161 related articles for article (PubMed ID: 38408512)
1. Exploration of bromodomain ligand-linker conjugation sites for efficient CBP/p300 heterobifunctional degrader activity.
Kumar Tiwari P; Reddy Doda S; Vannam R; Hudlikar M; Harrison DA; Ojeda S; Rai S; Koglin AS; Nguyen Gilbert A; Ott CJ
Bioorg Med Chem Lett; 2024 Apr; 102():129676. PubMed ID: 38408512
[TBL] [Abstract][Full Text] [Related]
2. A beginner's guide to current synthetic linker strategies towards VHL-recruiting PROTACs.
Zografou-Barredo NA; Hallatt AJ; Goujon-Ricci J; Cano C
Bioorg Med Chem; 2023 Jun; 88-89():117334. PubMed ID: 37224698
[TBL] [Abstract][Full Text] [Related]
3. Kinetic Detection of E3:PROTAC:Target Ternary Complexes Using NanoBRET Technology in Live Cells.
Mahan SD; Riching KM; Urh M; Daniels DL
Methods Mol Biol; 2021; 2365():151-171. PubMed ID: 34432243
[TBL] [Abstract][Full Text] [Related]
4. Identification of ligand linkage vectors for the development of p300/CBP degraders.
Brownsey DK; Rowley BC; Gorobets E; Mihara K; Maity R; Papatzimas JW; Gelfand BS; Hollenberg MD; Bahlis NJ; Derksen DJ
RSC Med Chem; 2022 Jun; 13(6):726-730. PubMed ID: 35814928
[TBL] [Abstract][Full Text] [Related]
5. E3 Ligase Ligands in Successful PROTACs: An Overview of Syntheses and Linker Attachment Points.
Bricelj A; Steinebach C; Kuchta R; Gütschow M; Sosič I
Front Chem; 2021; 9():707317. PubMed ID: 34291038
[TBL] [Abstract][Full Text] [Related]
6. E3 ligase ligand chemistries: from building blocks to protein degraders.
Sosič I; Bricelj A; Steinebach C
Chem Soc Rev; 2022 May; 51(9):3487-3534. PubMed ID: 35393989
[TBL] [Abstract][Full Text] [Related]
7. SPR-Measured Dissociation Kinetics of PROTAC Ternary Complexes Influence Target Degradation Rate.
Roy MJ; Winkler S; Hughes SJ; Whitworth C; Galant M; Farnaby W; Rumpel K; Ciulli A
ACS Chem Biol; 2019 Mar; 14(3):361-368. PubMed ID: 30721025
[TBL] [Abstract][Full Text] [Related]
8. Efficient, multi-hundred-gram scale access to E3 ubiquitin ligase ligands for degrader development.
Cooper MS; Norley MC; Armitage S; Cresser-Brown JO; Edmonds AK; Goggins S; Hopewell JP; Karadogan B; Knights KA; Nash TJ; Oakes CS; O'Neill WJ; Pridmore SJ; Maple HJ; Marsh GP
Org Biomol Chem; 2023 Oct; 21(41):8344-8352. PubMed ID: 37800999
[TBL] [Abstract][Full Text] [Related]
9. Discovery and Characterization of Active CBP/EP300 Degraders Targeting the HAT Domain.
Cheng-Sánchez I; Gosselé KA; Palaferri L; Kirillova MS; Nevado C
ACS Med Chem Lett; 2024 Mar; 15(3):355-361. PubMed ID: 38505842
[TBL] [Abstract][Full Text] [Related]
10. Rationalizing PROTAC-Mediated Ternary Complex Formation Using Rosetta.
Bai N; Miller SA; Andrianov GV; Yates M; Kirubakaran P; Karanicolas J
J Chem Inf Model; 2021 Mar; 61(3):1368-1382. PubMed ID: 33625214
[TBL] [Abstract][Full Text] [Related]
11. Modeling the CRL4A ligase complex to predict target protein ubiquitination induced by cereblon-recruiting PROTACs.
Bai N; Riching KM; Makaju A; Wu H; Acker TM; Ou SC; Zhang Y; Shen X; Bulloch DN; Rui H; Gibson BW; Daniels DL; Urh M; Rock BM; Humphreys SC
J Biol Chem; 2022 Apr; 298(4):101653. PubMed ID: 35101445
[TBL] [Abstract][Full Text] [Related]
12. E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones.
Ishida T; Ciulli A
SLAS Discov; 2021 Apr; 26(4):484-502. PubMed ID: 33143537
[TBL] [Abstract][Full Text] [Related]
13. Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity.
Imaide S; Riching KM; Makukhin N; Vetma V; Whitworth C; Hughes SJ; Trainor N; Mahan SD; Murphy N; Cowan AD; Chan KH; Craigon C; Testa A; Maniaci C; Urh M; Daniels DL; Ciulli A
Nat Chem Biol; 2021 Nov; 17(11):1157-1167. PubMed ID: 34675414
[TBL] [Abstract][Full Text] [Related]
14. Targeted degradation of the enhancer lysine acetyltransferases CBP and p300.
Vannam R; Sayilgan J; Ojeda S; Karakyriakou B; Hu E; Kreuzer J; Morris R; Herrera Lopez XI; Rai S; Haas W; Lawrence M; Ott CJ
Cell Chem Biol; 2021 Apr; 28(4):503-514.e12. PubMed ID: 33400925
[TBL] [Abstract][Full Text] [Related]
15. Optimization of PROTAC Ternary Complex Using DNA Encoded Library Approach.
Chen Q; Liu C; Wang W; Meng X; Cheng X; Li X; Cai L; Luo L; He X; Qu H; Luo J; Wei H; Gao S; Liu G; Wan J; Israel DI; Li J; Dou D
ACS Chem Biol; 2023 Jan; 18(1):25-33. PubMed ID: 36606710
[TBL] [Abstract][Full Text] [Related]
16. Evaluating Ligands for Ubiquitin Ligases Using Affinity Beads.
Dobrodziej J; Dong H; Zimmermann K; Hickey CM
Methods Mol Biol; 2021; 2365():59-75. PubMed ID: 34432239
[TBL] [Abstract][Full Text] [Related]
17. Discovery of Novel PROTAC Degraders of p300/CBP as Potential Therapeutics for Hepatocellular Carcinoma.
Chang Q; Li J; Deng Y; Zhou R; Wang B; Wang Y; Zhang M; Huang X; Li Y
J Med Chem; 2024 Feb; 67(4):2466-2486. PubMed ID: 38316017
[TBL] [Abstract][Full Text] [Related]
18. Development of versatile solid-phase methods for syntheses of PROTACs with diverse E3 ligands.
Xu H; Kurohara T; Ohoka N; Tsuji G; Inoue T; Naito M; Demizu Y
Bioorg Med Chem; 2023 May; 86():117293. PubMed ID: 37126968
[TBL] [Abstract][Full Text] [Related]
19. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation.
Wurz RP; Dellamaggiore K; Dou H; Javier N; Lo MC; McCarter JD; Mohl D; Sastri C; Lipford JR; Cee VJ
J Med Chem; 2018 Jan; 61(2):453-461. PubMed ID: 28378579
[TBL] [Abstract][Full Text] [Related]
20. Structural basis of PROTAC cooperative recognition for selective protein degradation.
Gadd MS; Testa A; Lucas X; Chan KH; Chen W; Lamont DJ; Zengerle M; Ciulli A
Nat Chem Biol; 2017 May; 13(5):514-521. PubMed ID: 28288108
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]