These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 38340342)

  • 81. Neutral Porphyrin Derivative Exerts Anticancer Activity by Targeting Cellular Topoisomerase I (Top1) and Promotes Apoptotic Cell Death without Stabilizing Top1-DNA Cleavage Complexes.
    Das SK; Ghosh A; Paul Chowdhuri S; Halder N; Rehman I; Sengupta S; Sahoo KC; Rath H; Das BB
    J Med Chem; 2018 Feb; 61(3):804-817. PubMed ID: 29290109
    [TBL] [Abstract][Full Text] [Related]  

  • 82. Phenylpyrazolo[1,5-a]quinazolin-5(4H)-one: a suitable scaffold for the development of noncamptothecin topoisomerase I (Top1) inhibitors.
    Taliani S; Pugliesi I; Barresi E; Salerno S; Marchand C; Agama K; Simorini F; La Motta C; Marini AM; Di Leva FS; Marinelli L; Cosconati S; Novellino E; Pommier Y; Di Santo R; Da Settimo F
    J Med Chem; 2013 Sep; 56(18):7458-62. PubMed ID: 23987476
    [TBL] [Abstract][Full Text] [Related]  

  • 83. Nonclassic functions of human topoisomerase I: genome-wide and pharmacologic analyses.
    Miao ZH; Player A; Shankavaram U; Wang YH; Zimonjic DB; Lorenzi PL; Liao ZY; Liu H; Shimura T; Zhang HL; Meng LH; Zhang YW; Kawasaki ES; Popescu NC; Aladjem MI; Goldstein DJ; Weinstein JN; Pommier Y
    Cancer Res; 2007 Sep; 67(18):8752-61. PubMed ID: 17875716
    [TBL] [Abstract][Full Text] [Related]  

  • 84. Genetic evidence for functional interaction of Smc5/6 complex and Top1 with spatial frequency of replication origins required for maintenance of chromosome stability.
    Rai R; Laloraya S
    Curr Genet; 2017 Aug; 63(4):765-776. PubMed ID: 28204881
    [TBL] [Abstract][Full Text] [Related]  

  • 85. TDP2 promotes repair of topoisomerase I-mediated DNA damage in the absence of TDP1.
    Zeng Z; Sharma A; Ju L; Murai J; Umans L; Vermeire L; Pommier Y; Takeda S; Huylebroeck D; Caldecott KW; El-Khamisy SF
    Nucleic Acids Res; 2012 Sep; 40(17):8371-80. PubMed ID: 22740648
    [TBL] [Abstract][Full Text] [Related]  

  • 86. Correlation between topoisomerase I and tyrosyl-DNA phosphodiesterase 1 activities in non-small cell lung cancer tissue.
    Jakobsen AK; Lauridsen KL; Samuel EB; Proszek J; Knudsen BR; Hager H; Stougaard M
    Exp Mol Pathol; 2015 Aug; 99(1):56-64. PubMed ID: 25987486
    [TBL] [Abstract][Full Text] [Related]  

  • 87. Enhanced CPT sensitivity of yeast cells and selective relaxation of Ga14 motif-containing DNA by novel Gal4-topoisomerase I fusion proteins.
    Alessandri M; Beretta GL; Ferretti E; Mancia A; Khobta A; Capranico G
    J Mol Biol; 2004 Mar; 337(2):295-305. PubMed ID: 15003448
    [TBL] [Abstract][Full Text] [Related]  

  • 88. 7-azaindenoisoquinolines as topoisomerase I inhibitors and potential anticancer agents.
    Kiselev E; DeGuire S; Morrell A; Agama K; Dexheimer TS; Pommier Y; Cushman M
    J Med Chem; 2011 Sep; 54(17):6106-16. PubMed ID: 21823606
    [TBL] [Abstract][Full Text] [Related]  

  • 89. The Interplay between G-quadruplex and Transcription.
    Kim N
    Curr Med Chem; 2019; 26(16):2898-2917. PubMed ID: 29284393
    [TBL] [Abstract][Full Text] [Related]  

  • 90. DNA topoisomerase I domain interactions impact enzyme activity and sensitivity to camptothecin.
    Wright CM; van der Merwe M; DeBrot AH; Bjornsti MA
    J Biol Chem; 2015 May; 290(19):12068-78. PubMed ID: 25795777
    [TBL] [Abstract][Full Text] [Related]  

  • 91. G-quadruplex unwinding helicases and their function
    Sauer M; Paeschke K
    Biochem Soc Trans; 2017 Oct; 45(5):1173-1182. PubMed ID: 28939694
    [TBL] [Abstract][Full Text] [Related]  

  • 92. Topoisomerase 1 Regulates Gene Expression in Neurons through Cleavage Complex-Dependent and -Independent Mechanisms.
    Mabb AM; Simon JM; King IF; Lee HM; An LK; Philpot BD; Zylka MJ
    PLoS One; 2016; 11(5):e0156439. PubMed ID: 27231886
    [TBL] [Abstract][Full Text] [Related]  

  • 93. Genomes and G-quadruplexes: for better or for worse.
    Tarsounas M; Tijsterman M
    J Mol Biol; 2013 Nov; 425(23):4782-9. PubMed ID: 24076189
    [TBL] [Abstract][Full Text] [Related]  

  • 94. Structural insight of DNA topoisomerases I from camptothecin-producing plants revealed by molecular dynamics simulations.
    Sirikantaramas S; Meeprasert A; Rungrotmongkol T; Fuji H; Hoshino T; Sudo H; Yamazaki M; Saito K
    Phytochemistry; 2015 May; 113():50-6. PubMed ID: 25733498
    [TBL] [Abstract][Full Text] [Related]  

  • 95. Dynamic localization of DNA topoisomerase I and its functional relevance during Drosophila development.
    Huang W; Liu Z; Rong YS
    G3 (Bethesda); 2021 Sep; 11(9):. PubMed ID: 34544118
    [TBL] [Abstract][Full Text] [Related]  

  • 96. G-quadruplexes on chromosomal DNA negatively regulates topoisomerase 1 activity.
    Liang HT; Yan JY; Yao HJ; Zhang XN; Xing ZM; Liu L; Chen YQ; Li GR; Huang J; He YD; Zheng KW
    Nucleic Acids Res; 2024 Mar; 52(5):2142-2156. PubMed ID: 38340342
    [TBL] [Abstract][Full Text] [Related]  

  • 97. The Functional Consequences of Eukaryotic Topoisomerase 1 Interaction with G-Quadruplex DNA.
    Berroyer A; Kim N
    Genes (Basel); 2020 Feb; 11(2):. PubMed ID: 32059547
    [TBL] [Abstract][Full Text] [Related]  

  • 98. Topoisomerase 1 inhibits MYC promoter activity by inducing G-quadruplex formation.
    Keller JG; Hymøller KM; Thorsager ME; Hansen NY; Erlandsen JU; Tesauro C; Simonsen AKW; Andersen AB; Vandsø Petersen K; Holm LL; Stougaard M; Andresen BS; Kristensen P; Frøhlich R; Knudsen BR
    Nucleic Acids Res; 2022 Jun; 50(11):6332-6342. PubMed ID: 35687110
    [TBL] [Abstract][Full Text] [Related]  

  • 99. The role of topoisomerase I in suppressing genome instability associated with a highly transcribed guanine-rich sequence is not restricted to preventing RNA:DNA hybrid accumulation.
    Yadav P; Owiti N; Kim N
    Nucleic Acids Res; 2016 Jan; 44(2):718-29. PubMed ID: 26527723
    [TBL] [Abstract][Full Text] [Related]  

  • 100. Transcription-associated topoisomerase 2α (TOP2A) activity is a major effector of cytotoxicity induced by G-quadruplex ligands.
    Bossaert M; Pipier A; Riou JF; Noirot C; Nguyên LT; Serre RF; Bouchez O; Defrancq E; Calsou P; Britton S; Gomez D
    Elife; 2021 Jun; 10():. PubMed ID: 34180392
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.