204 related articles for article (PubMed ID: 38343852)
1. Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence.
Mitra J; Dharmalingam P; Kodavati M; Guerrero EN; Rao KS; Garruto RM; Hegde ML
Res Sq; 2024 Mar; ():. PubMed ID: 38343852
[TBL] [Abstract][Full Text] [Related]
2. Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects.
Mitra J; Guerrero EN; Hegde PM; Liachko NF; Wang H; Vasquez V; Gao J; Pandey A; Taylor JP; Kraemer BC; Wu P; Boldogh I; Garruto RM; Mitra S; Rao KS; Hegde ML
Proc Natl Acad Sci U S A; 2019 Mar; 116(10):4696-4705. PubMed ID: 30770445
[TBL] [Abstract][Full Text] [Related]
3. A Commentary on TDP-43 and DNA Damage Response in Amyotrophic Lateral Sclerosis.
Mitra J; Hegde ML
J Exp Neurosci; 2019; 13():1179069519880166. PubMed ID: 31656396
[TBL] [Abstract][Full Text] [Related]
4. Slow motor neurons resist pathological TDP-43 and mediate motor recovery in the rNLS8 model of amyotrophic lateral sclerosis.
Hur SK; Hunter M; Dominique MA; Farag M; Cotton-Samuel D; Khan T; Trojanowski JQ; Spiller KJ; Lee VM
Acta Neuropathol Commun; 2022 May; 10(1):75. PubMed ID: 35568882
[TBL] [Abstract][Full Text] [Related]
5. Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice.
Igaz LM; Kwong LK; Lee EB; Chen-Plotkin A; Swanson E; Unger T; Malunda J; Xu Y; Winton MJ; Trojanowski JQ; Lee VM
J Clin Invest; 2011 Feb; 121(2):726-38. PubMed ID: 21206091
[TBL] [Abstract][Full Text] [Related]
6. Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43.
Walker AK; Spiller KJ; Ge G; Zheng A; Xu Y; Zhou M; Tripathy K; Kwong LK; Trojanowski JQ; Lee VM
Acta Neuropathol; 2015 Nov; 130(5):643-60. PubMed ID: 26197969
[TBL] [Abstract][Full Text] [Related]
7. Amyotrophic lateral sclerosis-associated TDP-43 mutation Q331K prevents nuclear translocation of XRCC4-DNA ligase 4 complex and is linked to genome damage-mediated neuronal apoptosis.
Guerrero EN; Mitra J; Wang H; Rangaswamy S; Hegde PM; Basu P; Rao KS; Hegde ML
Hum Mol Genet; 2019 Aug; 28(15):2459-2476. PubMed ID: 31067307
[TBL] [Abstract][Full Text] [Related]
8. Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia.
Pasetto L; Grassano M; Pozzi S; Luotti S; Sammali E; Migazzi A; Basso M; Spagnolli G; Biasini E; Micotti E; Cerovic M; Carli M; Forloni G; De Marco G; Manera U; Moglia C; Mora G; Traynor BJ; Chiò A; Calvo A; Bonetto V
Brain; 2021 Dec; 144(12):3710-3726. PubMed ID: 34972208
[TBL] [Abstract][Full Text] [Related]
9. Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration.
Riku Y; Iwasaki Y; Ishigaki S; Akagi A; Hasegawa M; Nishioka K; Li Y; Riku M; Ikeuchi T; Fujioka Y; Miyahara H; Sone J; Hattori N; Yoshida M; Katsuno M; Sobue G
Brain; 2022 Aug; 145(8):2769-2784. PubMed ID: 35274674
[TBL] [Abstract][Full Text] [Related]
10. Early Cognitive/Social Deficits and Late Motor Phenotype in Conditional Wild-Type TDP-43 Transgenic Mice.
Alfieri JA; Silva PR; Igaz LM
Front Aging Neurosci; 2016; 8():310. PubMed ID: 28066234
[TBL] [Abstract][Full Text] [Related]
11. TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy.
Atkinson R; Leung J; Bender J; Kirkcaldie M; Vickers J; King A
Dis Model Mech; 2021 Jan; 14(2):. PubMed ID: 33408125
[TBL] [Abstract][Full Text] [Related]
12. Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis.
Ditsworth D; Maldonado M; McAlonis-Downes M; Sun S; Seelman A; Drenner K; Arnold E; Ling SC; Pizzo D; Ravits J; Cleveland DW; Da Cruz S
Acta Neuropathol; 2017 Jun; 133(6):907-922. PubMed ID: 28357566
[TBL] [Abstract][Full Text] [Related]
13. Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy.
Spiller KJ; Cheung CJ; Restrepo CR; Kwong LK; Stieber AM; Trojanowski JQ; Lee VM
J Neurosci; 2016 Jul; 36(29):7707-17. PubMed ID: 27445147
[TBL] [Abstract][Full Text] [Related]
14. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.
Mitchell JC; Constable R; So E; Vance C; Scotter E; Glover L; Hortobagyi T; Arnold ES; Ling SC; McAlonis M; Da Cruz S; Polymenidou M; Tessarolo L; Cleveland DW; Shaw CE
Acta Neuropathol Commun; 2015 Jun; 3():36. PubMed ID: 26108367
[TBL] [Abstract][Full Text] [Related]
15. Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration.
Dutta K; Patel P; Rahimian R; Phaneuf D; Julien JP
Neurotherapeutics; 2017 Apr; 14(2):447-462. PubMed ID: 27928708
[TBL] [Abstract][Full Text] [Related]
16. A robust TDP-43 knock-in mouse model of ALS.
Huang SL; Wu LS; Lee M; Chang CW; Cheng WC; Fang YS; Chen YR; Cheng PL; Shen CJ
Acta Neuropathol Commun; 2020 Jan; 8(1):3. PubMed ID: 31964415
[TBL] [Abstract][Full Text] [Related]
17. Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations.
Konopka A; Whelan DR; Jamali MS; Perri E; Shahheydari H; Toth RP; Parakh S; Robinson T; Cheong A; Mehta P; Vidal M; Ragagnin AMG; Khizhnyak I; Jagaraj CJ; Galper J; Grima N; Deva A; Shadfar S; Nicholson GA; Yang S; Cutts SM; Horejsi Z; Bell TDM; Walker AK; Blair IP; Atkin JD
Mol Neurodegener; 2020 Sep; 15(1):51. PubMed ID: 32907630
[TBL] [Abstract][Full Text] [Related]
18. Enhancing survival motor neuron expression extends lifespan and attenuates neurodegeneration in mutant TDP-43 mice.
Perera ND; Sheean RK; Crouch PJ; White AR; Horne MK; Turner BJ
Hum Mol Genet; 2016 Sep; 25(18):4080-4093. PubMed ID: 27466204
[TBL] [Abstract][Full Text] [Related]
19. Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy.
Khalil B; Chhangani D; Wren MC; Smith CL; Lee JH; Li X; Puttinger C; Tsai CW; Fortin G; Morderer D; Gao J; Liu F; Lim CK; Chen J; Chou CC; Croft CL; Gleixner AM; Donnelly CJ; Golde TE; Petrucelli L; Oskarsson B; Dickson DW; Zhang K; Shorter J; Yoshimura SH; Barmada SJ; Rincon-Limas DE; Rossoll W
Mol Neurodegener; 2022 Dec; 17(1):80. PubMed ID: 36482422
[TBL] [Abstract][Full Text] [Related]
20. TDP-43-The key to understanding amyotrophic lateral sclerosis.
Xu Z; Yang C
Rare Dis; 2014; 2(1):e944443. PubMed ID: 26942097
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
