BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 38442309)

  • 1. Acquired Multidrug Resistance in AML Is Caused by Low Apoptotic Priming in Relapsed Myeloblasts.
    Olesinski EA; Bhatia KS; Wang C; Pioso MS; Lin XX; Mamdouh AM; Ng SX; Sandhu V; Jasdanwala SS; Yilma B; Bohl S; Ryan JA; Malani D; Luskin MR; Kallioniemi O; Porkka K; Adamia S; Chng WJ; Osato M; Weinstock DM; Garcia JS; Letai A; Bhatt S
    Blood Cancer Discov; 2024 May; 5(3):180-201. PubMed ID: 38442309
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia.
    Bhatt S; Pioso MS; Olesinski EA; Yilma B; Ryan JA; Mashaka T; Leutz B; Adamia S; Zhu H; Kuang Y; Mogili A; Louissaint A; Bohl SR; Kim AS; Mehta AK; Sanghavi S; Wang Y; Morris E; Halilovic E; Paweletz CP; Weinstock DM; Garcia JS; Letai A
    Cancer Cell; 2020 Dec; 38(6):872-890.e6. PubMed ID: 33217342
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functionally identifiable apoptosis-insensitive subpopulations determine chemoresistance in acute myeloid leukemia.
    Bhola PD; Mar BG; Lindsley RC; Ryan JA; Hogdal LJ; Vo TT; DeAngelo DJ; Galinsky I; Ebert BL; Letai A
    J Clin Invest; 2016 Oct; 126(10):3827-3836. PubMed ID: 27599292
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetic biomarkers of drug resistance: A compass of prognosis and targeted therapy in acute myeloid leukemia.
    Long L; Assaraf YG; Lei ZN; Peng H; Yang L; Chen ZS; Ren S
    Drug Resist Updat; 2020 Sep; 52():100703. PubMed ID: 32599434
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Emodin and Its Combination with Cytarabine Induce Apoptosis in Resistant Acute Myeloid Leukemia Cells in Vitro and in Vivo.
    Chen Y; Gan D; Huang Q; Luo X; Lin D; Hu J
    Cell Physiol Biochem; 2018; 48(5):2061-2073. PubMed ID: 30099447
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dielectrophoretic Microfluidic Chip Enables Single-Cell Measurements for Multidrug Resistance in Heterogeneous Acute Myeloid Leukemia Patient Samples.
    Khamenehfar A; Gandhi MK; Chen Y; Hogge DE; Li PC
    Anal Chem; 2016 Jun; 88(11):5680-8. PubMed ID: 27149245
    [TBL] [Abstract][Full Text] [Related]  

  • 7. miR-181b increases drug sensitivity in acute myeloid leukemia via targeting HMGB1 and Mcl-1.
    Lu F; Zhang J; Ji M; Li P; Du Y; Wang H; Zang S; Ma D; Sun X; Ji C
    Int J Oncol; 2014 Jul; 45(1):383-92. PubMed ID: 24756163
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Deregulation of the mitochondrial apoptotic machinery and development of molecular targeted drugs in acute myeloid leukemia.
    Del Poeta G; Bruno A; Del Principe MI; Venditti A; Maurillo L; Buccisano F; Stasi R; Neri B; Luciano F; Siniscalchi A; de Fabritiis P; Amadori S
    Curr Cancer Drug Targets; 2008 May; 8(3):207-22. PubMed ID: 18473734
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Chemotherapy-Resistant Human Acute Myeloid Leukemia Cells Are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism.
    Farge T; Saland E; de Toni F; Aroua N; Hosseini M; Perry R; Bosc C; Sugita M; Stuani L; Fraisse M; Scotland S; Larrue C; Boutzen H; Féliu V; Nicolau-Travers ML; Cassant-Sourdy S; Broin N; David M; Serhan N; Sarry A; Tavitian S; Kaoma T; Vallar L; Iacovoni J; Linares LK; Montersino C; Castellano R; Griessinger E; Collette Y; Duchamp O; Barreira Y; Hirsch P; Palama T; Gales L; Delhommeau F; Garmy-Susini BH; Portais JC; Vergez F; Selak M; Danet-Desnoyers G; Carroll M; Récher C; Sarry JE
    Cancer Discov; 2017 Jul; 7(7):716-735. PubMed ID: 28416471
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Deregulation of mitochondrial ATPsyn-β in acute myeloid leukemia cells and with increased drug resistance.
    Xiao X; Yang J; Li R; Liu S; Xu Y; Zheng W; Yi Y; Luo Y; Gong F; Peng H; Pei M; Deng M; Zhang G
    PLoS One; 2013; 8(12):e83610. PubMed ID: 24391795
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reversal of acquired drug resistance in FLT3-mutated acute myeloid leukemia cells via distinct drug combination strategies.
    Zhang W; Gao C; Konopleva M; Chen Y; Jacamo RO; Borthakur G; Cortes JE; Ravandi F; Ramachandran A; Andreeff M
    Clin Cancer Res; 2014 May; 20(9):2363-74. PubMed ID: 24619500
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antineoplastic activity of ouabain and pyrithione zinc in acute myeloid leukemia.
    Tailler M; Senovilla L; Lainey E; Thépot S; Métivier D; Sébert M; Baud V; Billot K; Fenaux P; Galluzzi L; Boehrer S; Kroemer G; Kepp O
    Oncogene; 2012 Jul; 31(30):3536-46. PubMed ID: 22105358
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Increased mitochondrial apoptotic priming with targeted therapy predicts clinical response to re-induction chemotherapy.
    Garcia JS; Bhatt S; Fell G; Sperling AS; Burgess M; Keshishian H; Yilma B; Brunner A; Neuberg D; Carr SA; Ebert BL; Ballen K; Stone RM; DeAngelo DJ; Medeiros BC; Letai A
    Am J Hematol; 2020 Mar; 95(3):245-250. PubMed ID: 31804723
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML.
    Lindblad O; Cordero E; Puissant A; Macaulay L; Ramos A; Kabir NN; Sun J; Vallon-Christersson J; Haraldsson K; Hemann MT; Borg Å; Levander F; Stegmaier K; Pietras K; Rönnstrand L; Kazi JU
    Oncogene; 2016 Sep; 35(39):5119-31. PubMed ID: 26999641
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dynamic BH3 profiling method for rapid identification of active therapy in BH3 mimetics resistant xenograft mouse models.
    Olesinski EA; Bhatt S
    STAR Protoc; 2021 Jun; 2(2):100461. PubMed ID: 34027474
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Relative mitochondrial priming of myeloblasts and normal HSCs determines chemotherapeutic success in AML.
    Vo TT; Ryan J; Carrasco R; Neuberg D; Rossi DJ; Stone RM; Deangelo DJ; Frattini MG; Letai A
    Cell; 2012 Oct; 151(2):344-55. PubMed ID: 23063124
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Downregulation of microRNA let-7f mediated the Adriamycin resistance in leukemia cell line.
    Cao YX; Wen F; Luo ZY; Long XX; Luo C; Liao P; Li JJ
    J Cell Biochem; 2020 Oct; 121(10):4022-4033. PubMed ID: 31793054
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitophagy Promotes Resistance to BH3 Mimetics in Acute Myeloid Leukemia.
    Glytsou C; Chen X; Zacharioudakis E; Al-Santli W; Zhou H; Nadorp B; Lee S; Lasry A; Sun Z; Papaioannou D; Cammer M; Wang K; Zal T; Zal MA; Carter BZ; Ishizawa J; Tibes R; Tsirigos A; Andreeff M; Gavathiotis E; Aifantis I
    Cancer Discov; 2023 Jul; 13(7):1656-1677. PubMed ID: 37088914
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ABCG2 in Acute Myeloid Leukemia: Old and New Perspectives.
    Damiani D; Tiribelli M
    Int J Mol Sci; 2023 Apr; 24(8):. PubMed ID: 37108308
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthetic lethality of combined AT-101 with idarubicin in acute myeloid leukemia via blockade of DNA repair and activation of intrinsic apoptotic pathway.
    Yang Q; Chen K; Zhang L; Feng L; Fu G; Jiang S; Bi S; Lin C; Zhou Y; Zhao H; Chen XL; Fu G; Xu B
    Cancer Lett; 2019 Oct; 461():31-43. PubMed ID: 31301319
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.