These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 38372781)

  • 1. Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials.
    Gilleran JA; Ashraf K; Delvillar M; Eck T; Fondekar R; Miller EB; Hutchinson A; Dong A; Seitova A; De Souza ML; Augeri D; Halabelian L; Siekierka J; Rotella DP; Gordon J; Childers WE; Grier MC; Staker BL; Roberge JY; Bhanot P
    J Med Chem; 2024 Mar; 67(5):3467-3503. PubMed ID: 38372781
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of Plasmodium falciparum cGMP-dependent protein kinase (PfPKG): antiparasitic activity of a PKG inhibitor.
    Diaz CA; Allocco J; Powles MA; Yeung L; Donald RG; Anderson JW; Liberator PA
    Mol Biochem Parasitol; 2006 Mar; 146(1):78-88. PubMed ID: 16325279
    [TBL] [Abstract][Full Text] [Related]  

  • 3.
    Govindasamy K; Khan R; Snyder M; Lou HJ; Du P; Kudyba HM; Muralidharan V; Turk BE; Bhanot P
    Infect Immun; 2019 Jan; 87(1):. PubMed ID: 30323024
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The malaria parasite cyclic GMP-dependent protein kinase plays a central role in blood-stage schizogony.
    Taylor HM; McRobert L; Grainger M; Sicard A; Dluzewski AR; Hopp CS; Holder AA; Baker DA
    Eukaryot Cell; 2010 Jan; 9(1):37-45. PubMed ID: 19915077
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Trisubstituted thiazoles as potent and selective inhibitors of Plasmodium falciparum protein kinase G (PfPKG).
    Tsagris DJ; Birchall K; Bouloc N; Large JM; Merritt A; Smiljanic-Hurley E; Wheldon M; Ansell KH; Kettleborough C; Whalley D; Stewart LB; Bowyer PW; Baker DA; Osborne SA
    Bioorg Med Chem Lett; 2018 Oct; 28(19):3168-3173. PubMed ID: 30174152
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Development of a transgenic Plasmodium berghei line (Pb pfpkg) expressing the P. falciparum cGMP-dependent protein kinase, a novel antimalarial drug target.
    Tewari R; Patzewitz EM; Poulin B; Stewart L; Baker DA
    PLoS One; 2014; 9(5):e96923. PubMed ID: 24805991
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase.
    Hopp CS; Flueck C; Solyakov L; Tobin A; Baker DA
    PLoS One; 2012; 7(11):e48206. PubMed ID: 23139764
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of allosteric inhibition in the
    Byun JA; Van K; Huang J; Henning P; Franz E; Akimoto M; Herberg FW; Kim C; Melacini G
    J Biol Chem; 2020 Jun; 295(25):8480-8491. PubMed ID: 32317283
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of Competitive Inhibitors of Plasmodium falciparum cGMP-Dependent Protein Kinase.
    Eck T; Laureano de Souza M; Delvillar M; Ashraf K; Yadav Bheemanaboina RR; Chakrasali R; Kreiss T; Siekierka JJ; Rotella DP; Bhanot P; Goodey NM
    Chembiochem; 2022 Apr; 23(7):e202100704. PubMed ID: 35044710
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Divergent allostery reveals critical differences between structurally homologous regulatory domains of Plasmodium falciparum and human protein kinase G.
    Byun JA; VanSchouwen B; Huang J; Baryar U; Melacini G
    J Biol Chem; 2022 Mar; 298(3):101691. PubMed ID: 35143840
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Potent inhibitors of malarial P. Falciparum protein kinase G: Improving the cell activity of a series of imidazopyridines.
    Large JM; Birchall K; Bouloc NS; Merritt AT; Smiljanic-Hurley E; Tsagris DJ; Wheldon MC; Ansell KH; Coombs PJ; Kettleborough CA; Whalley D; Stewart LB; Bowyer PW; Baker DA; Osborne SA
    Bioorg Med Chem Lett; 2019 Feb; 29(3):509-514. PubMed ID: 30553738
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Screening the Pathogen Box for Inhibition of Plasmodium falciparum Sporozoite Motility Reveals a Critical Role for Kinases in Transmission Stages.
    Kanatani S; Elahi R; Kanchanabhogin S; Vartak N; Tripathi AK; Prigge ST; Sinnis P
    Antimicrob Agents Chemother; 2022 Sep; 66(9):e0041822. PubMed ID: 35943271
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A New Thienopyrimidinone Chemotype Shows Multistage Activity against Plasmodium falciparum, Including Artemisinin-Resistant Parasites.
    Bosson-Vanga H; Primas N; Franetich JF; Lavazec C; Gomez L; Ashraf K; Tefit M; Soulard V; Dereuddre-Bosquet N; Le Grand R; Donnette M; Mustière R; Amanzougaghene N; Tajeri S; Suzanne P; Malzert-Fréon A; Rault S; Vanelle P; Hutter S; Cohen A; Snounou G; Roques P; Azas N; Lagardère P; Lisowski V; Masurier N; Nguyen M; Paloque L; Benoit-Vical F; Verhaeghe P; Mazier D
    Microbiol Spectr; 2021 Oct; 9(2):e0027421. PubMed ID: 34724729
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites.
    Verlinden BK; de Beer M; Pachaiyappan B; Besaans E; Andayi WA; Reader J; Niemand J; van Biljon R; Guy K; Egan T; Woster PM; Birkholtz LM
    Bioorg Med Chem; 2015 Aug; 23(16):5131-43. PubMed ID: 25684422
    [TBL] [Abstract][Full Text] [Related]  

  • 15. cGMP Binding Domain D Mediates a Unique Activation Mechanism in Plasmodium falciparum PKG.
    Franz E; Knape MJ; Herberg FW
    ACS Infect Dis; 2018 Mar; 4(3):415-423. PubMed ID: 29251493
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Antiplasmodial dihetarylthioethers target the coenzyme A synthesis pathway in Plasmodium falciparum erythrocytic stages.
    Weidner T; Lucantoni L; Nasereddin A; Preu L; Jones PG; Dzikowski R; Avery VM; Kunick C
    Malar J; 2017 May; 16(1):192. PubMed ID: 28502250
    [TBL] [Abstract][Full Text] [Related]  

  • 17.
    Rotella D; Siekierka J; Bhanot P
    Front Microbiol; 2020; 11():610408. PubMed ID: 33613463
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development.
    Green JL; Moon RW; Whalley D; Bowyer PW; Wallace C; Rochani A; Nageshan RK; Howell SA; Grainger M; Jones HM; Ansell KH; Chapman TM; Taylor DL; Osborne SA; Baker DA; Tatu U; Holder AA
    Antimicrob Agents Chemother; 2015 Dec; 60(3):1464-75. PubMed ID: 26711771
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification and characterization of the antiplasmodial activity of Hsp90 inhibitors.
    Murillo-Solano C; Dong C; Sanchez CG; Pizarro JC
    Malar J; 2017 Jul; 16(1):292. PubMed ID: 28724415
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of Imidazole-Based Inhibitors of
    Bheemanaboina RRY; de Souza ML; Gonzalez ML; Mahmood SU; Eck T; Kreiss T; Aylor SO; Roth A; Lee P; Pybus BS; Colussi DJ; Childers WE; Gordon J; Siekierka JJ; Bhanot P; Rotella DP
    ACS Med Chem Lett; 2021 Dec; 12(12):1962-1967. PubMed ID: 34917261
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.