BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 38356449)

  • 1. Effects of allopurinol on 6-mercaptopurine metabolism in unselected patients with pediatric acute lymphoblastic leukemia: a prospective phase II study.
    Källström J; Niinimäki R; Fredlund J; Vogt H; Korhonen L; Castor A; Palle J; Harila A; Borssén M; Abrahamsson J; Ek T
    Haematologica; 2024 Feb; ():. PubMed ID: 38356449
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of TPMT and ITPA variants in mercaptopurine disposition.
    Gerbek T; Ebbesen M; Nersting J; Frandsen TL; Appell ML; Schmiegelow K
    Cancer Chemother Pharmacol; 2018 Mar; 81(3):579-586. PubMed ID: 29387964
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allopurinol use during pediatric acute lymphoblastic leukemia maintenance therapy safely corrects skewed 6-mercaptopurine metabolism, improving inadequate myelosuppression and reducing gastrointestinal toxicity.
    Cohen G; Cooper S; Sison EA; Annesley C; Bhuiyan M; Brown P
    Pediatr Blood Cancer; 2020 Nov; 67(11):e28360. PubMed ID: 32909665
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Allopurinol Use During Maintenance Therapy for Acute Lymphoblastic Leukemia Avoids Mercaptopurine-related Hepatotoxicity.
    Giamanco NM; Cunningham BS; Klein LS; Parekh DS; Warwick AB; Lieuw K
    J Pediatr Hematol Oncol; 2016 Mar; 38(2):147-51. PubMed ID: 26808368
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Possible carcinogenic effect of 6-mercaptopurine on bone marrow stem cells: relation to thiopurine metabolism.
    Bo J; Schrøder H; Kristinsson J; Madsen B; Szumlanski C; Weinshilboum R; Andersen JB; Schmiegelow K
    Cancer; 1999 Sep; 86(6):1080-6. PubMed ID: 10491537
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Assessment on the use of allopurinol to improve safety and efficacy of mercaptopurine in pediatric patients with Acute Lymphoblastic Leukemia and Lymphoma during maintenance therapy.
    Barone T; Dandekar S; McKeone D; Mulieri K
    Cancer Rep (Hoboken); 2024 Feb; 7(2):e1987. PubMed ID: 38351548
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Assessment of mercaptopurine (6MP) metabolites and 6MP metabolic key-enzymes in childhood acute lymphoblastic leukemia.
    Wojtuszkiewicz A; Barcelos A; Dubbelman B; De Abreu R; Brouwer C; Bökkerink JP; de Haas V; de Groot-Kruseman H; Jansen G; Kaspers GL; Cloos J; Peters GJ
    Nucleosides Nucleotides Nucleic Acids; 2014; 33(4-6):422-33. PubMed ID: 24940700
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Utilization of Thiopurine Metabolites and Allopurinol in Pediatric Acute Lymphoblastic Leukemia: Consideration for an Algorithmic Approach.
    Mosher N; Torkildson J; Golden C; Raphael R; Beach B; Michlitsch J; Feusner JH; Agrawal AK
    J Pediatr Hematol Oncol; 2022 Mar; 44(2):e521-e525. PubMed ID: 34486570
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Allopurinol reverses mercaptopurine-induced hypoglycemia in patients with acute lymphoblastic leukemia.
    Zhang M; Bostrom B
    F1000Res; 2019; 8():176. PubMed ID: 30828444
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Allopurinol to Prevent Mercaptopurine Adverse Effects in Children and Young Adults With Acute Lymphoblastic Leukemia.
    Kamojjala R; Bostrom B
    J Pediatr Hematol Oncol; 2021 Apr; 43(3):95-100. PubMed ID: 33750748
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA-thioguanine nucleotide as a treatment marker in acute lymphoblastic leukemia patients with NUDT15 variant genotypes.
    Ju HY; Lee JW; Cho HW; Hyun JK; Ma Y; Yi ES; Yoo KH; Sung KW; Choi R; Koo HH; Lee SY
    PLoS One; 2021; 16(1):e0245667. PubMed ID: 33481917
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Possible implication of thiopurine S-methyltransferase in occurrence of infectious episodes during maintenance therapy for childhood lymphoblastic leukemia with mercaptopurine.
    Dervieux T; Médard Y; Verpillat P; Guigonis V; Duval M; Lescoeur B; Suciu S; Vilmer E; Jacqz-Aigrain E
    Leukemia; 2001 Nov; 15(11):1706-12. PubMed ID: 11681411
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thiopurine Methyltransferase Intermediate Metabolizer Status and Thiopurine-Associated Toxicity During Maintenance Therapy in Childhood Acute Lymphoblastic Leukemia.
    Schwarz UI; Woldanski-Travaglini M; Swanston V; Mikhail M; Cacciotti C; Cairney E; Patel S; Seelisch J; Tole S; Wilejto M; Tirona RG; Kim RB; Zorzi AP
    Clin Pharmacol Ther; 2023 Jun; 113(6):1326-1336. PubMed ID: 36932910
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thiopurine methyltransferase deficiency in childhood lymphoblastic leukaemia: 6-mercaptopurine dosage strategies.
    Lennard L; Lewis IJ; Michelagnoli M; Lilleyman JS
    Med Pediatr Oncol; 1997 Oct; 29(4):252-5. PubMed ID: 9251729
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Myelotoxicity after high-dose methotrexate in childhood acute leukemia is influenced by 6-mercaptopurine dosing but not by intermediate thiopurine methyltransferase activity.
    Levinsen M; Rosthøj S; Nygaard U; Heldrup J; Harila-Saari A; Jonsson OG; Bechensteen AG; Abrahamsson J; Lausen B; Frandsen TL; Weinshilboum RM; Schmiegelow K
    Cancer Chemother Pharmacol; 2015 Jan; 75(1):59-66. PubMed ID: 25347948
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA-thioguanine nucleotide concentration and relapse-free survival during maintenance therapy of childhood acute lymphoblastic leukaemia (NOPHO ALL2008): a prospective substudy of a phase 3 trial.
    Nielsen SN; Grell K; Nersting J; Abrahamsson J; Lund B; Kanerva J; Jónsson ÓG; Vaitkeviciene G; Pruunsild K; Hjalgrim LL; Schmiegelow K
    Lancet Oncol; 2017 Apr; 18(4):515-524. PubMed ID: 28258828
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Use of allopurinol in children with acute lymphoblastic leukemia to reduce skewed thiopurine metabolism.
    Brackett J; Schafer ES; Leung DH; Bernhardt MB
    Pediatr Blood Cancer; 2014 Jun; 61(6):1114-7. PubMed ID: 24376133
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pharmacokinetics and metabolism of thiopurines in children with acute lymphoblastic leukemia receiving 6-thioguanine versus 6-mercaptopurine.
    Erb N; Harms DO; Janka-Schaub G
    Cancer Chemother Pharmacol; 1998; 42(4):266-72. PubMed ID: 9744770
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Maintenance therapy for acute lymphoblastic leukemia: basic science and clinical translations.
    Toksvang LN; Lee SHR; Yang JJ; Schmiegelow K
    Leukemia; 2022 Jul; 36(7):1749-1758. PubMed ID: 35654820
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Thiopurine Enhanced ALL Maintenance (TEAM): study protocol for a randomized study to evaluate the improvement in disease-free survival by adding very low dose 6-thioguanine to 6-mercaptopurine/methotrexate-based maintenance therapy in pediatric and adult patients (0-45 years) with newly diagnosed B-cell precursor or T-cell acute lymphoblastic leukemia treated according to the intermediate risk-high group of the ALLTogether1 protocol.
    Toksvang LN; Als-Nielsen B; Bacon C; Bertasiute R; Duarte X; Escherich G; Helgadottir EA; Johannsdottir IR; Jónsson ÓG; Kozlowski P; Langenskjöld C; Lepik K; Niinimäki R; Overgaard UM; Punab M; Räty R; Segers H; van der Sluis I; Smith OP; Strullu M; Vaitkevičienė G; Wik HS; Heyman M; Schmiegelow K
    BMC Cancer; 2022 May; 22(1):483. PubMed ID: 35501736
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.