These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 38450831)

  • 1. Genetic modifiers of cognitive decline in PSEN1 E280A Alzheimer's disease.
    Sepulveda-Falla D; Vélez JI; Acosta-Baena N; Baena A; Moreno S; Krasemann S; Lopera F; Mastronardi CA; Arcos-Burgos M
    Alzheimers Dement; 2024 Apr; 20(4):2873-2885. PubMed ID: 38450831
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.
    Ochalek A; Mihalik B; Avci HX; Chandrasekaran A; Téglási A; Bock I; Giudice ML; Táncos Z; Molnár K; László L; Nielsen JE; Holst B; Freude K; Hyttel P; Kobolák J; Dinnyés A
    Alzheimers Res Ther; 2017 Dec; 9(1):90. PubMed ID: 29191219
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cholinergic-like neurons carrying PSEN1 E280A mutation from familial Alzheimer's disease reveal intraneuronal sAPPβ fragments accumulation, hyperphosphorylation of TAU, oxidative stress, apoptosis and Ca2+ dysregulation: Therapeutic implications.
    Soto-Mercado V; Mendivil-Perez M; Velez-Pardo C; Lopera F; Jimenez-Del-Rio M
    PLoS One; 2020; 15(5):e0221669. PubMed ID: 32437347
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cognitive decline in patients with familial Alzheimer's disease associated with E280a presenilin-1 mutation: a longitudinal study.
    Rosselli MC; Ardila AC; Moreno SC; Standish VC; Arango-Lasprilla JC; Tirado VM; Ossa JM; Goate AM; Kosik KS; Lopera F
    J Clin Exp Neuropsychol; 2000 Aug; 22(4):483-95. PubMed ID: 10923058
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study.
    Acosta-Baena N; Sepulveda-Falla D; Lopera-Gómez CM; Jaramillo-Elorza MC; Moreno S; Aguirre-Acevedo DC; Saldarriaga A; Lopera F
    Lancet Neurol; 2011 Mar; 10(3):213-20. PubMed ID: 21296022
    [TBL] [Abstract][Full Text] [Related]  

  • 6. APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease.
    Vélez JI; Lopera F; Sepulveda-Falla D; Patel HR; Johar AS; Chuah A; Tobón C; Rivera D; Villegas A; Cai Y; Peng K; Arkell R; Castellanos FX; Andrews SJ; Silva Lara MF; Creagh PK; Easteal S; de Leon J; Wong ML; Licinio J; Mastronardi CA; Arcos-Burgos M
    Mol Psychiatry; 2016 Jul; 21(7):916-24. PubMed ID: 26619808
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rare causes of early-onset dystonia-parkinsonism with cognitive impairment: a de novo PSEN-1 mutation.
    Carecchio M; Picillo M; Valletta L; Elia AE; Haack TB; Cozzolino A; Vitale A; Garavaglia B; Iuso A; Bagella CF; Pappatà S; Barone P; Prokisch H; Romito L; Tiranti V
    Neurogenetics; 2017 Jul; 18(3):175-178. PubMed ID: 28664294
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutation screening in Chinese patients with familial Alzheimer's disease by whole-exome sequencing.
    Jiang B; Zhou J; Li HL; Chen YG; Cheng HR; Ye LQ; Liu DS; Chen DF; Tao QQ; Wu ZY
    Neurobiol Aging; 2019 Apr; 76():215.e15-215.e21. PubMed ID: 30598257
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer's disease profile and possible mechanisms of disease protection.
    Almeida MC; Eger SJ; He C; Audouard M; Nikitina A; Glasauer SMK; Han D; Mejía-Cupajita B; Acosta-Uribe J; Villalba-Moreno ND; Littau JL; Elcheikhali M; Rivera EK; Carrettiero DC; Villegas-Lanau CA; Sepulveda-Falla D; Lopera F; Kosik KS
    Neuron; 2024 Jun; 112(11):1778-1794.e7. PubMed ID: 38417436
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Mutation in DAOA Modifies the Age of Onset in PSEN1 E280A Alzheimer's Disease.
    Vélez JI; Rivera D; Mastronardi CA; Patel HR; Tobón C; Villegas A; Cai Y; Easteal S; Lopera F; Arcos-Burgos M
    Neural Plast; 2016; 2016():9760314. PubMed ID: 26949549
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis.
    Islam S; Sun Y; Gao Y; Nakamura T; Noorani AA; Li T; Wong PC; Kimura N; Matsubara E; Kasuga K; Ikeuchi T; Tomita T; Zou K; Michikawa M
    J Neurosci; 2022 Feb; 42(8):1574-1586. PubMed ID: 34987110
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A Three-Factor Structure of Cognitive Functioning Among Unimpaired Carriers and Non-Carriers of Autosomal-Dominant Alzheimer's Disease.
    Guzmán-Vélez E; Jaimes S; Aguirre-Acevedo DC; Norton DJ; Papp KV; Amariglio R; Rentz D; Baena A; Henao E; Tirado V; Muñoz C; Giraldo M; Sperling RA; Lopera F; Quiroz YT
    J Alzheimers Dis; 2018; 65(1):107-115. PubMed ID: 30040714
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer's disease.
    Sepulveda-Falla D; Chavez-Gutierrez L; Portelius E; Vélez JI; Dujardin S; Barrera-Ocampo A; Dinkel F; Hagel C; Puig B; Mastronardi C; Lopera F; Hyman BT; Blennow K; Arcos-Burgos M; de Strooper B; Glatzel M
    Acta Neuropathol; 2021 Feb; 141(2):217-233. PubMed ID: 33319314
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Influence of low frequency PSEN1 variants on familial Alzheimer's disease risk in Brazil.
    Abdala BB; Dos Santos JM; Gonçalves AP; da Motta LB; Laks J; de Borges MB; Gonçalves Pimentel MM; Santos-Rebouças CB
    Neurosci Lett; 2017 Jul; 653():341-345. PubMed ID: 28554858
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Diagnostic accuracy of CERAD total score in a Colombian cohort with mild cognitive impairment and Alzheimer's disease affected by E280A mutation on presenilin-1 gene.
    Aguirre-Acevedo DC; Jaimes-Barragán F; Henao E; Tirado V; Muñoz C; Reiman EM; Tariot PN; Langbaum JB; Lopera F
    Int Psychogeriatr; 2016 Mar; 28(3):503-10. PubMed ID: 26478578
    [TBL] [Abstract][Full Text] [Related]  

  • 16. (-)-Epigallocatechin-3-Gallate Diminishes Intra-and Extracellular Amyloid-Induced Cytotoxic Effects on Cholinergic-like Neurons from Familial Alzheimer's Disease PSEN1 E280A.
    Soto-Mercado V; Mendivil-Perez M; Velez-Pardo C; Jimenez-Del-Rio M
    Biomolecules; 2021 Dec; 11(12):. PubMed ID: 34944489
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study.
    Reiman EM; Quiroz YT; Fleisher AS; Chen K; Velez-Pardo C; Jimenez-Del-Rio M; Fagan AM; Shah AR; Alvarez S; Arbelaez A; Giraldo M; Acosta-Baena N; Sperling RA; Dickerson B; Stern CE; Tirado V; Munoz C; Reiman RA; Huentelman MJ; Alexander GE; Langbaum JB; Kosik KS; Tariot PN; Lopera F
    Lancet Neurol; 2012 Dec; 11(12):1048-56. PubMed ID: 23137948
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutation profile of APP, PSEN1, and PSEN2 in Chinese familial Alzheimer's disease.
    Gao Y; Ren RJ; Zhong ZL; Dammer E; Zhao QH; Shan S; Zhou Z; Li X; Zhang YQ; Cui HL; Hu YB; Chen SD; Chen JJ; Guo QH; Wang G
    Neurobiol Aging; 2019 May; 77():154-157. PubMed ID: 30822634
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An 1H-MRS framework predicts the onset of Alzheimer's disease symptoms in PSEN1 mutation carriers.
    Londono AC; Castellanos FX; Arbelaez A; Ruiz A; Aguirre-Acevedo DC; Richardson AM; Easteal S; Lidbury BA; Arcos-Burgos M; Lopera F
    Alzheimers Dement; 2014 Sep; 10(5):552-61. PubMed ID: 24239247
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PSEN1 G417S mutation in a Chinese pedigree causing early-onset parkinsonism with cognitive impairment.
    Jiang L; Qin Y; Zhao YW; Zeng Q; Pan HX; Liu ZH; Sun QY; Xu Q; Tan JQ; Yan XX; Li JC; Tang BS; Guo JF
    Neurobiol Aging; 2022 Jul; 115():70-76. PubMed ID: 35489321
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.