These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 38402224)

  • 1. The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironment.
    Hardaker EL; Sanseviero E; Karmokar A; Taylor D; Milo M; Michaloglou C; Hughes A; Mai M; King M; Solanki A; Magiera L; Miragaia R; Kar G; Standifer N; Surace M; Gill S; Peter A; Talbot S; Tohumeken S; Fryer H; Mostafa A; Mulgrew K; Lam C; Hoffmann S; Sutton D; Carnevalli L; Calero-Nieto FJ; Jones GN; Pierce AJ; Wilson Z; Campbell D; Nyoni L; Martins CP; Baker T; Serrano de Almeida G; Ramlaoui Z; Bidar A; Phillips B; Boland J; Iyer S; Barrett JC; Loembé AB; Fuchs SY; Duvvuri U; Lou PJ; Nance MA; Gomez Roca CA; Cadogan E; Critichlow SE; Fawell S; Cobbold M; Dean E; Valge-Archer V; Lau A; Gabrilovich DI; Barry ST
    Nat Commun; 2024 Feb; 15(1):1700. PubMed ID: 38402224
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Biomarker-directed targeted therapy plus durvalumab in advanced non-small-cell lung cancer: a phase 2 umbrella trial.
    Besse B; Pons-Tostivint E; Park K; Hartl S; Forde PM; Hochmair MJ; Awad MM; Thomas M; Goss G; Wheatley-Price P; Shepherd FA; Florescu M; Cheema P; Chu QSC; Kim SW; Morgensztern D; Johnson ML; Cousin S; Kim DW; Moskovitz MT; Vicente D; Aronson B; Hobson R; Ambrose HJ; Khosla S; Reddy A; Russell DL; Keddar MR; Conway JP; Barrett JC; Dean E; Kumar R; Dressman M; Jewsbury PJ; Iyer S; Barry ST; Cosaert J; Heymach JV
    Nat Med; 2024 Mar; 30(3):716-729. PubMed ID: 38351187
    [TBL] [Abstract][Full Text] [Related]  

  • 3. WEE1 inhibitor and ataxia telangiectasia and RAD3-related inhibitor trigger stimulator of interferon gene-dependent immune response and enhance tumor treatment efficacy through programmed death-ligand 1 blockade.
    Wu X; Kang X; Zhang X; Xie W; Su Y; Liu X; Guo L; Guo E; Li F; Hu D; Qin X; Fu Y; Peng W; Jia J; Wang C
    Cancer Sci; 2021 Nov; 112(11):4444-4456. PubMed ID: 34382294
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phase II study of ceralasertib (AZD6738) in combination with durvalumab in patients with advanced/metastatic melanoma who have failed prior anti-PD-1 therapy.
    Kim R; Kwon M; An M; Kim ST; Smith SA; Loembé AB; Mortimer PGS; Armenia J; Lukashchuk N; Shah N; Dean E; Park WY; Lee J
    Ann Oncol; 2022 Feb; 33(2):193-203. PubMed ID: 34710570
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Phase II study of ceralasertib (AZD6738) in combination with durvalumab in patients with advanced gastric cancer.
    Kwon M; Kim G; Kim R; Kim KT; Kim ST; Smith S; Mortimer PGS; Hong JY; Loembé AB; Irurzun-Arana I; Koulai L; Kim KM; Kang WK; Dean E; Park WY; Lee J
    J Immunother Cancer; 2022 Jul; 10(7):. PubMed ID: 35790315
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation.
    Dillon MT; Guevara J; Mohammed K; Patin EC; Smith SA; Dean E; Jones GN; Willis SE; Petrone M; Silva C; Thway K; Bunce C; Roxanis I; Nenclares P; Wilkins A; McLaughlin M; Jayme-Laiche A; Benafif S; Nintos G; Kwatra V; Grove L; Mansfield D; Proszek P; Martin P; Moore L; Swales KE; Banerji U; Saunders MP; Spicer J; Forster MD; Harrington KJ
    J Clin Invest; 2024 Jan; 134(2):. PubMed ID: 37934611
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PTEN Depletion Increases Radiosensitivity in Response to Ataxia Telangiectasia-Related-3 (ATR) Inhibition in Non-Small Cell Lung Cancer (NSCLC).
    Dunne VL; Ghita-Pettigrew M; Redmond KM; Small DM; Weldon S; Taggart CC; Prise KM; Hanna GG; Butterworth KT
    Int J Mol Sci; 2024 Jul; 25(14):. PubMed ID: 39063060
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study.
    Yap TA; Krebs MG; Postel-Vinay S; El-Khouiery A; Soria JC; Lopez J; Berges A; Cheung SYA; Irurzun-Arana I; Goldwin A; Felicetti B; Jones GN; Lau A; Frewer P; Pierce AJ; Clack G; Stephens C; Smith SA; Dean E; Hollingsworth SJ
    Clin Cancer Res; 2021 Oct; 27(19):5213-5224. PubMed ID: 34301752
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phase I Study of Ceralasertib (AZD6738), a Novel DNA Damage Repair Agent, in Combination with Weekly Paclitaxel in Refractory Cancer.
    Kim ST; Smith SA; Mortimer P; Loembé AB; Cho H; Kim KM; Smith C; Willis S; Irurzun-Arana I; Berges A; Hong JY; Park SH; Park JO; Park YS; Lim HY; Kang WK; Kozarewa I; Pierce AJ; Dean E; Lee J
    Clin Cancer Res; 2021 Sep; 27(17):4700-4709. PubMed ID: 33975862
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ATR inhibitor AZD6738 enhances the antitumor activity of radiotherapy and immune checkpoint inhibitors by potentiating the tumor immune microenvironment in hepatocellular carcinoma.
    Sheng H; Huang Y; Xiao Y; Zhu Z; Shen M; Zhou P; Guo Z; Wang J; Wang H; Dai W; Zhang W; Sun J; Cao C
    J Immunother Cancer; 2020 May; 8(1):. PubMed ID: 32461345
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATR Inhibitor AZD6738 (Ceralasertib) Exerts Antitumor Activity as a Monotherapy and in Combination with Chemotherapy and the PARP Inhibitor Olaparib.
    Wilson Z; Odedra R; Wallez Y; Wijnhoven PWG; Hughes AM; Gerrard J; Jones GN; Bargh-Dawson H; Brown E; Young LA; O'Connor MJ; Lau A
    Cancer Res; 2022 Mar; 82(6):1140-1152. PubMed ID: 35078817
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ceralasertib-Mediated ATR Inhibition Combined With Olaparib in Advanced Cancers Harboring DNA Damage Response and Repair Alterations (Olaparib Combinations).
    Mahdi H; Hafez N; Doroshow D; Sohal D; Keedy V; Do KT; LoRusso P; Jürgensmeier J; Avedissian M; Sklar J; Glover C; Felicetti B; Dean E; Mortimer P; Shapiro GI; Eder JP
    JCO Precis Oncol; 2021; 5():. PubMed ID: 34527850
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combination ATR and PARP Inhibitor (CAPRI): A phase 2 study of ceralasertib plus olaparib in patients with recurrent, platinum-resistant epithelial ovarian cancer.
    Shah PD; Wethington SL; Pagan C; Latif N; Tanyi J; Martin LP; Morgan M; Burger RA; Haggerty A; Zarrin H; Rodriguez D; Domchek S; Drapkin R; Shih IM; Smith SA; Dean E; Gaillard S; Armstrong D; Torigian DA; Hwang WT; Giuntoli R; Simpkins F
    Gynecol Oncol; 2021 Nov; 163(2):246-253. PubMed ID: 34620496
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ATARI trial: ATR inhibitor in combination with olaparib in gynecological cancers with ARID1A loss or no loss (ENGOT/GYN1/NCRI).
    Banerjee S; Stewart J; Porta N; Toms C; Leary A; Lheureux S; Khalique S; Tai J; Attygalle A; Vroobel K; Lord CJ; Natrajan R; Bliss J
    Int J Gynecol Cancer; 2021 Nov; 31(11):1471-1475. PubMed ID: 34518240
    [TBL] [Abstract][Full Text] [Related]  

  • 15. ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation.
    Vendetti FP; Karukonda P; Clump DA; Teo T; Lalonde R; Nugent K; Ballew M; Kiesel BF; Beumer JH; Sarkar SN; Conrads TP; O'Connor MJ; Ferris RL; Tran PT; Delgoffe GM; Bakkenist CJ
    J Clin Invest; 2018 Aug; 128(9):3926-3940. PubMed ID: 29952768
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biomarker-driven phase 2 umbrella trial: Clinical efficacy of olaparib monotherapy and combination with ceralasertib (AZD6738) in small cell lung cancer.
    Park S; Kim YJ; Min YJ; Mortimer PGS; Kim HJ; Smith SA; Dean E; Jung HA; Sun JM; Park WY; Ahn JS; Ahn MJ; Lee SH; Park K
    Cancer; 2024 Feb; 130(4):541-552. PubMed ID: 37843249
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DUETTE: a phase II randomized, multicenter study to investigate the efficacy and tolerability of a second maintenance treatment in patients with platinum-sensitive relapsed epithelial ovarian cancer, who have previously received poly(ADP-ribose) polymerase (PARP) inhibitor maintenance treatment.
    McMullen M; Karakasis K; Loembe B; Dean E; Parr G; Oza AM
    Int J Gynecol Cancer; 2020 Nov; 30(11):1824-1828. PubMed ID: 32878963
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dose-dependent bioavailability and tissue distribution of the ATR inhibitor AZD6738 (ceralasertib) in mice.
    Kiesel BF; Guo J; Parise RA; Venkataramanan R; Clump DA; Bakkenist CJ; Beumer JH
    Cancer Chemother Pharmacol; 2022 Feb; 89(2):231-242. PubMed ID: 35066692
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CD4
    Xiao M; Xie L; Cao G; Lei S; Wang P; Wei Z; Luo Y; Fang J; Yang X; Huang Q; Xu L; Guo J; Wen S; Wang Z; Wu Q; Tang J; Wang L; Chen X; Chen C; Zhang Y; Yao W; Ye J; He R; Huang J; Ye L
    J Immunother Cancer; 2022 May; 10(5):. PubMed ID: 35580929
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Macitentan improves antitumor immune responses by inhibiting the secretion of tumor-derived extracellular vesicle PD-L1.
    Lee CH; Bae JH; Choe EJ; Park JM; Park SS; Cho HJ; Song BJ; Baek MC
    Theranostics; 2022; 12(5):1971-1987. PubMed ID: 35265193
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.