BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 38349040)

  • 1. Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts.
    Tatsukawa K; Sakamoto R; Kawasoe Y; Kubota Y; Tsurimoto T; Takahashi TS; Ohashi E
    Nucleic Acids Res; 2024 Apr; 52(6):3146-3163. PubMed ID: 38349040
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dna2 initiates resection at clean DNA double-strand breaks.
    Paudyal SC; Li S; Yan H; Hunter T; You Z
    Nucleic Acids Res; 2017 Nov; 45(20):11766-11781. PubMed ID: 28981724
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Smad7 enhances ATM activity by facilitating the interaction between ATM and Mre11-Rad50-Nbs1 complex in DNA double-strand break repair.
    Park S; Kang JM; Kim SJ; Kim H; Hong S; Lee YJ; Kim SJ
    Cell Mol Life Sci; 2015 Feb; 72(3):583-596. PubMed ID: 25063542
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Mre11-Rad50-Nbs1 complex mediates activation of TopBP1 by ATM.
    Yoo HY; Kumagai A; Shevchenko A; Shevchenko A; Dunphy WG
    Mol Biol Cell; 2009 May; 20(9):2351-60. PubMed ID: 19279141
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Importance of Germline and Somatic Alterations in Human
    Otahalova B; Volkova Z; Soukupova J; Kleiblova P; Janatova M; Vocka M; Macurek L; Kleibl Z
    Int J Mol Sci; 2023 Mar; 24(6):. PubMed ID: 36982687
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts.
    Ramírez-Lugo JS; Yoo HY; Yoon SJ; Dunphy WG
    Cell Cycle; 2011 Feb; 10(3):469-80. PubMed ID: 21263215
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks.
    Limbo O; Porter-Goff ME; Rhind N; Russell P
    Mol Cell Biol; 2011 Feb; 31(3):573-83. PubMed ID: 21098122
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A role for the MRN complex in ATR activation via TOPBP1 recruitment.
    Duursma AM; Driscoll R; Elias JE; Cimprich KA
    Mol Cell; 2013 Apr; 50(1):116-22. PubMed ID: 23582259
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Mre11-Rad50-Nbs1 (MRN) complex has a specific role in the activation of Chk1 in response to stalled replication forks.
    Lee J; Dunphy WG
    Mol Biol Cell; 2013 May; 24(9):1343-53. PubMed ID: 23468519
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks.
    Montales K; Ruis K; Lindsay H; Michael WM
    PLoS One; 2022; 17(8):e0271905. PubMed ID: 35917319
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.
    Takemura H; Rao VA; Sordet O; Furuta T; Miao ZH; Meng L; Zhang H; Pommier Y
    J Biol Chem; 2006 Oct; 281(41):30814-23. PubMed ID: 16905549
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks.
    Langerak P; Mejia-Ramirez E; Limbo O; Russell P
    PLoS Genet; 2011 Sep; 7(9):e1002271. PubMed ID: 21931565
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ATM and ATR promote Mre11 dependent restart of collapsed replication forks and prevent accumulation of DNA breaks.
    Trenz K; Smith E; Smith S; Costanzo V
    EMBO J; 2006 Apr; 25(8):1764-74. PubMed ID: 16601701
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR.
    Lee J; Kumagai A; Dunphy WG
    J Biol Chem; 2007 Sep; 282(38):28036-44. PubMed ID: 17636252
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA-damage-induced degradation of EXO1 exonuclease limits DNA end resection to ensure accurate DNA repair.
    Tomimatsu N; Mukherjee B; Harris JL; Boffo FL; Hardebeck MC; Potts PR; Khanna KK; Burma S
    J Biol Chem; 2017 Jun; 292(26):10779-10790. PubMed ID: 28515316
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The 9-1-1 Complex Controls Mre11 Nuclease and Checkpoint Activation during Short-Range Resection of DNA Double-Strand Breaks.
    Gobbini E; Casari E; Colombo CV; Bonetti D; Longhese MP
    Cell Rep; 2020 Oct; 33(3):108287. PubMed ID: 33086066
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of the signal transduction cascade for inflammatory gene expression in fibroblasts with ATM-ATR deficiencies after Ionizing radiation.
    Haruna S; Okuda K; Shibata A; Isono M; Tateno K; Sato H; Oike T; Uchihara Y; Kato Y; Shibata A
    Radiother Oncol; 2024 May; 194():110198. PubMed ID: 38438016
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Xenopus DNA2 is a helicase/nuclease that is found in complexes with replication proteins And-1/Ctf4 and Mcm10 and DSB response proteins Nbs1 and ATM.
    Wawrousek KE; Fortini BK; Polaczek P; Chen L; Liu Q; Dunphy WG; Campbell JL
    Cell Cycle; 2010 Mar; 9(6):1156-66. PubMed ID: 20237432
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template.
    Williams RS; Williams JS; Tainer JA
    Biochem Cell Biol; 2007 Aug; 85(4):509-20. PubMed ID: 17713585
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role for Rif1 in the checkpoint response to damaged DNA in Xenopus egg extracts.
    Kumar S; Yoo HY; Kumagai A; Shevchenko A; Shevchenko A; Dunphy WG
    Cell Cycle; 2012 Mar; 11(6):1183-94. PubMed ID: 22391207
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.