BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 38418456)

  • 21. The human papillomavirus E6 oncogene represses a cell adhesion pathway and disrupts focal adhesion through degradation of TAp63β upon transformation.
    Ben Khalifa Y; Teissier S; Tan MK; Phan QT; Daynac M; Wong WQ; Thierry F
    PLoS Pathog; 2011 Sep; 7(9):e1002256. PubMed ID: 21980285
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A Critical Role for p53 during the HPV16 Life Cycle.
    Fontan CT; James CD; Prabhakar AT; Bristol ML; Otoa R; Wang X; Karimi E; Rajagopalan P; Basu D; Morgan IM
    Microbiol Spectr; 2022 Jun; 10(3):e0068122. PubMed ID: 35608342
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Solution structure analysis of the HPV16 E6 oncoprotein reveals a self-association mechanism required for E6-mediated degradation of p53.
    Zanier K; ould M'hamed ould Sidi A; Boulade-Ladame C; Rybin V; Chappelle A; Atkinson A; Kieffer B; Travé G
    Structure; 2012 Apr; 20(4):604-17. PubMed ID: 22483108
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Human papillomavirus type 16 E6 induces self-ubiquitination of the E6AP ubiquitin-protein ligase.
    Kao WH; Beaudenon SL; Talis AL; Huibregtse JM; Howley PM
    J Virol; 2000 Jul; 74(14):6408-17. PubMed ID: 10864652
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Molecular modeling simulation studies reveal new potential inhibitors against HPV E6 protein.
    Ricci-López J; Vidal-Limon A; Zunñiga M; Jimènez VA; Alderete JB; Brizuela CA; Aguila S
    PLoS One; 2019; 14(3):e0213028. PubMed ID: 30875378
    [TBL] [Abstract][Full Text] [Related]  

  • 26. GRIM-19 disrupts E6/E6AP complex to rescue p53 and induce apoptosis in cervical cancers.
    Zhou Y; Wei Y; Zhu J; Wang Q; Bao L; Ma Y; Chen Y; Feng D; Zhang A; Sun J; Nallar SC; Shen K; Kalvakolanu DV; Xiao W; Ling B
    PLoS One; 2011; 6(7):e22065. PubMed ID: 21765936
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Quercetin induces G2 phase arrest and apoptosis with the activation of p53 in an E6 expression‑independent manner in HPV‑positive human cervical cancer‑derived cells.
    Clemente-Soto AF; Salas-Vidal E; Milan-Pacheco C; Sánchez-Carranza JN; Peralta-Zaragoza O; González-Maya L
    Mol Med Rep; 2019 Mar; 19(3):2097-2106. PubMed ID: 30664221
    [TBL] [Abstract][Full Text] [Related]  

  • 28. HPV16 E6 confers p53-dependent and p53-independent phenotypes in the epidermis of mice deficient for E6AP.
    Shai A; Nguyen ML; Wagstaff J; Jiang YH; Lambert PF
    Oncogene; 2007 May; 26(23):3321-8. PubMed ID: 17130828
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.
    Poirson J; Biquand E; Straub ML; Cassonnet P; Nominé Y; Jones L; van der Werf S; Travé G; Zanier K; Jacob Y; Demeret C; Masson M
    FEBS J; 2017 Oct; 284(19):3171-3201. PubMed ID: 28786561
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Association strength of E6 to E6AP/p53 complex correlates with HPV-mediated oncogenesis risk.
    Ferraz MVF; Viana IFT; Coêlho DF; da Cruz CHB; de Arruda Lima M; de Luna Aragão MA; Lins RD
    Biopolymers; 2022 Oct; 113(10):e23524. PubMed ID: 36281776
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Cellular steady-state levels of "high risk" but not "low risk" human papillomavirus (HPV) E6 proteins are increased by inhibition of proteasome-dependent degradation independent of their p53- and E6AP-binding capabilities.
    Kehmeier E; Rühl H; Voland B; Stöppler MC; Androphy E; Stöppler H
    Virology; 2002 Jul; 299(1):72-87. PubMed ID: 12167343
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Surface plasmon resonance imaging protein arrays for analysis of triple protein interactions of HPV, E6, E6AP, and p53.
    Ro HS; Koh BH; Jung SO; Park HK; Shin YB; Kim MG; Chung BH
    Proteomics; 2006 Apr; 6(7):2108-11. PubMed ID: 16493710
    [TBL] [Abstract][Full Text] [Related]  

  • 33. E6 proteins from high-risk HPV, low-risk HPV, and animal papillomaviruses activate the Wnt/β-catenin pathway through E6AP-dependent degradation of NHERF1.
    Drews CM; Case S; Vande Pol SB
    PLoS Pathog; 2019 Apr; 15(4):e1007575. PubMed ID: 31002735
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Identification and characterization of small molecule human papillomavirus E6 inhibitors.
    Malecka KA; Fera D; Schultz DC; Hodawadekar S; Reichman M; Donover PS; Murphy ME; Marmorstein R
    ACS Chem Biol; 2014 Jul; 9(7):1603-12. PubMed ID: 24854633
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Structural dynamics of the E6AP/UBE3A-E6-p53 enzyme-substrate complex.
    Sailer C; Offensperger F; Julier A; Kammer KM; Walker-Gray R; Gold MG; Scheffner M; Stengel F
    Nat Commun; 2018 Oct; 9(1):4441. PubMed ID: 30361475
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Identification of E6AP-independent degradation targets of HPV E6.
    Vats A; Thatte J; Banks L
    J Gen Virol; 2019 Dec; 100(12):1674-1679. PubMed ID: 31609195
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The E6AP binding pocket of the HPV16 E6 oncoprotein provides a docking site for a small inhibitory peptide unrelated to E6AP, indicating druggability of E6.
    Zanier K; Stutz C; Kintscher S; Reinz E; Sehr P; Bulkescher J; Hoppe-Seyler K; Travé G; Hoppe-Seyler F
    PLoS One; 2014; 9(11):e112514. PubMed ID: 25383876
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A single-codon mutation converts HPV16 E6 oncoprotein into a potential tumor suppressor, which induces p53-dependent senescence of HPV-positive HeLa cervical cancer cells.
    Ristriani T; Fournane S; Orfanoudakis G; Travé G; Masson M
    Oncogene; 2009 Feb; 28(5):762-72. PubMed ID: 19015633
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Human Papillomavirus 16 Oncoprotein Expression Is Controlled by the Cellular Splicing Factor SRSF2 (SC35).
    McFarlane M; MacDonald AI; Stevenson A; Graham SV
    J Virol; 2015 May; 89(10):5276-87. PubMed ID: 25717103
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The role of E6AP in the regulation of p53 protein levels in human papillomavirus (HPV)-positive and HPV-negative cells.
    Talis AL; Huibregtse JM; Howley PM
    J Biol Chem; 1998 Mar; 273(11):6439-45. PubMed ID: 9497376
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.