147 related articles for article (PubMed ID: 38325369)
1. Fluorinated cGAMP analogs, which act as STING agonists and are not cleavable by poxins: Structural basis of their function.
Klima M; Dejmek M; Duchoslav V; Eisenreichova A; Sala M; Chalupsky K; Chalupska D; Novotná B; Birkuš G; Nencka R; Boura E
Structure; 2024 Apr; 32(4):433-439.e4. PubMed ID: 38325369
[TBL] [Abstract][Full Text] [Related]
2. Viral and metazoan poxins are cGAMP-specific nucleases that restrict cGAS-STING signalling.
Eaglesham JB; Pan Y; Kupper TS; Kranzusch PJ
Nature; 2019 Feb; 566(7743):259-263. PubMed ID: 30728498
[TBL] [Abstract][Full Text] [Related]
3. Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict.
Eaglesham JB; McCarty KL; Kranzusch PJ
Elife; 2020 Nov; 9():. PubMed ID: 33191912
[TBL] [Abstract][Full Text] [Related]
4. Novel Poxin Stable cGAMP-Derivatives Are Remarkable STING Agonists.
Stazzoni S; Böhmer DFR; Hernichel F; Özdemir D; Pappa A; Drexler D; Bauernfried S; Witte G; Wagner M; Veth S; Hopfner KP; Hornung V; König LM; Carell T
Angew Chem Int Ed Engl; 2022 Oct; 61(40):e202207175. PubMed ID: 35876840
[TBL] [Abstract][Full Text] [Related]
5. The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.
Hall J; Ralph EC; Shanker S; Wang H; Byrnes LJ; Horst R; Wong J; Brault A; Dumlao D; Smith JF; Dakin LA; Schmitt DC; Trujillo J; Vincent F; Griffor M; Aulabaugh AE
Protein Sci; 2017 Dec; 26(12):2367-2380. PubMed ID: 28940468
[TBL] [Abstract][Full Text] [Related]
6. 2',3'-Cyclic GMP-AMP Dinucleotides for STING-Mediated Immune Modulation: Principles, Immunotherapeutic Potential, and Synthesis.
Shang M; Lu K; Guan W; Cao S; Ren M; Zhou C
ChemMedChem; 2022 Jan; 17(2):e202100671. PubMed ID: 34807508
[TBL] [Abstract][Full Text] [Related]
7. Design, Synthesis and Biological Evaluation of (2',5' and 3'5'-Linked) cGAMP Analogs that Activate Stimulator of Interferon Genes (STING).
Xie X; Liu J; Wang X
Molecules; 2020 Nov; 25(22):. PubMed ID: 33198423
[TBL] [Abstract][Full Text] [Related]
8. cGAMP-activated cGAS-STING signaling: its bacterial origins and evolutionary adaptation by metazoans.
Patel DJ; Yu Y; Xie W
Nat Struct Mol Biol; 2023 Mar; 30(3):245-260. PubMed ID: 36894694
[TBL] [Abstract][Full Text] [Related]
9. Assessing the cGAS-cGAMP-STING Activity of Cancer Cells.
Pépin G; Gantier MP
Methods Mol Biol; 2018; 1725():257-266. PubMed ID: 29322423
[TBL] [Abstract][Full Text] [Related]
10. SMPDL3A is a cGAMP-degrading enzyme induced by LXR-mediated lipid metabolism to restrict cGAS-STING DNA sensing.
Hou Y; Wang Z; Liu P; Wei X; Zhang Z; Fan S; Zhang L; Han F; Song Y; Chu L; Zhang C
Immunity; 2023 Nov; 56(11):2492-2507.e10. PubMed ID: 37890481
[TBL] [Abstract][Full Text] [Related]
11. The Chemistry of the Noncanonical Cyclic Dinucleotide 2'3'-cGAMP and Its Analogs.
Schwede F; Genieser HG; Rentsch A
Handb Exp Pharmacol; 2017; 238():359-384. PubMed ID: 27392950
[TBL] [Abstract][Full Text] [Related]
12. Virology: Poxins Soothe the STING.
Decout A; Ablasser A
Curr Biol; 2019 May; 29(9):R332-R334. PubMed ID: 31063727
[TBL] [Abstract][Full Text] [Related]
13. cGAS facilitates sensing of extracellular cyclic dinucleotides to activate innate immunity.
Liu H; Moura-Alves P; Pei G; Mollenkopf HJ; Hurwitz R; Wu X; Wang F; Liu S; Ma M; Fei Y; Zhu C; Koehler AB; Oberbeck-Mueller D; Hahnke K; Klemm M; Guhlich-Bornhof U; Ge B; Tuukkanen A; Kolbe M; Dorhoi A; Kaufmann SH
EMBO Rep; 2019 Apr; 20(4):. PubMed ID: 30872316
[TBL] [Abstract][Full Text] [Related]
14. Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA.
Kato K; Omura H; Ishitani R; Nureki O
Annu Rev Biochem; 2017 Jun; 86():541-566. PubMed ID: 28399655
[TBL] [Abstract][Full Text] [Related]
15. The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING.
Diner EJ; Burdette DL; Wilson SC; Monroe KM; Kellenberger CA; Hyodo M; Hayakawa Y; Hammond MC; Vance RE
Cell Rep; 2013 May; 3(5):1355-61. PubMed ID: 23707065
[TBL] [Abstract][Full Text] [Related]
16. Novel DCPIB analogs as dual inhibitors of VRAC/TREK1 channels reduced cGAS-STING mediated interferon responses.
Zhi Y; Liu J; Kuang P; Zhang X; Xu Z; Chen Y; Lin X; Wu X; Zhou P; Chen J
Biochem Pharmacol; 2022 May; 199():114988. PubMed ID: 35278418
[TBL] [Abstract][Full Text] [Related]
17. Design, Synthesis, and Biochemical and Biological Evaluation of Novel 7-Deazapurine Cyclic Dinucleotide Analogues as STING Receptor Agonists.
Vavřina Z; Perlíková P; Milisavljević N; Chevrier F; Smola M; Smith J; Dejmek M; Havlíček V; Buděšínský M; Liboska R; Vaneková L; Brynda J; Boura E; Řezáčová P; Hocek M; Birkuš G
J Med Chem; 2022 Oct; 65(20):14082-14103. PubMed ID: 36201304
[TBL] [Abstract][Full Text] [Related]
18. Crystal structures of porcine STING
Cong X; Yuan Z; Du Y; Wu B; Lu D; Wu X; Zhang Y; Li F; Wei B; Li J; Wu J; Xu S; Wang J; Qi J; Shang G; Gu L
J Biol Chem; 2019 Jul; 294(30):11420-11432. PubMed ID: 31167783
[TBL] [Abstract][Full Text] [Related]
19. Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy.
Dejmek M; Brazdova A; Otava T; Polidarova MP; Klíma M; Smola M; Vavrina Z; Buděšínský M; Dračínský M; Liboska R; Boura E; Birkuš G; Nencka R
Eur J Med Chem; 2023 Nov; 259():115685. PubMed ID: 37567057
[TBL] [Abstract][Full Text] [Related]
20. Structural Flexibility and Conformation Features of Cyclic Dinucleotides in Aqueous Solutions.
Che X; Zhang J; Zhu Y; Yang L; Quan H; Gao YQ
J Phys Chem B; 2016 Mar; 120(10):2670-80. PubMed ID: 26878265
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]