These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

133 related articles for article (PubMed ID: 38447882)

  • 1. AurkA/TPX2 co-overexpression in nontransformed cells promotes genome instability through induction of chromosome mis-segregation and attenuation of the p53 signalling pathway.
    Naso FD; Polverino F; Cilluffo D; Latini L; Stagni V; Asteriti IA; Rosa A; Soddu S; Guarguaglini G
    Biochim Biophys Acta Mol Basis Dis; 2024 Apr; 1870(4):167116. PubMed ID: 38447882
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Contribution of AurkA/TPX2 Overexpression to Chromosomal Imbalances and Cancer.
    Polverino F; Mastrangelo A; Guarguaglini G
    Cells; 2024 Aug; 13(16):. PubMed ID: 39195284
    [TBL] [Abstract][Full Text] [Related]  

  • 3. AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation.
    Asteriti IA; Polverino F; Stagni V; Sterbini V; Ascanelli C; Naso FD; Mastrangelo A; Rosa A; Paiardini A; Lindon C; Guarguaglini G
    Life Sci Alliance; 2023 May; 6(5):. PubMed ID: 36797043
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The AURKA/TPX2 axis drives colon tumorigenesis cooperatively with MYC.
    Takahashi Y; Sheridan P; Niida A; Sawada G; Uchi R; Mizuno H; Kurashige J; Sugimachi K; Sasaki S; Shimada Y; Hase K; Kusunoki M; Kudo S; Watanabe M; Yamada K; Sugihara K; Yamamoto H; Suzuki A; Doki Y; Miyano S; Mori M; Mimori K
    Ann Oncol; 2015 May; 26(5):935-942. PubMed ID: 25632068
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Taxane-mediated radiosensitization derives from chromosomal missegregation on tripolar mitotic spindles orchestrated by AURKA and TPX2.
    Orth M; Unger K; Schoetz U; Belka C; Lauber K
    Oncogene; 2018 Jan; 37(1):52-62. PubMed ID: 28869599
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Bcl2l10, a new Tpx2 binding partner, is a master regulator of Aurora kinase A in mouse oocytes.
    Lee SY; Kim EY; Kim KH; Lee KA
    Cell Cycle; 2016 Dec; 15(23):3296-3305. PubMed ID: 27753540
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aurora A kinase and its activator TPX2 are potential therapeutic targets in KRAS-induced pancreatic cancer.
    Gomes-Filho SM; Dos Santos EO; Bertoldi ERM; Scalabrini LC; Heidrich V; Dazzani B; Levantini E; Reis EM; Bassères DS
    Cell Oncol (Dordr); 2020 Jun; 43(3):445-460. PubMed ID: 32193808
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tpx2 controls spindle integrity, genome stability, and tumor development.
    Aguirre-Portolés C; Bird AW; Hyman A; Cañamero M; Pérez de Castro I; Malumbres M
    Cancer Res; 2012 Mar; 72(6):1518-28. PubMed ID: 22266221
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells.
    van Gijn SE; Wierenga E; van den Tempel N; Kok YP; Heijink AM; Spierings DCJ; Foijer F; van Vugt MATM; Fehrmann RSN
    Oncogene; 2019 Feb; 38(6):852-867. PubMed ID: 30177840
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Aurora A phosphorylation of WD40-repeat protein 62 in mitotic spindle regulation.
    Lim NR; Yeap YY; Ang CS; Williamson NA; Bogoyevitch MA; Quinn LM; Ng DC
    Cell Cycle; 2016; 15(3):413-24. PubMed ID: 26713495
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2.
    Janeček M; Rossmann M; Sharma P; Emery A; Huggins DJ; Stockwell SR; Stokes JE; Tan YS; Almeida EG; Hardwick B; Narvaez AJ; Hyvönen M; Spring DR; McKenzie GJ; Venkitaraman AR
    Sci Rep; 2016 Jun; 6():28528. PubMed ID: 27339427
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2.
    Li L; Yang G; Ren C; Tanimoto R; Hirayama T; Wang J; Hawke D; Kim SM; Lee JS; Goltsov AA; Park S; Ittmann MM; Troncoso P; Thompson TC
    Mol Oncol; 2013 Jun; 7(3):484-96. PubMed ID: 23333597
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Unveiling Potential Targeted Therapeutic Opportunities for Co-Overexpressed Targeting Protein for Xklp2 and Aurora-A Kinase in Lung Adenocarcinoma.
    Mukherjee A; Yadav PH; Mukunthan KS
    Mol Biotechnol; 2024 Oct; 66(10):2792-2803. PubMed ID: 37768502
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of small molecule inhibitors of the Aurora-A/TPX2 complex.
    Asteriti IA; Daidone F; Colotti G; Rinaldo S; Lavia P; Guarguaglini G; Paiardini A
    Oncotarget; 2017 May; 8(19):32117-32133. PubMed ID: 28389630
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Spatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2.
    Chen H; Mohan P; Jiang J; Nemirovsky O; He D; Fleisch MC; Niederacher D; Pilarski LM; Lim CJ; Maxwell CA
    Cell Cycle; 2014; 13(14):2248-61. PubMed ID: 24875404
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit.
    Naso FD; Sterbini V; Crecca E; Asteriti IA; Russo AD; Giubettini M; Cundari E; Lindon C; Rosa A; Guarguaglini G
    Cells; 2020 Feb; 9(2):. PubMed ID: 32041138
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TPX2 deficiency leads to spindle abnormity and meiotic impairment in porcine oocytes.
    He Y; Peng L; Li J; Li Q; Chu Y; Lin Q; Rui R; Ju S
    Theriogenology; 2022 Jul; 187():164-172. PubMed ID: 35576634
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A.
    Bird AW; Hyman AA
    J Cell Biol; 2008 Jul; 182(2):289-300. PubMed ID: 18663142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TPX2 overexpression in medullary thyroid carcinoma mediates TT cell proliferation.
    Yang X; Liu G; Xiao H; Yu F; Xiang X; Lu Y; Li W; Liu X; Li S; Shi Y
    Pathol Oncol Res; 2014 Jul; 20(3):641-8. PubMed ID: 24488334
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The Aurora-A/TPX2 Axis Directs Spindle Orientation in Adherent Human Cells by Regulating NuMA and Microtubule Stability.
    Polverino F; Naso FD; Asteriti IA; Palmerini V; Singh D; Valente D; Bird AW; Rosa A; Mapelli M; Guarguaglini G
    Curr Biol; 2021 Feb; 31(3):658-667.e5. PubMed ID: 33275894
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.