; Horita S; Tanaka T; Nishi M; Kato K; Yasumi T; Ohara O; Yachie A
    Hum Immunol; 2013 Dec; 74(12):1579-85. PubMed ID: 24051121
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bone marrow derived mesenchymal stem cells ameliorate inflammatory response in an in vitro model of familial hemophagocytic lymphohistiocytosis 2.
    Sevim H; Kocaefe YÇ; Onur MA; Uçkan-Çetinkaya D; Gürpınar ÖA
    Stem Cell Res Ther; 2018 Jul; 9(1):198. PubMed ID: 30021624
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.