BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 38413232)

  • 1. Human Motor Neurons Elicit Pathological Hallmarks of ALS and Reveal Potential Biomarkers of the Disease in Response to Prolonged IFNγ Exposure.
    Chun C; Lee JH; Bothwell M; Nghiem P; Smith AST; Mack DL
    J Neurosci; 2024 Apr; 44(16):. PubMed ID: 38413232
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis.
    Smethurst P; Risse E; Tyzack GE; Mitchell JS; Taha DM; Chen YR; Newcombe J; Collinge J; Sidle K; Patani R
    Brain; 2020 Feb; 143(2):430-440. PubMed ID: 32040555
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Neuronal STING activation in amyotrophic lateral sclerosis and frontotemporal dementia.
    Marques C; Held A; Dorfman K; Sung J; Song C; Kavuturu AS; Aguilar C; Russo T; Oakley DH; Albers MW; Hyman BT; Petrucelli L; Lagier-Tourenne C; Wainger BJ
    Acta Neuropathol; 2024 Mar; 147(1):56. PubMed ID: 38478117
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits.
    Hu Y; Hruscha A; Pan C; Schifferer M; Schmidt MK; Nuscher B; Giera M; Kostidis S; Burhan Ö; van Bebber F; Edbauer D; Arzberger T; Haass C; Schmid B
    Mol Neurodegener; 2024 Jun; 19(1):50. PubMed ID: 38902734
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pathological Modification of TDP-43 in Amyotrophic Lateral Sclerosis with SOD1 Mutations.
    Jeon GS; Shim YM; Lee DY; Kim JS; Kang M; Ahn SH; Shin JY; Geum D; Hong YH; Sung JJ
    Mol Neurobiol; 2019 Mar; 56(3):2007-2021. PubMed ID: 29982983
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration.
    Gomez-Deza J; Lee YB; Troakes C; Nolan M; Al-Sarraj S; Gallo JM; Shaw CE
    Acta Neuropathol Commun; 2015 Jun; 3():38. PubMed ID: 26108573
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43.
    Walker AK; Spiller KJ; Ge G; Zheng A; Xu Y; Zhou M; Tripathy K; Kwong LK; Trojanowski JQ; Lee VM
    Acta Neuropathol; 2015 Nov; 130(5):643-60. PubMed ID: 26197969
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Co-deposition of SOD1, TDP-43 and p62 proteinopathies in ALS: evidence for multifaceted pathways underlying neurodegeneration.
    Trist BG; Fifita JA; Hogan A; Grima N; Smith B; Troakes C; Vance C; Shaw C; Al-Sarraj S; Blair IP; Double KL
    Acta Neuropathol Commun; 2022 Aug; 10(1):122. PubMed ID: 36008843
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS.
    Mitchell JC; Constable R; So E; Vance C; Scotter E; Glover L; Hortobagyi T; Arnold ES; Ling SC; McAlonis M; Da Cruz S; Polymenidou M; Tessarolo L; Cleveland DW; Shaw CE
    Acta Neuropathol Commun; 2015 Jun; 3():36. PubMed ID: 26108367
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Enhancing survival motor neuron expression extends lifespan and attenuates neurodegeneration in mutant TDP-43 mice.
    Perera ND; Sheean RK; Crouch PJ; White AR; Horne MK; Turner BJ
    Hum Mol Genet; 2016 Sep; 25(18):4080-4093. PubMed ID: 27466204
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stress-Specific Spatiotemporal Responses of RNA-Binding Proteins in Human Stem-Cell-Derived Motor Neurons.
    Harley J; Patani R
    Int J Mol Sci; 2020 Nov; 21(21):. PubMed ID: 33172210
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Modeling Protein Aggregation and the Heat Shock Response in ALS iPSC-Derived Motor Neurons.
    Seminary ER; Sison SL; Ebert AD
    Front Neurosci; 2018; 12():86. PubMed ID: 29515358
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TDP-43 in differential diagnosis of motor neuron disorders.
    Dickson DW; Josephs KA; Amador-Ortiz C
    Acta Neuropathol; 2007 Jul; 114(1):71-9. PubMed ID: 17569066
    [TBL] [Abstract][Full Text] [Related]  

  • 14. cAMP/PKA signaling regulates TDP-43 aggregation and mislocalization.
    Ho DM; Shaban M; Mahmood F; Ganguly P; Todeschini L; Van Vactor D; Artavanis-Tsakonas S
    Proc Natl Acad Sci U S A; 2024 Jun; 121(24):e2400732121. PubMed ID: 38838021
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MicroRNA-183-5p regulates TAR DNA-binding protein 43 neurotoxicity via SQSTM1/p62 in amyotrophic lateral sclerosis.
    Kim HC; Zhang Y; King PH; Lu L
    J Neurochem; 2023 Mar; 164(5):643-657. PubMed ID: 36527420
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Selective Motor Neuron Resistance and Recovery in a New Inducible Mouse Model of TDP-43 Proteinopathy.
    Spiller KJ; Cheung CJ; Restrepo CR; Kwong LK; Stieber AM; Trojanowski JQ; Lee VM
    J Neurosci; 2016 Jul; 36(29):7707-17. PubMed ID: 27445147
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations.
    Finelli MJ; Liu KX; Wu Y; Oliver PL; Davies KE
    Hum Mol Genet; 2015 Jun; 24(12):3529-44. PubMed ID: 25792726
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction.
    Gordon D; Dafinca R; Scaber J; Alegre-Abarrategui J; Farrimond L; Scott C; Biggs D; Kent L; Oliver PL; Davies B; Ansorge O; Wade-Martins R; Talbot K
    Neurobiol Dis; 2019 Jan; 121():148-162. PubMed ID: 30290270
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Motor neurons and glia exhibit specific individualized responses to TDP-43 expression in a Drosophila model of amyotrophic lateral sclerosis.
    Estes PS; Daniel SG; McCallum AP; Boehringer AV; Sukhina AS; Zwick RA; Zarnescu DC
    Dis Model Mech; 2013 May; 6(3):721-33. PubMed ID: 23471911
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Specific vulnerability of iPSC-derived motor neurons with TDP-43 gene mutation to oxidative stress.
    Onda-Ohto A; Hasegawa-Ogawa M; Matsuno H; Shiraishi T; Bono K; Hiraki H; Kanegae Y; Iguchi Y; Okano HJ
    Mol Brain; 2023 Jul; 16(1):62. PubMed ID: 37496071
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.