BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 38351373)

  • 1. Regulatory sites of CaM-sensitive adenylyl cyclase AC8 revealed by cryo-EM and structural proteomics.
    Khanppnavar B; Schuster D; Lavriha P; Uliana F; Özel M; Mehta V; Leitner A; Picotti P; Korkhov VM
    EMBO Rep; 2024 Mar; 25(3):1513-1540. PubMed ID: 38351373
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural insights into calmodulin/adenylyl cyclase 8 interaction.
    Herbst S; Masada N; Pfennig S; Ihling CH; Cooper DM; Sinz A
    Anal Bioanal Chem; 2013 Nov; 405(29):9333-42. PubMed ID: 24071896
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of FDA-Approved Small Molecules Capable of Disrupting the Calmodulin-Adenylyl Cyclase 8 Interaction through Direct Binding to Calmodulin.
    Hayes MP; Soto-Velasquez M; Fowler CA; Watts VJ; Roman DL
    ACS Chem Neurosci; 2018 Feb; 9(2):346-357. PubMed ID: 28968502
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Separate elements within a single IQ-like motif in adenylyl cyclase type 8 impart ca2+/calmodulin binding and autoinhibition.
    Macdougall DA; Wachten S; Ciruela A; Sinz A; Cooper DM
    J Biol Chem; 2009 Jun; 284(23):15573-88. PubMed ID: 19305019
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of calmodulin recruitment in Ca2+ stimulation of adenylyl cyclase type 8.
    Simpson RE; Ciruela A; Cooper DMF
    J Biol Chem; 2006 Jun; 281(25):17379-17389. PubMed ID: 16613843
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distinct mechanisms of regulation by Ca2+/calmodulin of type 1 and 8 adenylyl cyclases support their different physiological roles.
    Masada N; Ciruela A; Macdougall DA; Cooper DM
    J Biol Chem; 2009 Feb; 284(7):4451-63. PubMed ID: 19029295
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Residence of adenylyl cyclase type 8 in caveolae is necessary but not sufficient for regulation by capacitative Ca(2+) entry.
    Smith KE; Gu C; Fagan KA; Hu B; Cooper DM
    J Biol Chem; 2002 Feb; 277(8):6025-31. PubMed ID: 11744699
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural basis of adenylyl cyclase 9 activation.
    Qi C; Lavriha P; Mehta V; Khanppnavar B; Mohammed I; Li Y; Lazaratos M; Schaefer JV; Dreier B; Plückthun A; Bondar AN; Dessauer CW; Korkhov VM
    Nat Commun; 2022 Feb; 13(1):1045. PubMed ID: 35210418
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The type 8 adenylyl cyclase is critical for Ca2+ stimulation of cAMP accumulation in mouse parotid acini.
    Watson EL; Jacobson KL; Singh JC; Idzerda R; Ott SM; DiJulio DH; Wong ST; Storm DR
    J Biol Chem; 2000 May; 275(19):14691-9. PubMed ID: 10799557
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Distinct mechanisms of calmodulin binding and regulation of adenylyl cyclases 1 and 8.
    Masada N; Schaks S; Jackson SE; Sinz A; Cooper DM
    Biochemistry; 2012 Oct; 51(40):7917-29. PubMed ID: 22971080
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A Novel CRISPR/Cas9-Based Cellular Model to Explore Adenylyl Cyclase and cAMP Signaling.
    Soto-Velasquez M; Hayes MP; Alpsoy A; Dykhuizen EC; Watts VJ
    Mol Pharmacol; 2018 Sep; 94(3):963-972. PubMed ID: 29950405
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A direct interaction between the N terminus of adenylyl cyclase AC8 and the catalytic subunit of protein phosphatase 2A.
    Crossthwaite AJ; Ciruela A; Rayner TF; Cooper DM
    Mol Pharmacol; 2006 Feb; 69(2):608-17. PubMed ID: 16258073
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein.
    Qi C; Sorrentino S; Medalia O; Korkhov VM
    Science; 2019 Apr; 364(6438):389-394. PubMed ID: 31023924
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An extended conformation of calmodulin induces interactions between the structural domains of adenylyl cyclase from Bacillus anthracis to promote catalysis.
    Drum CL; Yan SZ; Sarac R; Mabuchi Y; Beckingham K; Bohm A; Grabarek Z; Tang WJ
    J Biol Chem; 2000 Nov; 275(46):36334-40. PubMed ID: 10926933
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Calcium-stimulated adenylyl cyclase activity is critical for hippocampus-dependent long-term memory and late phase LTP.
    Wong ST; Athos J; Figueroa XA; Pineda VV; Schaefer ML; Chavkin CC; Muglia LJ; Storm DR
    Neuron; 1999 Aug; 23(4):787-98. PubMed ID: 10482244
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Type 8 adenylyl cyclase is targeted to excitatory synapses and required for mossy fiber long-term potentiation.
    Wang H; Pineda VV; Chan GC; Wong ST; Muglia LJ; Storm DR
    J Neurosci; 2003 Oct; 23(30):9710-8. PubMed ID: 14585998
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Relationship among calmodulin-, forskolin-, and guanine nucleotide-dependent adenylate cyclase activities in cerebellar membranes: studies by limited proteolysis.
    Malnoë A; Cox JA
    J Neurochem; 1985 Oct; 45(4):1163-71. PubMed ID: 4040955
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A key phosphorylation site in AC8 mediates regulation of Ca(2+)-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complex.
    Willoughby D; Halls ML; Everett KL; Ciruela A; Skroblin P; Klussmann E; Cooper DM
    J Cell Sci; 2012 Dec; 125(Pt 23):5850-9. PubMed ID: 22976297
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Capacitative Ca2+ entry via Orai1 and stromal interacting molecule 1 (STIM1) regulates adenylyl cyclase type 8.
    Martin AC; Willoughby D; Ciruela A; Ayling LJ; Pagano M; Wachten S; Tengholm A; Cooper DM
    Mol Pharmacol; 2009 Apr; 75(4):830-42. PubMed ID: 19171672
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Copper and zinc inhibit Galphas function: a nucleotide-free state of Galphas induced by Cu2+ and Zn2+.
    Gao X; Du Z; Patel TB
    J Biol Chem; 2005 Jan; 280(4):2579-86. PubMed ID: 15546818
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.