BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 38375594)

  • 1. A novel HDAC6 inhibitor interferes microtubule dynamics and spindle assembly checkpoint and sensitizes cisplatin-induced apoptosis in castration-resistant prostate cancer.
    Ye PC; Leu WJ; Yeh TY; Hsu YT; Lin YC; Wei ZY; Chen YC; Chiang YC; Hsu JL; Chan SH; Hsu LC; Chern JW; Yu CW; Guh JH
    Prostate; 2024 May; 84(6):605-619. PubMed ID: 38375594
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway.
    Ho CH; Hsu JL; Liu SP; Hsu LC; Chang WL; Chao CC; Guh JH
    Prostate; 2015 Sep; 75(13):1454-66. PubMed ID: 26180030
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mechanistic study of dual-function inhibitors targeting topoisomerase II and Rad51-mediated DNA repair pathway against castration-resistant prostate cancer.
    Chiang YC; Leu WJ; Chen YC; Ye PC; Hsu YT; Hsiao YC; Hsu JL; Chan SH; Hsu LC; Huang HS; Guh JH
    Prostate; 2023 Dec; 83(16):1549-1563. PubMed ID: 37583103
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ascleposide, a natural cardenolide, induces anticancer signaling in human castration-resistant prostatic cancer through Na
    Leu WJ; Wang CT; Hsu JL; Chen IS; Chang HS; Guh JH
    Prostate; 2020 Mar; 80(4):305-318. PubMed ID: 31905252
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CIL-102 interacts with microtubule polymerization and causes mitotic arrest following apoptosis in the human prostate cancer PC-3 cell line.
    Huang YT; Huang DM; Guh JH; Chen IL; Tzeng CC; Teng CM
    J Biol Chem; 2005 Jan; 280(4):2771-9. PubMed ID: 15536083
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Androgen receptor negatively regulates mitotic checkpoint signaling to induce docetaxel resistance in castration-resistant prostate cancer.
    Pilling A; Kim SH; Hwang C
    Prostate; 2022 Feb; 82(2):182-192. PubMed ID: 34672379
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 6,7-Dimethoxy-3-(3-methoxyphenyl)isoquinolin-1-amine induces mitotic arrest and apoptotic cell death through the activation of spindle assembly checkpoint in human cervical cancer cells.
    Chung KS; Choi HE; Shin JS; Cho YW; Choi JH; Cho WJ; Lee KT
    Carcinogenesis; 2013 Aug; 34(8):1852-60. PubMed ID: 23615402
    [TBL] [Abstract][Full Text] [Related]  

  • 8. EGFR-mediated hyperacetylation of tubulin induced docetaxel resistance by downregulation of HDAC6 and upregulation of MCAK and PLK1 in prostate cancer cells.
    Pu YS; Huang CY; Wu HL; Wu JH; Su YF; Yu CR; Lu CY; Wu WJ; Huang SP; Huang YT; Hour TC
    Kaohsiung J Med Sci; 2024 Jan; 40(1):23-34. PubMed ID: 37916740
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of histone deacetylase 6 destabilizes ERK phosphorylation and suppresses cancer proliferation via modulation of the tubulin acetylation-GRP78 interaction.
    Wattanathamsan O; Chantaravisoot N; Wongkongkathep P; Kungsukool S; Chetprayoon P; Chanvorachote P; Vinayanuwattikun C; Pongrakhananon V
    J Biomed Sci; 2023 Jan; 30(1):4. PubMed ID: 36639650
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 2-Phenyl-5-(pyrrolidin-1-yl)-1-(3,4,5-trimethoxybenzyl)-1H-benzimidazole, a benzimidazole derivative, inhibits growth of human prostate cancer cells by affecting tubulin and c-Jun N-terminal kinase.
    Chang WL; Chang CS; Chiang PC; Ho YF; Liu JF; Chang KW; Guh JH
    Br J Pharmacol; 2010 Aug; 160(7):1677-89. PubMed ID: 20649571
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MeCP2 deficiency is associated with reduced levels of tubulin acetylation and can be restored using HDAC6 inhibitors.
    Gold WA; Lacina TA; Cantrill LC; Christodoulou J
    J Mol Med (Berl); 2015 Jan; 93(1):63-72. PubMed ID: 25209898
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel CIL-102 derivatives as potential therapeutic agents for docetaxel-resistant prostate cancer.
    Miller DR; Tzeng CC; Farmer T; Keller ET; Caplan S; Chen YS; Chen YL; Lin MF
    Cancer Lett; 2018 Nov; 436():96-108. PubMed ID: 30077739
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The newly synthesized 2-arylnaphthyridin-4-one, CSC-3436, induces apoptosis of non-small cell lung cancer cells by inhibiting tubulin dynamics and activating CDK1.
    Chang LC; Yu YL; Liu CY; Cheng YY; Chou RH; Hsieh MT; Lin HY; Hung HY; Huang LJ; Wu YC; Kuo SC
    Cancer Chemother Pharmacol; 2015 Jun; 75(6):1303-15. PubMed ID: 25947085
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of HDAC6 deacetylase activity increases its binding with microtubules and suppresses microtubule dynamic instability in MCF-7 cells.
    Asthana J; Kapoor S; Mohan R; Panda D
    J Biol Chem; 2013 Aug; 288(31):22516-26. PubMed ID: 23798680
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel small molecule hybrid of vorinostat and DACA displays anticancer activity against human hormone-refractory metastatic prostate cancer through dual inhibition of histone deacetylase and topoisomerase I.
    Yu CC; Pan SL; Chao SW; Liu SP; Hsu JL; Yang YC; Li TK; Huang WJ; Guh JH
    Biochem Pharmacol; 2014 Aug; 90(3):320-30. PubMed ID: 24915421
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An antitubulin agent BCFMT inhibits proliferation of cancer cells and induces cell death by inhibiting microtubule dynamics.
    Rai A; Surolia A; Panda D
    PLoS One; 2012; 7(8):e44311. PubMed ID: 22952952
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of HDAC6 by tubastatin A disrupts mouse oocyte meiosis via regulating histone modifications and mRNA expression.
    Sui L; Huang R; Yu H; Zhang S; Li Z
    J Cell Physiol; 2020 Oct; 235(10):7030-7042. PubMed ID: 32017059
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of cell migration and induction of apoptosis by a novel class II histone deacetylase inhibitor, MCC2344.
    Dawood M; Fleischer E; Klinger A; Bringmann G; Shan L; Efferth T
    Pharmacol Res; 2020 Oct; 160():105076. PubMed ID: 32659428
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacological inhibition of HDAC6 overcomes cisplatin chemoresistance by targeting cancer stem cells in oral squamous cell carcinoma.
    Tavares MO; Milan TM; Bighetti-Trevisan RL; Leopoldino AM; de Almeida LO
    J Oral Pathol Med; 2022 Jul; 51(6):529-537. PubMed ID: 35678235
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chelidonine induces mitotic slippage and apoptotic-like death in SGC-7901 human gastric carcinoma cells.
    Qu Z; Zou X; Zhang X; Sheng J; Wang Y; Wang J; Wang C; Ji Y
    Mol Med Rep; 2016 Feb; 13(2):1336-44. PubMed ID: 26677104
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.