126 related articles for article (PubMed ID: 38369668)
1. The positive allosteric modulator BPAM344 and L-glutamate introduce an active-like structure of the ligand-binding domain of GluK2.
Bay Y; Egeberg Jeppesen M; Frydenvang K; Francotte P; Pirotte B; Pickering DS; Kristensen AS; Kastrup JS
FEBS Lett; 2024 Apr; 598(7):743-757. PubMed ID: 38369668
[TBL] [Abstract][Full Text] [Related]
2. Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure.
Bay Y; Venskutonytė R; Frantsen SM; Thorsen TS; Musgaard M; Frydenvang K; Francotte P; Pirotte B; Biggin PC; Kristensen AS; Boesen T; Pickering DS; Gajhede M; Kastrup JS
FEBS J; 2024 Apr; 291(7):1506-1529. PubMed ID: 38145505
[TBL] [Abstract][Full Text] [Related]
3. Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanel.
Gangwar SP; Yen LY; Yelshanskaya MV; Sobolevsky AI
Cell Rep; 2023 Feb; 42(2):112124. PubMed ID: 36857176
[TBL] [Abstract][Full Text] [Related]
4. Kainate receptor channel opening and gating mechanism.
Gangwar SP; Yelshanskaya MV; Nadezhdin KD; Yen LY; Newton TP; Aktolun M; Kurnikova MG; Sobolevsky AI
Nature; 2024 Jun; 630(8017):762-768. PubMed ID: 38778115
[TBL] [Abstract][Full Text] [Related]
5. Correlating efficacy and desensitization with GluK2 ligand-binding domain movements.
Nayeem N; Mayans O; Green T
Open Biol; 2013 May; 3(5):130051. PubMed ID: 23720540
[TBL] [Abstract][Full Text] [Related]
6. Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors.
Larsen AP; Fièvre S; Frydenvang K; Francotte P; Pirotte B; Kastrup JS; Mulle C
Mol Pharmacol; 2017 Jun; 91(6):576-585. PubMed ID: 28360094
[TBL] [Abstract][Full Text] [Related]
7. Binding and selectivity of the marine toxin neodysiherbaine A and its synthetic analogues to GluK1 and GluK2 kainate receptors.
Unno M; Shinohara M; Takayama K; Tanaka H; Teruya K; Doh-ura K; Sakai R; Sasaki M; Ikeda-Saito M
J Mol Biol; 2011 Oct; 413(3):667-83. PubMed ID: 21893069
[TBL] [Abstract][Full Text] [Related]
8. Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate.
Venskutonytė R; Frydenvang K; Gajhede M; Bunch L; Pickering DS; Kastrup JS
J Struct Biol; 2011 Dec; 176(3):307-14. PubMed ID: 21907808
[TBL] [Abstract][Full Text] [Related]
9. Assembly and Trafficking of Homomeric and Heteromeric Kainate Receptors with Impaired Ligand Binding Sites.
Scholefield CL; Atlason PT; Jane DE; Molnár E
Neurochem Res; 2019 Mar; 44(3):585-599. PubMed ID: 30302614
[TBL] [Abstract][Full Text] [Related]
10. Neto proteins regulate gating of the kainate-type glutamate receptor GluK2 through two binding sites.
Li YJ; Duan GF; Sun JH; Wu D; Ye C; Zang YY; Chen GQ; Shi YY; Wang J; Zhang W; Shi YS
J Biol Chem; 2019 Nov; 294(47):17889-17902. PubMed ID: 31628192
[TBL] [Abstract][Full Text] [Related]
11. Lessons from crystal structures of kainate receptors.
Møllerud S; Frydenvang K; Pickering DS; Kastrup JS
Neuropharmacology; 2017 Jan; 112(Pt A):16-28. PubMed ID: 27236079
[TBL] [Abstract][Full Text] [Related]
12. Domain organization and function in GluK2 subtype kainate receptors.
Das U; Kumar J; Mayer ML; Plested AJ
Proc Natl Acad Sci U S A; 2010 May; 107(18):8463-8. PubMed ID: 20404149
[TBL] [Abstract][Full Text] [Related]
13. High Conformational Variability in the GluK2 Kainate Receptor Ligand-Binding Domain.
Wied TJ; Chin AC; Lau AY
Structure; 2019 Jan; 27(1):189-195.e2. PubMed ID: 30482727
[TBL] [Abstract][Full Text] [Related]
14. Conformational flexibility of the ligand-binding domain dimer in kainate receptor gating and desensitization.
Nayeem N; Mayans O; Green T
J Neurosci; 2011 Feb; 31(8):2916-24. PubMed ID: 21414913
[TBL] [Abstract][Full Text] [Related]
15. Energetics of glutamate receptor ligand binding domain dimer assembly are modulated by allosteric ions.
Chaudhry C; Plested AJ; Schuck P; Mayer ML
Proc Natl Acad Sci U S A; 2009 Jul; 106(30):12329-34. PubMed ID: 19617541
[TBL] [Abstract][Full Text] [Related]
16. Functional Validation of Heteromeric Kainate Receptor Models.
Paramo T; Brown PMGE; Musgaard M; Bowie D; Biggin PC
Biophys J; 2017 Nov; 113(10):2173-2177. PubMed ID: 28935133
[TBL] [Abstract][Full Text] [Related]
17. The Structure of a High-Affinity Kainate Receptor: GluK4 Ligand-Binding Domain Crystallized with Kainate.
Kristensen O; Kristensen LB; Møllerud S; Frydenvang K; Pickering DS; Kastrup JS
Structure; 2016 Sep; 24(9):1582-9. PubMed ID: 27524200
[TBL] [Abstract][Full Text] [Related]
18. Identification of critical functional determinants of kainate receptor modulation by auxiliary protein Neto2.
Griffith TN; Swanson GT
J Physiol; 2015 Nov; 593(22):4815-33. PubMed ID: 26282342
[TBL] [Abstract][Full Text] [Related]
19. Agonist binding to the GluK5 subunit is sufficient for functional surface expression of heteromeric GluK2/GluK5 kainate receptors.
Fisher JL; Housley PR
Cell Mol Neurobiol; 2013 Nov; 33(8):1099-108. PubMed ID: 23975096
[TBL] [Abstract][Full Text] [Related]
20. Modulation of homomeric and heteromeric kainate receptors by the auxiliary subunit Neto1.
Fisher JL; Mott DD
J Physiol; 2013 Oct; 591(19):4711-24. PubMed ID: 23798491
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]