BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 38326620)

  • 1. Allosteric modulation and G-protein selectivity of the Ca
    He F; Wu CG; Gao Y; Rahman SN; Zaoralová M; Papasergi-Scott MM; Gu TJ; Robertson MJ; Seven AB; Li L; Mathiesen JM; Skiniotis G
    Nature; 2024 Feb; 626(8001):1141-1148. PubMed ID: 38326620
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Asymmetric activation of the calcium-sensing receptor homodimer.
    Gao Y; Robertson MJ; Rahman SN; Seven AB; Zhang C; Meyerowitz JG; Panova O; Hannan FM; Thakker RV; Bräuner-Osborne H; Mathiesen JM; Skiniotis G
    Nature; 2021 Jul; 595(7867):455-459. PubMed ID: 34194040
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Calcium-Sensing Receptor Internalization Is
    Mos I; Jacobsen SE; Foster SR; Bräuner-Osborne H
    Mol Pharmacol; 2019 Oct; 96(4):463-474. PubMed ID: 31399503
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca
    Ling S; Shi P; Liu S; Meng X; Zhou Y; Sun W; Chang S; Zhang X; Zhang L; Shi C; Sun D; Liu L; Tian C
    Cell Res; 2021 Apr; 31(4):383-394. PubMed ID: 33603117
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders.
    Babinsky VN; Hannan FM; Gorvin CM; Howles SA; Nesbit MA; Rust N; Hanyaloglu AC; Hu J; Spiegel AM; Thakker RV
    J Biol Chem; 2016 May; 291(20):10876-85. PubMed ID: 26994139
    [TBL] [Abstract][Full Text] [Related]  

  • 6. International Union of Basic and Clinical Pharmacology. CVIII. Calcium-Sensing Receptor Nomenclature, Pharmacology, and Function.
    Leach K; Hannan FM; Josephs TM; Keller AN; Møller TC; Ward DT; Kallay E; Mason RS; Thakker RV; Riccardi D; Conigrave AD; Bräuner-Osborne H
    Pharmacol Rev; 2020 Jul; 72(3):558-604. PubMed ID: 32467152
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biased signaling of Ca
    Kienitz MC; Niemeyer A; König GM; Kostenis E; Pott L; Rinne A
    J Mol Cell Cardiol; 2019 May; 130():107-121. PubMed ID: 30935998
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural insights into the activation of human calcium-sensing receptor.
    Chen X; Wang L; Cui Q; Ding Z; Han L; Kou Y; Zhang W; Wang H; Jia X; Dai M; Shi Z; Li Y; Li X; Geng Y
    Elife; 2021 Sep; 10():. PubMed ID: 34467854
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of Global and Ligand-Specific Calcium Sensing Receptor Activation Mechanisms.
    Keller AN; Kufareva I; Josephs TM; Diao J; Mai VT; Conigrave AD; Christopoulos A; Gregory KJ; Leach K
    Mol Pharmacol; 2018 Jun; 93(6):619-630. PubMed ID: 29636377
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Calcium-sensing receptor-mediated activation of phospholipase C-gamma1 is downstream of phospholipase C-beta and protein kinase C in MC3T3-E1 osteoblasts.
    Godwin SL; Soltoff SP
    Bone; 2002 Apr; 30(4):559-66. PubMed ID: 11934646
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural mechanism of ligand activation in human calcium-sensing receptor.
    Geng Y; Mosyak L; Kurinov I; Zuo H; Sturchler E; Cheng TC; Subramanyam P; Brown AP; Brennan SC; Mun HC; Bush M; Chen Y; Nguyen TX; Cao B; Chang DD; Quick M; Conigrave AD; Colecraft HM; McDonald P; Fan QR
    Elife; 2016 Jul; 5():. PubMed ID: 27434672
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cinacalcet corrects biased allosteric modulation of CaSR by AHH autoantibody.
    Makita N; Ando T; Sato J; Manaka K; Mitani K; Kikuchi Y; Niwa T; Ootaki M; Takeba Y; Matsumoto N; Kawakami A; Ogawa T; Nangaku M; Iiri T
    JCI Insight; 2019 Apr; 4(8):. PubMed ID: 30996138
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Pharmacological characteristics of drugs targeted on calcium-sensing receptor.-properties of cinacalcet hydrochloride as allosteric modulator].
    Nagano N; Tsutsui T
    Clin Calcium; 2016 Jun; 26(6):839-50. PubMed ID: 27230839
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Calcium-sensing receptor (CaSR): pharmacological properties and signaling pathways.
    Conigrave AD; Ward DT
    Best Pract Res Clin Endocrinol Metab; 2013 Jun; 27(3):315-31. PubMed ID: 23856262
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs.
    Zhang M; Gui M; Wang ZF; Gorgulla C; Yu JJ; Wu H; Sun ZJ; Klenk C; Merklinger L; Morstein L; Hagn F; Plückthun A; Brown A; Nasr ML; Wagner G
    Nat Struct Mol Biol; 2021 Mar; 28(3):258-267. PubMed ID: 33633398
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Recent updates on the calcium-sensing receptor as a drug target.
    Trivedi R; Mithal A; Chattopadhyay N
    Curr Med Chem; 2008; 15(2):178-86. PubMed ID: 18220773
    [TBL] [Abstract][Full Text] [Related]  

  • 17. An acquired hypocalciuric hypercalcemia autoantibody induces allosteric transition among active human Ca-sensing receptor conformations.
    Makita N; Sato J; Manaka K; Shoji Y; Oishi A; Hashimoto M; Fujita T; Iiri T
    Proc Natl Acad Sci U S A; 2007 Mar; 104(13):5443-8. PubMed ID: 17372216
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Impact of clinically relevant mutations on the pharmacoregulation and signaling bias of the calcium-sensing receptor by positive and negative allosteric modulators.
    Leach K; Wen A; Cook AE; Sexton PM; Conigrave AD; Christopoulos A
    Endocrinology; 2013 Mar; 154(3):1105-16. PubMed ID: 23372019
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi-functional Bias.
    Bolognini D; Moss CE; Nilsson K; Petersson AU; Donnelly I; Sergeev E; König GM; Kostenis E; Kurowska-Stolarska M; Miller A; Dekker N; Tobin AB; Milligan G
    J Biol Chem; 2016 Sep; 291(36):18915-31. PubMed ID: 27385588
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biased agonism of the calcium-sensing receptor.
    Thomsen AR; Hvidtfeldt M; Bräuner-Osborne H
    Cell Calcium; 2012 Feb; 51(2):107-16. PubMed ID: 22192592
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.