BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 38319712)

  • 1. Differential histone acetylation and super-enhancer regulation underlie melanoma cell dedifferentiation.
    Mendelson K; Martin TC; Nguyen CB; Hsu M; Xu J; Lang C; Dummer R; Saenger Y; Messina JL; Sondak VK; Desman G; Hasson D; Bernstein E; Parsons RE; Celebi JT
    JCI Insight; 2024 Feb; 9(6):. PubMed ID: 38319712
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MEK inhibition remodels the active chromatin landscape and induces SOX10 genomic recruitment in BRAF(V600E) mutant melanoma cells.
    Fufa TD; Baxter LL; Wedel JC; Gildea DE; ; Loftus SK; Pavan WJ
    Epigenetics Chromatin; 2019 Aug; 12(1):50. PubMed ID: 31399133
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combined treatment with CBP and BET inhibitors reverses inadvertent activation of detrimental super enhancer programs in DIPG cells.
    Wiese M; Hamdan FH; Kubiak K; Diederichs C; Gielen GH; Nussbaumer G; Carcaboso AM; Hulleman E; Johnsen SA; Kramm CM
    Cell Death Dis; 2020 Aug; 11(8):673. PubMed ID: 32826850
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state.
    Verfaillie A; Imrichova H; Atak ZK; Dewaele M; Rambow F; Hulselmans G; Christiaens V; Svetlichnyy D; Luciani F; Van den Mooter L; Claerhout S; Fiers M; Journe F; Ghanem GE; Herrmann C; Halder G; Marine JC; Aerts S
    Nat Commun; 2015 Apr; 6():6683. PubMed ID: 25865119
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Plasticity of melanoma cells induced by neural cell crest conditions and three-dimensional growth.
    Ghislin S; Deshayes F; Lauriol J; Middendorp S; Martins I; Al-Daccak R; Alcaide-Loridan C
    Melanoma Res; 2012 Jun; 22(3):184-94. PubMed ID: 22454190
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting Lineage-specific MITF Pathway in Human Melanoma Cell Lines by A-485, the Selective Small-molecule Inhibitor of p300/CBP.
    Wang R; He Y; Robinson V; Yang Z; Hessler P; Lasko LM; Lu X; Bhathena A; Lai A; Uziel T; Lam LT
    Mol Cancer Ther; 2018 Dec; 17(12):2543-2550. PubMed ID: 30266801
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia.
    Ott CJ; Federation AJ; Schwartz LS; Kasar S; Klitgaard JL; Lenci R; Li Q; Lawlor M; Fernandes SM; Souza A; Polaski D; Gadi D; Freedman ML; Brown JR; Bradner JE
    Cancer Cell; 2018 Dec; 34(6):982-995.e7. PubMed ID: 30503705
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1.
    Tomazou EM; Sheffield NC; Schmidl C; Schuster M; Schönegger A; Datlinger P; Kubicek S; Bock C; Kovar H
    Cell Rep; 2015 Feb; 10(7):1082-95. PubMed ID: 25704812
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Oncogenic super-enhancers in cancer: mechanisms and therapeutic targets.
    Bacabac M; Xu W
    Cancer Metastasis Rev; 2023 Jun; 42(2):471-480. PubMed ID: 37059907
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer.
    Sheng T; Ho SWT; Ooi WF; Xu C; Xing M; Padmanabhan N; Huang KK; Ma L; Ray M; Guo YA; Sim NL; Anene-Nzelu CG; Chang MM; Razavi-Mohseni M; Beer MA; Foo RSY; Sundar R; Chan YH; Tan ALK; Ong X; Skanderup AJ; White KP; Jha S; Tan P
    Genome Med; 2021 Oct; 13(1):158. PubMed ID: 34635154
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers.
    Di Giorgio E; Paluvai H; Dalla E; Ranzino L; Renzini A; Moresi V; Minisini M; Picco R; Brancolini C
    Genome Biol; 2021 May; 22(1):129. PubMed ID: 33966634
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Directed Dedifferentiation Using Partial Reprogramming Induces Invasive Phenotype in Melanoma Cells.
    Knappe N; Novak D; Weina K; Bernhardt M; Reith M; Larribere L; Hölzel M; Tüting T; Gebhardt C; Umansky V; Utikal J
    Stem Cells; 2016 Apr; 34(4):832-46. PubMed ID: 26753613
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DBC1 is a key positive regulator of enhancer epigenomic writers KMT2D and p300.
    Kim HJ; Moon SJ; Hong S; Won HH; Kim JH
    Nucleic Acids Res; 2022 Aug; 50(14):7873-7888. PubMed ID: 35801925
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NFATc2 is an intrinsic regulator of melanoma dedifferentiation.
    Perotti V; Baldassari P; Molla A; Vegetti C; Bersani I; Maurichi A; Santinami M; Anichini A; Mortarini R
    Oncogene; 2016 Jun; 35(22):2862-72. PubMed ID: 26387540
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transcriptional Activation of Ecdysone-Responsive Genes Requires H3K27 Acetylation at Enhancers.
    Cheng D; Dong Z; Lin P; Shen G; Xia Q
    Int J Mol Sci; 2022 Sep; 23(18):. PubMed ID: 36142704
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4.
    Diener J; Baggiolini A; Pernebrink M; Dalcher D; Lerra L; Cheng PF; Varum S; Häusel J; Stierli S; Treier M; Studer L; Basler K; Levesque MP; Dummer R; Santoro R; Cantù C; Sommer L
    Nat Commun; 2021 Aug; 12(1):5056. PubMed ID: 34417458
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HDAC7 regulates histone 3 lysine 27 acetylation and transcriptional activity at super-enhancer-associated genes in breast cancer stem cells.
    Caslini C; Hong S; Ban YJ; Chen XS; Ince TA
    Oncogene; 2019 Sep; 38(39):6599-6614. PubMed ID: 31375747
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The CaMV 35S enhancer has a function to change the histone modification state at insertion loci in Arabidopsis thaliana.
    Chen X; Huang H; Xu L
    J Plant Res; 2013 Nov; 126(6):841-6. PubMed ID: 23880941
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Innate immune receptor signaling induces transient melanoma dedifferentiation while preserving immunogenicity.
    Thier B; Zhao F; Stupia S; Brüggemann A; Koch J; Schulze N; Horn S; Coch C; Hartmann G; Sucker A; Schadendorf D; Paschen A
    J Immunother Cancer; 2022 Jun; 10(6):. PubMed ID: 35697379
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone H4 asymmetrically dimethylated at arginine 3 (H4R3me2a), a mark of super-enhancers.
    Sudhakar SRN; Wu L; Patel S; Zovoilis A; Davie JR
    Biochem Cell Biol; 2024 Apr; 102(2):145-158. PubMed ID: 38011682
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.