BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 38330869)

  • 1. Tackling Influenza A virus by M2 ion channel blockers: Latest progress and limitations.
    Kumar G; Sakharam KA
    Eur J Med Chem; 2024 Mar; 267():116172. PubMed ID: 38330869
    [TBL] [Abstract][Full Text] [Related]  

  • 2. An M2-V27A channel blocker demonstrates potent in vitro and in vivo antiviral activities against amantadine-sensitive and -resistant influenza A viruses.
    Hu Y; Musharrafieh R; Ma C; Zhang J; Smee DF; DeGrado WF; Wang J
    Antiviral Res; 2017 Apr; 140():45-54. PubMed ID: 28087313
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and pharmacological characterization of inhibitors of amantadine-resistant mutants of the M2 ion channel of influenza A virus.
    Balannik V; Wang J; Ohigashi Y; Jing X; Magavern E; Lamb RA; Degrado WF; Pinto LH
    Biochemistry; 2009 Dec; 48(50):11872-82. PubMed ID: 19905033
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Viral M2 ion channel protein: a promising target for anti-influenza drug discovery.
    Moorthy NS; Poongavanam V; Pratheepa V
    Mini Rev Med Chem; 2014; 14(10):819-30. PubMed ID: 25342196
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Discovery of Potent Antivirals against Amantadine-Resistant Influenza A Viruses by Targeting the M2-S31N Proton Channel.
    Li F; Ma C; Hu Y; Wang Y; Wang J
    ACS Infect Dis; 2016 Oct; 2(10):726-733. PubMed ID: 27657178
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of M2 channel blockers targeting the drug-resistant double mutants M2-S31N/L26I and M2-S31N/V27A from the influenza A viruses.
    Musharrafieh R; Ma C; Wang J
    Eur J Pharm Sci; 2020 Jan; 141():105124. PubMed ID: 31669761
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pharmacological Characterization of the Spectrum of Antiviral Activity and Genetic Barrier to Drug Resistance of M2-S31N Channel Blockers.
    Ma C; Zhang J; Wang J
    Mol Pharmacol; 2016 Sep; 90(3):188-98. PubMed ID: 27385729
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel spirothiazamenthane inhibitors of the influenza A M2 proton channel.
    Arns S; Balgi AD; Shimizu Y; Pfeifer TA; Kumar N; Shidmoossavee FS; Sun S; Tai SS; Agafitei O; Jaquith JB; Bourque E; Niikura M; Roberge M
    Eur J Med Chem; 2016 Sep; 120():64-73. PubMed ID: 27187859
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Influenza a virus M2 ion channel activity is essential for efficient replication in tissue culture.
    Takeda M; Pekosz A; Shuck K; Pinto LH; Lamb RA
    J Virol; 2002 Feb; 76(3):1391-9. PubMed ID: 11773413
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Flipping in the pore: discovery of dual inhibitors that bind in different orientations to the wild-type versus the amantadine-resistant S31N mutant of the influenza A virus M2 proton channel.
    Wu Y; Canturk B; Jo H; Ma C; Gianti E; Klein ML; Pinto LH; Lamb RA; Fiorin G; Wang J; DeGrado WF
    J Am Chem Soc; 2014 Dec; 136(52):17987-95. PubMed ID: 25470189
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The L46P mutant confers a novel allosteric mechanism of resistance toward the influenza A virus M2 S31N proton channel blockers.
    Musharrafieh R; Lagarias PI; Ma C; Tan GS; Kolocouris A; Wang J
    Mol Pharmacol; 2019 Aug; 96(2):148-157. PubMed ID: 31175183
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Study of the Activity of Adamantyl Amines against Mutant Influenza A M2 Channels Identified a Polycyclic Cage Amine Triple Blocker, Explored by Molecular Dynamics Simulations and Solid-State NMR.
    Stampolaki Μ; Hoffmann A; Tekwani K; Georgiou K; Tzitzoglaki C; Ma C; Becker S; Schmerer P; Döring K; Stylianakis I; Turcu AL; Wang J; Vázquez S; Andreas LB; Schmidtke M; Kolocouris A
    ChemMedChem; 2023 Aug; 18(16):e202300182. PubMed ID: 37377066
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant.
    Rey-Carrizo M; Torres E; Ma C; Barniol-Xicota M; Wang J; Wu Y; Naesens L; DeGrado WF; Lamb RA; Pinto LH; Vázquez S
    J Med Chem; 2013 Nov; 56(22):9265-74. PubMed ID: 24237039
    [TBL] [Abstract][Full Text] [Related]  

  • 14. M2 protein-a proton channel of influenza A virus.
    Betakova T
    Curr Pharm Des; 2007; 13(31):3231-5. PubMed ID: 18045172
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Designing inhibitors of M2 proton channel against H1N1 swine influenza virus.
    Du QS; Huang RB; Wang SQ; Chou KC
    PLoS One; 2010 Feb; 5(2):e9388. PubMed ID: 20186344
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus.
    Wang J; Wu Y; Ma C; Fiorin G; Wang J; Pinto LH; Lamb RA; Klein ML; Degrado WF
    Proc Natl Acad Sci U S A; 2013 Jan; 110(4):1315-20. PubMed ID: 23302696
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Virtual screening and molecular growth guide the design of inhibitors for the influenza virus drug-resistant mutant M2-V27A/S31N.
    Deng C; Wang X; Wang T; Liu W; Yuan X; Huang Y; Cao S
    J Biomol Struct Dyn; 2024 Jul; 42(10):5253-5267. PubMed ID: 37424098
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus.
    Rey-Carrizo M; Barniol-Xicota M; Ma C; Frigolé-Vivas M; Torres E; Naesens L; Llabrés S; Juárez-Jiménez J; Luque FJ; DeGrado WF; Lamb RA; Pinto LH; Vázquez S
    J Med Chem; 2014 Jul; 57(13):5738-47. PubMed ID: 24941437
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of novel dual inhibitors of the wild-type and the most prevalent drug-resistant mutant, S31N, of the M2 proton channel from influenza A virus.
    Wang J; Ma C; Wang J; Jo H; Canturk B; Fiorin G; Pinto LH; Lamb RA; Klein ML; DeGrado WF
    J Med Chem; 2013 Apr; 56(7):2804-12. PubMed ID: 23437766
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Flu channel drug resistance: a tale of two sites.
    Pielak RM; Chou JJ
    Protein Cell; 2010 Mar; 1(3):246-58. PubMed ID: 21203971
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.