BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 38412690)

  • 1. Computational screening of potential anti-inflammatory leads from Jeevaneeya Rasayana plants targeting COX-2 and 5- LOX by molecular docking and dynamic simulation approaches.
    Hemavathi KN; Skariyachan S; Raju R; Keshava Prasad TS; Abhinand CS
    Comput Biol Med; 2024 Mar; 171():108164. PubMed ID: 38412690
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of spirostanol glycosides and furostanol glycosides from anemarrhenae rhizoma as dual targeted inhibitors of 5-lipoxygenase and Cyclooxygenase-2 by employing a combination of affinity ultrafiltration and HPLC/MS.
    Xie L; Lee DY; Shang Y; Cao X; Wang S; Liao J; Zhang T; Dai R
    Phytomedicine; 2020 Oct; 77():153284. PubMed ID: 32707371
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Further insight into the dual COX-2 and 15-LOX anti-inflammatory activity of 1,3,4-thiadiazole-thiazolidinone hybrids: The contribution of the substituents at 5th positions is size dependent.
    Omar YM; Abdel-Moty SG; Abdu-Allah HHM
    Bioorg Chem; 2020 Apr; 97():103657. PubMed ID: 32086052
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, biological evaluation and docking study of 1,3,4-thiadiazole-thiazolidinone hybrids as anti-inflammatory agents with dual inhibition of COX-2 and 15-LOX.
    Omar YM; Abdu-Allah HHM; Abdel-Moty SG
    Bioorg Chem; 2018 Oct; 80():461-471. PubMed ID: 29986191
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dual synergistic inhibition of COX and LOX by potential chemicals from Indian daily spices investigated through detailed computational studies.
    Rudrapal M; Eltayeb WA; Rakshit G; El-Arabey AA; Khan J; Aldosari SM; Alshehri B; Abdalla M
    Sci Rep; 2023 May; 13(1):8656. PubMed ID: 37244921
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthetically-tailored and nature-derived dual COX-2/5-LOX inhibitors: Structural aspects and SAR.
    Meshram MA; Bhise UO; Makhal PN; Kaki VR
    Eur J Med Chem; 2021 Dec; 225():113804. PubMed ID: 34479036
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition.
    Ghanim AM; Rezq S; Ibrahim TS; Romero DG; Kothayer H
    Eur J Med Chem; 2021 Jul; 219():113457. PubMed ID: 33892270
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of isoxazolo[4,5-d]pyridazin-4-(5H)-one analogues as potent anti-inflammatory agents.
    Özadalı K; Özkanlı F; Jain S; Rao PP; Velázquez-Martínez CA
    Bioorg Med Chem; 2012 May; 20(9):2912-22. PubMed ID: 22475926
    [TBL] [Abstract][Full Text] [Related]  

  • 9. New Substituted 5-Benzylideno-2-Adamantylthiazol[3,2-b][1,2,4]Triazol-6(5
    Tratrat C; Haroun M; Paparisva A; Kamoutsis C; Petrou A; Gavalas A; Eleftheriou P; Geronikaki A; Venugopala KN; Kochkar H; Nair AB
    Molecules; 2021 Jan; 26(3):. PubMed ID: 33513963
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Celastrol modulates inflammation through inhibition of the catalytic activity of mediators of arachidonic acid pathway: Secretory phospholipase A
    Joshi V; Venkatesha SH; Ramakrishnan C; Nanjaraj Urs AN; Hiremath V; Moudgil KD; Velmurugan D; Vishwanath BS
    Pharmacol Res; 2016 Nov; 113(Pt A):265-275. PubMed ID: 27597642
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Evaluation of in vitro and in silico anti-inflammatory potential of some selected medicinal plants of Bangladesh against cyclooxygenase-II enzyme.
    Islam MA; Zilani MNH; Biswas P; Khan DA; Rahman MH; Nahid R; Nahar N; Samad A; Ahammad F; Hasan MN
    J Ethnopharmacol; 2022 Mar; 285():114900. PubMed ID: 34896569
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conjugation of 4-aminosalicylate with thiazolinones afforded non-cytotoxic potent in vitro and in vivo anti-inflammatory hybrids.
    Abdu-Allah HHM; Abdelmoez AAB; Tarazi H; El-Shorbagi AA; El-Awady R
    Bioorg Chem; 2020 Jan; 94():103378. PubMed ID: 31677858
    [TBL] [Abstract][Full Text] [Related]  

  • 13. An Insilico evaluation of phytocompounds from Albizia amara and Phyla nodiflora as cyclooxygenase-2 enzyme inhibitors.
    Loganathan Y; Jain M; Thiyagarajan S; Shanmuganathan S; Mariappan SK; Kizhakedathil MPJ; Saravanakumar T
    Daru; 2021 Dec; 29(2):311-320. PubMed ID: 34415547
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of key enzymes in the inflammatory pathway by hybrid molecules of terpenes and synthetic drugs: In vitro and in silico studies.
    Theoduloz C; Alzate-Morales J; Jiménez-Aspee F; Isla MI; Alberto MR; Pertino MW; Schmeda-Hirschmann G
    Chem Biol Drug Des; 2019 Mar; 93(3):290-299. PubMed ID: 30294891
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 'Mechanistic insights into 5-lipoxygenase inhibition by active principles derived from essential oils of Curcuma species: Molecular docking, ADMET analysis and molecular dynamic simulation study.
    Gadnayak A; Dehury B; Nayak A; Jena S; Sahoo A; Panda PC; Ray A; Nayak S
    PLoS One; 2022; 17(7):e0271956. PubMed ID: 35867724
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 3,5-Disubstituted Isoxazole Derivatives: Potential Inhibitors of Inflammation and Cancer.
    Rakesh KS; Jagadish S; Balaji KS; Zameer F; Swaroop TR; Mohan CD; Jayarama S; Rangappa KS
    Inflammation; 2016 Feb; 39(1):269-280. PubMed ID: 26363638
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Essential structural profile of a dual functional inhibitor against cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX): molecular docking and 3D-QSAR analyses on DHDMBF analogues.
    Zheng M; Zhang Z; Zhu W; Liu H; Luo X; Chen K; Jiang H
    Bioorg Med Chem; 2006 May; 14(10):3428-37. PubMed ID: 16458008
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel class of benzimidazole-thiazole hybrids: The privileged scaffolds of potent anti-inflammatory activity with dual inhibition of cyclooxygenase and 15-lipoxygenase enzymes.
    Maghraby MT; Abou-Ghadir OMF; Abdel-Moty SG; Ali AY; Salem OIA
    Bioorg Med Chem; 2020 Apr; 28(7):115403. PubMed ID: 32127262
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Development of Novel Pyrrole Derivatives and Their Cinnamic Hybrids as Dual COX-2/LOX Inhibitors.
    Noti V; Pontiki E; Hadjipavlou-Litina D
    Molecules; 2023 Dec; 28(24):. PubMed ID: 38138448
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanistic evaluation of a novel cyclohexenone derivative's functionality against nociception and inflammation: An in-vitro, in-vivo and in-silico approach.
    Khan J; Ali G; Rashid U; Khan R; Jan MS; Ullah R; Ahmad S; Abbasi SW; Khan Khalil AA; Sewell RE
    Eur J Pharmacol; 2021 Jul; 902():174091. PubMed ID: 33865830
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.