BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 38328115)

  • 1. Myotubularin-related proteins regulate KRAS function by controlling plasma membrane levels of polyphosphoinositides and phosphatidylserine.
    Henkels KM; Miller TE; Naji A; van der Hoeven R; Liang H; Zhou Y; Hammond GRV; Hancock JF; Cho KJ
    bioRxiv; 2024 Jan; ():. PubMed ID: 38328115
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Components of the phosphatidylserine endoplasmic reticulum to plasma membrane transport mechanism as targets for KRAS inhibition in pancreatic cancer.
    Kattan WE; Liu J; Montufar-Solis D; Liang H; Brahmendra Barathi B; van der Hoeven R; Zhou Y; Hancock JF
    Proc Natl Acad Sci U S A; 2021 Dec; 118(51):. PubMed ID: 34903667
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting plasma membrane phosphatidylserine content to inhibit oncogenic KRAS function.
    Kattan WE; Chen W; Ma X; Lan TH; van der Hoeven D; van der Hoeven R; Hancock JF
    Life Sci Alliance; 2019 Oct; 2(5):. PubMed ID: 31451509
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The involvement of oxysterol-binding protein related protein (ORP) 6 in the counter-transport of phosphatidylinositol-4-phosphate (PI4P) and phosphatidylserine (PS) in neurons.
    Mochizuki S; Miki H; Zhou R; Noda Y
    Biochem Biophys Rep; 2022 Jul; 30():101257. PubMed ID: 35518199
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The KRAS and other prenylated polybasic domain membrane anchors recognize phosphatidylserine acyl chain structure.
    Zhou Y; Prakash PS; Liang H; Gorfe AA; Hancock JF
    Proc Natl Acad Sci U S A; 2021 Feb; 118(6):. PubMed ID: 33526670
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acylpeptide hydrolase is a novel regulator of KRAS plasma membrane localization and function.
    Tan L; Cho KJ; Kattan WE; Garrido CM; Zhou Y; Neupane P; Capon RJ; Hancock JF
    J Cell Sci; 2019 Jul; 132(15):. PubMed ID: 31266814
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Depletion of phosphatidylinositol 4-phosphate at the Golgi translocates K-Ras to mitochondria.
    Miller TE; Henkels KM; Huddleston M; Salisbury R; Hussain SM; Sasaki AT; Cho KJ
    J Cell Sci; 2019 Aug; 132(16):. PubMed ID: 31331963
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions.
    Sohn M; Ivanova P; Brown HA; Toth DJ; Varnai P; Kim YJ; Balla T
    Proc Natl Acad Sci U S A; 2016 Apr; 113(16):4314-9. PubMed ID: 27044099
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PtdSer as a signaling lipid determined by privileged localization of ORP5 and ORP8 at ER/PM junctional foci to determine PM and ER PtdSer/PI(4)P ratio and cell function.
    Chung WY; Ahuja M; McNally BA; Leibow SR; Ohman HKE; Movahed Abtahi A; Muallem S
    Proc Natl Acad Sci U S A; 2023 Aug; 120(35):e2301410120. PubMed ID: 37607230
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Osh Proteins Control Nanoscale Lipid Organization Necessary for PI(4,5)P
    Nishimura T; Gecht M; Covino R; Hummer G; Surma MA; Klose C; Arai H; Kono N; Stefan CJ
    Mol Cell; 2019 Sep; 75(5):1043-1057.e8. PubMed ID: 31402097
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oxysterol-binding protein-related protein (ORP) 6 localizes to the ER and ER-plasma membrane contact sites and is involved in the turnover of PI4P in cerebellar granule neurons.
    Mochizuki S; Miki H; Zhou R; Kido Y; Nishimura W; Kikuchi M; Noda Y
    Exp Cell Res; 2018 Sep; 370(2):601-612. PubMed ID: 30028970
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Osh6 Revisited: Control of PS Transport by the Concerted Actions of PI4P and Sac1 Phosphatase.
    Eisenreichova A; Różycki B; Boura E; Humpolickova J
    Front Mol Biosci; 2021; 8():747601. PubMed ID: 34712698
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Monitoring Non-vesicular Transport of Phosphatidylserine and Phosphatidylinositol 4-Phosphate in Intact Cells by BRET Analysis.
    Sohn M; Toth DJ; Balla T
    Methods Mol Biol; 2019; 1949():13-22. PubMed ID: 30790245
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PI(4,5)P
    Sohn M; Korzeniowski M; Zewe JP; Wills RC; Hammond GRV; Humpolickova J; Vrzal L; Chalupska D; Veverka V; Fairn GD; Boura E; Balla T
    J Cell Biol; 2018 May; 217(5):1797-1813. PubMed ID: 29472386
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Membrane binding and subcellular localization of retroviral Gag proteins are differentially regulated by MA interactions with phosphatidylinositol-(4,5)-bisphosphate and RNA.
    Inlora J; Collins DR; Trubin ME; Chung JY; Ono A
    mBio; 2014 Dec; 5(6):e02202. PubMed ID: 25491356
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins.
    Gulyás G; Radvánszki G; Matuska R; Balla A; Hunyady L; Balla T; Várnai P
    J Biol Chem; 2017 Nov; 292(46):18862-18877. PubMed ID: 28939768
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ORP3 phosphorylation regulates phosphatidylinositol 4-phosphate and Ca
    Gulyás G; Sohn M; Kim YJ; Várnai P; Balla T
    J Cell Sci; 2020 Mar; 133(6):. PubMed ID: 32041906
    [TBL] [Abstract][Full Text] [Related]  

  • 18. ORP2 Delivers Cholesterol to the Plasma Membrane in Exchange for Phosphatidylinositol 4, 5-Bisphosphate (PI(4,5)P
    Wang H; Ma Q; Qi Y; Dong J; Du X; Rae J; Wang J; Wu WF; Brown AJ; Parton RG; Wu JW; Yang H
    Mol Cell; 2019 Feb; 73(3):458-473.e7. PubMed ID: 30581148
    [TBL] [Abstract][Full Text] [Related]  

  • 19. INTRACELLULAR TRANSPORT. Phosphatidylserine transport by ORP/Osh proteins is driven by phosphatidylinositol 4-phosphate.
    Moser von Filseck J; Čopič A; Delfosse V; Vanni S; Jackson CL; Bourguet W; Drin G
    Science; 2015 Jul; 349(6246):432-6. PubMed ID: 26206936
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Orthogonal Targeting of SAC1 to Mitochondria Implicates ORP2 as a Major Player in PM PI4P Turnover.
    Doyle CP; Rectenwald A; Timple L; Hammond GRV
    Contact (Thousand Oaks); 2024; 7():25152564241229272. PubMed ID: 38327560
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.