These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 38314653)

  • 1. Computational evidences of a misfolding event in an aggregation-prone light chain preceding the formation of the non-native pathogenic dimer.
    Desantis F; Miotto M; Milanetti E; Ruocco G; Di Rienzo L
    Proteins; 2024 Jul; 92(7):797-807. PubMed ID: 38314653
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The CDR1 and Other Regions of Immunoglobulin Light Chains are Hot Spots for Amyloid Aggregation.
    Ruiz-Zamora RA; Guillaumé S; Al-Hilaly YK; Al-Garawi Z; Rodríguez-Alvarez FJ; Zavala-Padilla G; Pérez-Carreón JI; Rodríguez-Ambriz SL; Herrera GA; Becerril-Luján B; Ochoa-Leyva A; Melendez-Zajgla J; Serpell L; Del Pozo-Yauner L
    Sci Rep; 2019 Feb; 9(1):3123. PubMed ID: 30816248
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation.
    Kazman P; Vielberg MT; Pulido Cendales MD; Hunziger L; Weber B; Hegenbart U; Zacharias M; Köhler R; Schönland S; Groll M; Buchner J
    Elife; 2020 Mar; 9():. PubMed ID: 32151314
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient.
    Swuec P; Lavatelli F; Tasaki M; Paissoni C; Rognoni P; Maritan M; Brambilla F; Milani P; Mauri P; Camilloni C; Palladini G; Merlini G; Ricagno S; Bolognesi M
    Nat Commun; 2019 Mar; 10(1):1269. PubMed ID: 30894521
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Disclosing the Mechanism of Spontaneous Aggregation and Template-Induced Misfolding of the Key Hexapeptide (PHF6) of Tau Protein Based on Molecular Dynamics Simulation.
    Liu H; Zhong H; Liu X; Zhou S; Tan S; Liu H; Yao X
    ACS Chem Neurosci; 2019 Dec; 10(12):4810-4823. PubMed ID: 31661961
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exploring the sequence features determining amyloidosis in human antibody light chains.
    Rawat P; Prabakaran R; Kumar S; Gromiha MM
    Sci Rep; 2021 Jul; 11(1):13785. PubMed ID: 34215782
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Immunoglobulin light chain amyloid aggregation.
    Blancas-Mejia LM; Misra P; Dick CJ; Cooper SA; Redhage KR; Bergman MR; Jordan TL; Maar K; Ramirez-Alvarado M
    Chem Commun (Camb); 2018 Sep; 54(76):10664-10674. PubMed ID: 30087961
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular mechanism of amyloidogenic mutations in hypervariable regions of antibody light chains.
    Rottenaicher GJ; Weber B; Rührnößl F; Kazman P; Absmeier RM; Hitzenberger M; Zacharias M; Buchner J
    J Biol Chem; 2021; 296():100334. PubMed ID: 33508322
    [TBL] [Abstract][Full Text] [Related]  

  • 9. In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study.
    Ami D; Lavatelli F; Rognoni P; Palladini G; Raimondi S; Giorgetti S; Monti L; Doglia SM; Natalello A; Merlini G
    Sci Rep; 2016 Jul; 6():29096. PubMed ID: 27373200
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanistic insights into the aggregation pathway of the patient-derived immunoglobulin light chain variable domain protein FOR005.
    Pradhan T; Sarkar R; Meighen-Berger KM; Feige MJ; Zacharias M; Reif B
    Nat Commun; 2023 Jun; 14(1):3755. PubMed ID: 37353525
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heat-induced native dimerization prevents amyloid formation by variable domain from immunoglobulin light-chain REI.
    Nawata M; Tsutsumi H; Kobayashi Y; Unzai S; Mine S; Nakamura T; Uegaki K; Kamikubo H; Kataoka M; Hamada D
    FEBS J; 2017 Sep; 284(18):3114-3127. PubMed ID: 28736891
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanistic Insights into the Early Events in the Aggregation of Immunoglobulin Light Chains.
    Misra P; Blancas-Mejia LM; Ramirez-Alvarado M
    Biochemistry; 2019 Jul; 58(29):3155-3168. PubMed ID: 31287666
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis.
    Brumshtein B; Esswein SR; Sawaya MR; Rosenberg G; Ly AT; Landau M; Eisenberg DS
    J Biol Chem; 2018 Dec; 293(51):19659-19671. PubMed ID: 30355736
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
    Oberti L; Rognoni P; Barbiroli A; Lavatelli F; Russo R; Maritan M; Palladini G; Bolognesi M; Merlini G; Ricagno S
    Sci Rep; 2017 Dec; 7(1):16809. PubMed ID: 29196671
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis.
    Radamaker L; Lin YH; Annamalai K; Huhn S; Hegenbart U; Schönland SO; Fritz G; Schmidt M; Fändrich M
    Nat Commun; 2019 Mar; 10(1):1103. PubMed ID: 30894526
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cu(II) binding to the λ6aJL2-R24G antibody light chain protein associated with light chain amyloidosis disease: The role of histidines.
    Pelaez-Aguilar AE; Mata-Salgado F; Morales-Ortiz A; Millán-Pacheco C; Olvera-Carranza C; Salgado-Delgado J; Pastor N; Rivillas-Acevedo L
    Int J Biol Macromol; 2024 Jun; 270(Pt 2):132393. PubMed ID: 38761898
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effect of amino acid mutations on the conformational dynamics of amyloidogenic immunoglobulin light-chains: A combined NMR and in silico study.
    Mukherjee S; Pondaven SP; Hand K; Madine J; Jaroniec CP
    Sci Rep; 2017 Sep; 7(1):10339. PubMed ID: 28871194
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Why is Dimeric 3D Domain Swapping in Antibody Light Chains Missing from the Solution? Atomistic Insights Mechanisms.
    Duan L; Hengphasatporn K; Sakai T; Fujiki R; Yoshida N; Hirota S; Shigeta Y
    J Phys Chem B; 2024 Sep; 128(38):9086-9093. PubMed ID: 39268801
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Truncation of the constant domain drives amyloid formation by immunoglobulin light chains.
    Lavatelli F; Natalello A; Marchese L; Ami D; Corazza A; Raimondi S; Mimmi MC; Malinverni S; Mangione PP; Palmer MT; Lampis A; Concardi M; Verona G; Canetti D; Arbustini E; Bellotti V; Giorgetti S
    J Biol Chem; 2024 Apr; 300(4):107174. PubMed ID: 38499153
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Driving forces in amyloidosis: How does a light chain make a heavy heart?
    Otzen DE
    J Biol Chem; 2021; 296():100785. PubMed ID: 34019874
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.