These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 38387340)

  • 1. Automated high-throughput buffer exchange platform enhances rapid flow analysis of antibody drug conjugates by high resolution mass spectrometry.
    Yang Y; Rao R; Valliere-Douglass J; Tremintin G
    J Chromatogr B Analyt Technol Biomed Life Sci; 2024 Mar; 1235():124007. PubMed ID: 38387340
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Native size-exclusion chromatography-mass spectrometry: suitability for antibody-drug conjugate drug-to-antibody ratio quantitation across a range of chemotypes and drug-loading levels.
    Jones J; Pack L; Hunter JH; Valliere-Douglass JF
    MAbs; 2020; 12(1):1682895. PubMed ID: 31769727
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A native SEC-MS workflow and validation for analyzing drug-to-antibody ratio and drug load distribution in cysteine-linked antibody-drug conjugates.
    Wu G; Yu C; Yin S; Du J; Zhang Y; Fu Z; Wang L; Wang J
    J Chromatogr B Analyt Technol Biomed Life Sci; 2024 Jul; 1241():124167. PubMed ID: 38823148
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [The Characterization of Drug-to-Antibody Ratio and Isoforms of ADCs Using LC and MS Technologies].
    Iizuka R; Kotch F; Xu A; Porter T; Shion H; Birdsall R; Chen W
    Yakugaku Zasshi; 2017; 137(5):525-528. PubMed ID: 28458283
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A rapid on-line method for mass spectrometric confirmation of a cysteine-conjugated antibody-drug-conjugate structure using multidimensional chromatography.
    Birdsall RE; Shion H; Kotch FW; Xu A; Porter TJ; Chen W
    MAbs; 2015; 7(6):1036-44. PubMed ID: 26305867
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Innovative native MS methodologies for antibody drug conjugate characterization: High resolution native MS and IM-MS for average DAR and DAR distribution assessment.
    Debaene F; Boeuf A; Wagner-Rousset E; Colas O; Ayoub D; Corvaïa N; Van Dorsselaer A; Beck A; Cianférani S
    Anal Chem; 2014 Nov; 86(21):10674-83. PubMed ID: 25270580
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analysis of ADCs by Native Mass Spectrometry.
    Hernandez-Alba O; Ehkirch A; Beck A; Cianférani S
    Methods Mol Biol; 2020; 2078():197-211. PubMed ID: 31643058
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. I - Optimization of separation conditions.
    Sarrut M; Corgier A; Fekete S; Guillarme D; Lascoux D; Janin-Bussat MC; Beck A; Heinisch S
    J Chromatogr B Analyt Technol Biomed Life Sci; 2016 Oct; 1032():103-111. PubMed ID: 27426266
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Is hydrophobic interaction chromatography the most suitable technique to characterize site-specific antibody-drug conjugates?
    D'Atri V; Pell R; Clarke A; Guillarme D; Fekete S
    J Chromatogr A; 2019 Feb; 1586():149-153. PubMed ID: 30554777
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hydrophobic interaction chromatography (HIC) method development and characterization of resolved drug-load variants in site-specifically conjugated pyrrolobenzodiazepine dimer-based antibody drug conjugates (PBD-ADCs).
    Janaratne T; Wang XC; Becker C; Zhao Y; Leanna R; Pritts W
    J Pharm Biomed Anal; 2020 Feb; 179():113027. PubMed ID: 31830625
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Application of triple quadrupole mass spectrometry for the characterization of antibody-drug conjugates.
    Källsten M; Pijnappel M; Hartmann R; Lehmann F; Kovac L; Lind SB; Bergquist J
    Anal Bioanal Chem; 2019 May; 411(12):2569-2576. PubMed ID: 30848315
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Analysis of antibody-drug conjugates by comprehensive on-line two-dimensional hydrophobic interaction chromatography x reversed phase liquid chromatography hyphenated to high resolution mass spectrometry. II- Identification of sub-units for the characterization of even and odd load drug species.
    Sarrut M; Fekete S; Janin-Bussat MC; Colas O; Guillarme D; Beck A; Heinisch S
    J Chromatogr B Analyt Technol Biomed Life Sci; 2016 Oct; 1032():91-102. PubMed ID: 27426265
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Practical approaches for overcoming challenges in heightened characterization of antibody-drug conjugates with new methodologies and ultrahigh-resolution mass spectrometry.
    Friese OV; Smith JN; Brown PW; Rouse JC
    MAbs; 2018 Apr; 10(3):335-345. PubMed ID: 29393747
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Two-Dimensional Liquid Chromatography Coupled to High-Resolution Mass Spectrometry for the Analysis of ADCs.
    Chapel S; Rouvière F; Sarrut M; Heinisch S
    Methods Mol Biol; 2020; 2078():163-185. PubMed ID: 31643056
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Qualitative analysis of antibody-drug conjugates (ADCs): an experimental comparison of analytical techniques of cysteine-linked ADCs.
    Källsten M; Hartmann R; Artemenko K; Lind SB; Lehmann F; Bergquist J
    Analyst; 2018 Nov; 143(22):5487-5496. PubMed ID: 30289422
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of drug load variants in a thiol linked antibody-drug conjugate using multidimensional chromatography.
    Gilroy JJ; Eakin CM
    J Chromatogr B Analyt Technol Biomed Life Sci; 2017 Aug; 1060():182-189. PubMed ID: 28622622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Native mass spectrometry and ion mobility characterization of trastuzumab emtansine, a lysine-linked antibody drug conjugate.
    Marcoux J; Champion T; Colas O; Wagner-Rousset E; Corvaïa N; Van Dorsselaer A; Beck A; Cianférani S
    Protein Sci; 2015 Aug; 24(8):1210-23. PubMed ID: 25694334
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Current possibilities of liquid chromatography for the characterization of antibody-drug conjugates.
    Bobály B; Fleury-Souverain S; Beck A; Veuthey JL; Guillarme D; Fekete S
    J Pharm Biomed Anal; 2018 Jan; 147():493-505. PubMed ID: 28688616
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Determination of drug-to-antibody ratio of antibody-drug conjugate in biological samples using microflow-liquid chromatography/high-resolution mass spectrometry.
    Inoue K; Mochizuki T; Kasamori N; Komori T
    Bioanalysis; 2022 Dec; 14(24):1533-1545. PubMed ID: 36825963
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Drug-to-antibody determination for an antibody-drug-conjugate utilizing cathepsin B digestion coupled with reversed-phase high-pressure liquid chromatography analysis.
    Adamo M; Sun G; Qiu D; Valente J; Lan W; Song H; Bolgar M; Katiyar A; Krishnamurthy G
    J Chromatogr A; 2017 Jan; 1481():44-52. PubMed ID: 28017567
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.