BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 38386898)

  • 1. Modifications of Protein-Bound Substrates by Trans-Acting Enzymes in Natural Products Biosynthesis.
    Skala LE; Philmus B; Mahmud T
    Chembiochem; 2024 Apr; 25(8):e202400056. PubMed ID: 38386898
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modular Halogenation, α-Hydroxylation, and Acylation by a Remarkably Versatile Polyketide Synthase.
    Hemmerling F; Meoded RA; Fraley AE; Minas HA; Dieterich CL; Rust M; Ueoka R; Jensen K; Helfrich EJN; Bergande C; Biedermann M; Magnus N; Piechulla B; Piel J
    Angew Chem Int Ed Engl; 2022 Mar; 61(11):e202116614. PubMed ID: 35020279
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glycosylation of acyl carrier protein-bound polyketides during pactamycin biosynthesis.
    Eida AA; Abugrain ME; Brumsted CJ; Mahmud T
    Nat Chem Biol; 2019 Aug; 15(8):795-802. PubMed ID: 31308531
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Recognition of acyl carrier proteins by ketoreductases in assembly line polyketide synthases.
    Ostrowski MP; Cane DE; Khosla C
    J Antibiot (Tokyo); 2016 Jul; 69(7):507-10. PubMed ID: 27118242
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural Basis of Protein-Protein Interactions between a trans-Acting Acyltransferase and Acyl Carrier Protein in Polyketide Disorazole Biosynthesis.
    Miyanaga A; Ouchi R; Ishikawa F; Goto E; Tanabe G; Kudo F; Eguchi T
    J Am Chem Soc; 2018 Jun; 140(25):7970-7978. PubMed ID: 29870659
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones.
    Meoded RA; Ueoka R; Helfrich EJN; Jensen K; Magnus N; Piechulla B; Piel J
    Angew Chem Int Ed Engl; 2018 Sep; 57(36):11644-11648. PubMed ID: 29898240
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Anatomy of the β-branching enzyme of polyketide biosynthesis and its interaction with an acyl-ACP substrate.
    Maloney FP; Gerwick L; Gerwick WH; Sherman DH; Smith JL
    Proc Natl Acad Sci U S A; 2016 Sep; 113(37):10316-21. PubMed ID: 27573844
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Protein-protein recognition between acyltransferases and acyl carrier proteins in multimodular polyketide synthases.
    Wong FT; Chen AY; Cane DE; Khosla C
    Biochemistry; 2010 Jan; 49(1):95-102. PubMed ID: 19921859
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural and Biochemical Analysis of Protein-Protein Interactions Between the Acyl-Carrier Protein and Product Template Domain.
    Barajas JF; Finzel K; Valentic TR; Shakya G; Gamarra N; Martinez D; Meier JL; Vagstad AL; Newman AG; Townsend CA; Burkart MD; Tsai SC
    Angew Chem Int Ed Engl; 2016 Oct; 55(42):13005-13009. PubMed ID: 27653519
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of Unexpected Self-Acylation Activity of Acyl Carrier Proteins in a Modular Type I Apicomplexan Polyketide Synthase.
    Keeler AM; D'Ambrosio HK; Ganley JG; Derbyshire ER
    ACS Chem Biol; 2023 Apr; 18(4):785-793. PubMed ID: 36893402
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The stereochemistry of complex polyketide biosynthesis by modular polyketide synthases.
    Kwan DH; Schulz F
    Molecules; 2011 Jul; 16(7):6092-115. PubMed ID: 21775938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. How Acyl Carrier Proteins (ACPs) Direct Fatty Acid and Polyketide Biosynthesis.
    Buyachuihan L; Stegemann F; Grininger M
    Angew Chem Int Ed Engl; 2024 Jan; 63(4):e202312476. PubMed ID: 37856285
    [TBL] [Abstract][Full Text] [Related]  

  • 13. De Novo Design and Implementation of a Tandem Acyl Carrier Protein Domain in a Type I Modular Polyketide Synthase.
    Wang Z; Bagde SR; Zavala G; Matsui T; Chen X; Kim CY
    ACS Chem Biol; 2018 Nov; 13(11):3072-3077. PubMed ID: 30354045
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Comparative analysis of the substrate specificity of trans- versus cis-acyltransferases of assembly line polyketide synthases.
    Dunn BJ; Watts KR; Robbins T; Cane DE; Khosla C
    Biochemistry; 2014 Jun; 53(23):3796-806. PubMed ID: 24871074
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enzymes involved in fatty acid and polyketide biosynthesis in Streptomyces glaucescens: role of FabH and FabD and their acyl carrier protein specificity.
    Florova G; Kazanina G; Reynolds KA
    Biochemistry; 2002 Aug; 41(33):10462-71. PubMed ID: 12173933
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural visualization of transient interactions between the cis-acting acyltransferase and acyl carrier protein of the salinomycin modular polyketide synthase.
    Feng Y; Zhang F; Huang S; Deng Z; Bai L; Zheng J
    Acta Crystallogr D Struct Biol; 2022 Jun; 78(Pt 6):779-791. PubMed ID: 35647924
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural rearrangements of a polyketide synthase module during its catalytic cycle.
    Whicher JR; Dutta S; Hansen DA; Hale WA; Chemler JA; Dosey AM; Narayan AR; Håkansson K; Sherman DH; Smith JL; Skiniotis G
    Nature; 2014 Jun; 510(7506):560-4. PubMed ID: 24965656
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prediction of inter domain interactions in modular polyketide synthases by docking and correlated mutation analysis.
    Yadav G; Anand S; Mohanty D
    J Biomol Struct Dyn; 2013; 31(1):17-29. PubMed ID: 22803697
    [TBL] [Abstract][Full Text] [Related]  

  • 19. On-line enzymatic tailoring of polyketides and peptides in thiotemplate systems.
    Sundaram S; Hertweck C
    Curr Opin Chem Biol; 2016 Apr; 31():82-94. PubMed ID: 26859622
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Engineered Chimeras Unveil Swappable Modular Features of Fatty Acid and Polyketide Synthase Acyl Carrier Proteins.
    Cho YI; Armstrong CL; Sulpizio A; Acheampong KK; Banks KN; Bardhan O; Churchill SJ; Connolly-Sporing AE; Crawford CEW; Cruz Parrilla PL; Curtis SM; De La Ossa LM; Epstein SC; Farrehi CJ; Hamrick GS; Hillegas WJ; Kang A; Laxton OC; Ling J; Matsumura SM; Merino VM; Mukhtar SH; Shah NJ; Londergan CH; Daly CA; Kokona B; Charkoudian LK
    Biochemistry; 2022 Feb; 61(4):217-227. PubMed ID: 35073057
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.