133 related articles for article (PubMed ID: 38314653)
1. Computational evidences of a misfolding event in an aggregation-prone light chain preceding the formation of the non-native pathogenic dimer.
Desantis F; Miotto M; Milanetti E; Ruocco G; Di Rienzo L
Proteins; 2024 Jul; 92(7):797-807. PubMed ID: 38314653
[TBL] [Abstract][Full Text] [Related]
2. The CDR1 and Other Regions of Immunoglobulin Light Chains are Hot Spots for Amyloid Aggregation.
Ruiz-Zamora RA; Guillaumé S; Al-Hilaly YK; Al-Garawi Z; Rodríguez-Alvarez FJ; Zavala-Padilla G; Pérez-Carreón JI; Rodríguez-Ambriz SL; Herrera GA; Becerril-Luján B; Ochoa-Leyva A; Melendez-Zajgla J; Serpell L; Del Pozo-Yauner L
Sci Rep; 2019 Feb; 9(1):3123. PubMed ID: 30816248
[TBL] [Abstract][Full Text] [Related]
3. Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation.
Kazman P; Vielberg MT; Pulido Cendales MD; Hunziger L; Weber B; Hegenbart U; Zacharias M; Köhler R; Schönland S; Groll M; Buchner J
Elife; 2020 Mar; 9():. PubMed ID: 32151314
[TBL] [Abstract][Full Text] [Related]
4. Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient.
Swuec P; Lavatelli F; Tasaki M; Paissoni C; Rognoni P; Maritan M; Brambilla F; Milani P; Mauri P; Camilloni C; Palladini G; Merlini G; Ricagno S; Bolognesi M
Nat Commun; 2019 Mar; 10(1):1269. PubMed ID: 30894521
[TBL] [Abstract][Full Text] [Related]
5. Disclosing the Mechanism of Spontaneous Aggregation and Template-Induced Misfolding of the Key Hexapeptide (PHF6) of Tau Protein Based on Molecular Dynamics Simulation.
Liu H; Zhong H; Liu X; Zhou S; Tan S; Liu H; Yao X
ACS Chem Neurosci; 2019 Dec; 10(12):4810-4823. PubMed ID: 31661961
[TBL] [Abstract][Full Text] [Related]
6. Exploring the sequence features determining amyloidosis in human antibody light chains.
Rawat P; Prabakaran R; Kumar S; Gromiha MM
Sci Rep; 2021 Jul; 11(1):13785. PubMed ID: 34215782
[TBL] [Abstract][Full Text] [Related]
7. Immunoglobulin light chain amyloid aggregation.
Blancas-Mejia LM; Misra P; Dick CJ; Cooper SA; Redhage KR; Bergman MR; Jordan TL; Maar K; Ramirez-Alvarado M
Chem Commun (Camb); 2018 Sep; 54(76):10664-10674. PubMed ID: 30087961
[TBL] [Abstract][Full Text] [Related]
8. Molecular mechanism of amyloidogenic mutations in hypervariable regions of antibody light chains.
Rottenaicher GJ; Weber B; Rührnößl F; Kazman P; Absmeier RM; Hitzenberger M; Zacharias M; Buchner J
J Biol Chem; 2021; 296():100334. PubMed ID: 33508322
[TBL] [Abstract][Full Text] [Related]
9. In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study.
Ami D; Lavatelli F; Rognoni P; Palladini G; Raimondi S; Giorgetti S; Monti L; Doglia SM; Natalello A; Merlini G
Sci Rep; 2016 Jul; 6():29096. PubMed ID: 27373200
[TBL] [Abstract][Full Text] [Related]
10. Mechanistic insights into the aggregation pathway of the patient-derived immunoglobulin light chain variable domain protein FOR005.
Pradhan T; Sarkar R; Meighen-Berger KM; Feige MJ; Zacharias M; Reif B
Nat Commun; 2023 Jun; 14(1):3755. PubMed ID: 37353525
[TBL] [Abstract][Full Text] [Related]
11. Heat-induced native dimerization prevents amyloid formation by variable domain from immunoglobulin light-chain REI.
Nawata M; Tsutsumi H; Kobayashi Y; Unzai S; Mine S; Nakamura T; Uegaki K; Kamikubo H; Kataoka M; Hamada D
FEBS J; 2017 Sep; 284(18):3114-3127. PubMed ID: 28736891
[TBL] [Abstract][Full Text] [Related]
12. Mechanistic Insights into the Early Events in the Aggregation of Immunoglobulin Light Chains.
Misra P; Blancas-Mejia LM; Ramirez-Alvarado M
Biochemistry; 2019 Jul; 58(29):3155-3168. PubMed ID: 31287666
[TBL] [Abstract][Full Text] [Related]
13. Identification of two principal amyloid-driving segments in variable domains of Ig light chains in systemic light-chain amyloidosis.
Brumshtein B; Esswein SR; Sawaya MR; Rosenberg G; Ly AT; Landau M; Eisenberg DS
J Biol Chem; 2018 Dec; 293(51):19659-19671. PubMed ID: 30355736
[TBL] [Abstract][Full Text] [Related]
14. Cu(II) binding to the λ6aJL2-R24G antibody light chain protein associated with light chain amyloidosis disease: The role of histidines.
Pelaez-Aguilar AE; Mata-Salgado F; Morales-Ortiz A; Millán-Pacheco C; Olvera-Carranza C; Salgado-Delgado J; Pastor N; Rivillas-Acevedo L
Int J Biol Macromol; 2024 Jun; 270(Pt 2):132393. PubMed ID: 38761898
[TBL] [Abstract][Full Text] [Related]
15. Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity.
Oberti L; Rognoni P; Barbiroli A; Lavatelli F; Russo R; Maritan M; Palladini G; Bolognesi M; Merlini G; Ricagno S
Sci Rep; 2017 Dec; 7(1):16809. PubMed ID: 29196671
[TBL] [Abstract][Full Text] [Related]
16. Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis.
Radamaker L; Lin YH; Annamalai K; Huhn S; Hegenbart U; Schönland SO; Fritz G; Schmidt M; Fändrich M
Nat Commun; 2019 Mar; 10(1):1103. PubMed ID: 30894526
[TBL] [Abstract][Full Text] [Related]
17. Effect of amino acid mutations on the conformational dynamics of amyloidogenic immunoglobulin light-chains: A combined NMR and in silico study.
Mukherjee S; Pondaven SP; Hand K; Madine J; Jaroniec CP
Sci Rep; 2017 Sep; 7(1):10339. PubMed ID: 28871194
[TBL] [Abstract][Full Text] [Related]
18. Truncation of the constant domain drives amyloid formation by immunoglobulin light chains.
Lavatelli F; Natalello A; Marchese L; Ami D; Corazza A; Raimondi S; Mimmi MC; Malinverni S; Mangione PP; Palmer MT; Lampis A; Concardi M; Verona G; Canetti D; Arbustini E; Bellotti V; Giorgetti S
J Biol Chem; 2024 Apr; 300(4):107174. PubMed ID: 38499153
[TBL] [Abstract][Full Text] [Related]
19. Driving forces in amyloidosis: How does a light chain make a heavy heart?
Otzen DE
J Biol Chem; 2021; 296():100785. PubMed ID: 34019874
[TBL] [Abstract][Full Text] [Related]
20. Seeded fibrils of the germline variant of human λ-III immunoglobulin light chain FOR005 have a similar core as patient fibrils with reduced stability.
Pradhan T; Annamalai K; Sarkar R; Huhn S; Hegenbart U; Schönland S; Fändrich M; Reif B
J Biol Chem; 2020 Dec; 295(52):18474-18484. PubMed ID: 33093170
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
