131 related articles for article (PubMed ID: 38412690)
1. Computational screening of potential anti-inflammatory leads from Jeevaneeya Rasayana plants targeting COX-2 and 5- LOX by molecular docking and dynamic simulation approaches.
Hemavathi KN; Skariyachan S; Raju R; Keshava Prasad TS; Abhinand CS
Comput Biol Med; 2024 Mar; 171():108164. PubMed ID: 38412690
[TBL] [Abstract][Full Text] [Related]
2. 'Mechanistic insights into 5-lipoxygenase inhibition by active principles derived from essential oils of Curcuma species: Molecular docking, ADMET analysis and molecular dynamic simulation study.
Gadnayak A; Dehury B; Nayak A; Jena S; Sahoo A; Panda PC; Ray A; Nayak S
PLoS One; 2022; 17(7):e0271956. PubMed ID: 35867724
[TBL] [Abstract][Full Text] [Related]
3. Precise cuts for tailoring chromene-phenyl COX inhibitors with Ligand Designer.
Vo HHN; Phung THT; Chung KL; Vu TY
J Mol Graph Model; 2024 Jun; 129():108747. PubMed ID: 38447296
[TBL] [Abstract][Full Text] [Related]
4. Dual synergistic inhibition of COX and LOX by potential chemicals from Indian daily spices investigated through detailed computational studies.
Rudrapal M; Eltayeb WA; Rakshit G; El-Arabey AA; Khan J; Aldosari SM; Alshehri B; Abdalla M
Sci Rep; 2023 May; 13(1):8656. PubMed ID: 37244921
[TBL] [Abstract][Full Text] [Related]
5. Screening of potent inhibitor from
Sarmah P; Konwar P; Saikia J; Borah T; Verma JS; Banik D
J Biomol Struct Dyn; 2023 Oct; ():1-15. PubMed ID: 37885259
[TBL] [Abstract][Full Text] [Related]
6. Tailored quinoline hybrids as promising COX-2/15-LOX dual inhibitors endowed with diverse safety profile: Design, synthesis, SAR, and histopathological study.
Hegazy ME; Taher ES; Ghiaty AH; Bayoumi AH
Bioorg Chem; 2024 Apr; 145():107244. PubMed ID: 38428284
[TBL] [Abstract][Full Text] [Related]
7. Characterization of spirostanol glycosides and furostanol glycosides from anemarrhenae rhizoma as dual targeted inhibitors of 5-lipoxygenase and Cyclooxygenase-2 by employing a combination of affinity ultrafiltration and HPLC/MS.
Xie L; Lee DY; Shang Y; Cao X; Wang S; Liao J; Zhang T; Dai R
Phytomedicine; 2020 Oct; 77():153284. PubMed ID: 32707371
[TBL] [Abstract][Full Text] [Related]
8. Synthetically-tailored and nature-derived dual COX-2/5-LOX inhibitors: Structural aspects and SAR.
Meshram MA; Bhise UO; Makhal PN; Kaki VR
Eur J Med Chem; 2021 Dec; 225():113804. PubMed ID: 34479036
[TBL] [Abstract][Full Text] [Related]
9. The bioactive alkaloids identified from Cortex Phellodendri ameliorate benign prostatic hyperplasia via LOX-5/COX-2 pathways.
Wang S; Lee DY; Shang Y; Liao J; Cao X; Xie L; Zhang T; Liu J; Dai R
Phytomedicine; 2021 Dec; 93():153813. PubMed ID: 34735909
[TBL] [Abstract][Full Text] [Related]
10. Anti-inflammatory and antioxidant effects of Jeevaneeya Rasayana: an ayurvedic polyherbal formulation on acute and chronic models of inflammation.
Shyni GL; Ratheesh M; Sindhu G; Helen A
Immunopharmacol Immunotoxicol; 2010 Dec; 32(4):569-75. PubMed ID: 20136559
[TBL] [Abstract][Full Text] [Related]
11. Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids.
Abdu-Allah HHM; Abdelmoez AAB; Tarazi H; El-Shorbagi AA; El-Awady R
Bioorg Chem; 2020 Jan; 94():103378. PubMed ID: 31677858
[TBL] [Abstract][Full Text] [Related]
12. Dual acting anti-inflammatory drugs.
Leone S; Ottani A; Bertolini A
Curr Top Med Chem; 2007; 7(3):265-75. PubMed ID: 17305569
[TBL] [Abstract][Full Text] [Related]
13. Essential structural profile of a dual functional inhibitor against cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX): molecular docking and 3D-QSAR analyses on DHDMBF analogues.
Zheng M; Zhang Z; Zhu W; Liu H; Luo X; Chen K; Jiang H
Bioorg Med Chem; 2006 May; 14(10):3428-37. PubMed ID: 16458008
[TBL] [Abstract][Full Text] [Related]
14. Mollusc-Derived Brominated Indoles for the Selective Inhibition of Cyclooxygenase: A Computational Expedition.
Rahman MM; Junaid M; Hosen SMZ; Mostafa M; Liu L; Benkendorff K
Molecules; 2021 Oct; 26(21):. PubMed ID: 34770946
[TBL] [Abstract][Full Text] [Related]
15. Development of Novel Pyrrole Derivatives and Their Cinnamic Hybrids as Dual COX-2/LOX Inhibitors.
Noti V; Pontiki E; Hadjipavlou-Litina D
Molecules; 2023 Dec; 28(24):. PubMed ID: 38138448
[TBL] [Abstract][Full Text] [Related]
16. Lipoxygenase directed anti-inflammatory and anti-cancerous secondary metabolites: ADMET-based screening, molecular docking and dynamics simulation.
Singh S; Awasthi M; Pandey VP; Dwivedi UN
J Biomol Struct Dyn; 2017 Feb; 35(3):657-668. PubMed ID: 26942689
[TBL] [Abstract][Full Text] [Related]
17. Virtual Dual inhibition of COX-2 / 5-LOX enzymes based on binding properties of alpha-amyrins, the anti-inflammatory compound as a promising anti-cancer drug.
Ranjbar MM; Assadolahi V; Yazdani M; Nikaein D; Rashidieh B
EXCLI J; 2016; 15():238-45. PubMed ID: 27231478
[TBL] [Abstract][Full Text] [Related]
18. Exploration of binding site pattern in arachidonic acid metabolizing enzymes, Cyclooxygenases and Lipoxygenases.
Reddy KK; Vidya Rajan VK; Gupta A; Aparoy P; Reddanna P
BMC Res Notes; 2015 Apr; 8():152. PubMed ID: 25886468
[TBL] [Abstract][Full Text] [Related]
19. Celastrol modulates inflammation through inhibition of the catalytic activity of mediators of arachidonic acid pathway: Secretory phospholipase A
Joshi V; Venkatesha SH; Ramakrishnan C; Nanjaraj Urs AN; Hiremath V; Moudgil KD; Velmurugan D; Vishwanath BS
Pharmacol Res; 2016 Nov; 113(Pt A):265-275. PubMed ID: 27597642
[TBL] [Abstract][Full Text] [Related]
20. Docking Studies and Molecular Dynamics Simulation of
Yeni Y; Supandi S; Dwita LP; Suswandari S; Shaharun MS; Sambudi NS
J Pharm Bioallied Sci; 2020 Nov; 12(Suppl 2):S836-S840. PubMed ID: 33828386
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]