BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

279 related articles for article (PubMed ID: 38454456)

  • 1. GBA1 inactivation in oligodendrocytes affects myelination and induces neurodegenerative hallmarks and lipid dyshomeostasis in mice.
    Gregorio I; Russo L; Torretta E; Barbacini P; Contarini G; Pacinelli G; Bizzotto D; Moriggi M; Braghetta P; Papaleo F; Gelfi C; Moro E; Cescon M
    Mol Neurodegener; 2024 Mar; 19(1):22. PubMed ID: 38454456
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Glucocerebrosidase deficiency in dopaminergic neurons induces microglial activation without neurodegeneration.
    Soria FN; Engeln M; Martinez-Vicente M; Glangetas C; López-González MJ; Dovero S; Dehay B; Normand E; Vila M; Favereaux A; Georges F; Lo Bianco C; Bezard E; Fernagut PO
    Hum Mol Genet; 2017 Jul; 26(14):2603-2615. PubMed ID: 28520872
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Lysosomal trafficking defects link Parkinson's disease with Gaucher's disease.
    Wong YC; Krainc D
    Mov Disord; 2016 Nov; 31(11):1610-1618. PubMed ID: 27619775
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The relationship between glucocerebrosidase mutations and Parkinson disease.
    Migdalska-Richards A; Schapira AH
    J Neurochem; 2016 Oct; 139 Suppl 1(Suppl Suppl 1):77-90. PubMed ID: 26860875
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Parkinson's disease: acid-glucocerebrosidase activity and alpha-synuclein clearance.
    Blanz J; Saftig P
    J Neurochem; 2016 Oct; 139 Suppl 1():198-215. PubMed ID: 26860955
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glucocerebrosidase modulates cognitive and motor activities in murine models of Parkinson's disease.
    Rockenstein E; Clarke J; Viel C; Panarello N; Treleaven CM; Kim C; Spencer B; Adame A; Park H; Dodge JC; Cheng SH; Shihabuddin LS; Masliah E; Sardi SP
    Hum Mol Genet; 2016 Jul; 25(13):2645-2660. PubMed ID: 27126635
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gaucher-related synucleinopathies: the examination of sporadic neurodegeneration from a rare (disease) angle.
    Sardi SP; Cheng SH; Shihabuddin LS
    Prog Neurobiol; 2015 Feb; 125():47-62. PubMed ID: 25573151
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lysosomal functions and dysfunctions: Molecular and cellular mechanisms underlying Gaucher disease and its association with Parkinson disease.
    Horowitz M; Braunstein H; Zimran A; Revel-Vilk S; Goker-Alpan O
    Adv Drug Deliv Rev; 2022 Aug; 187():114402. PubMed ID: 35764179
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies.
    Sardi SP; Clarke J; Viel C; Chan M; Tamsett TJ; Treleaven CM; Bu J; Sweet L; Passini MA; Dodge JC; Yu WH; Sidman RL; Cheng SH; Shihabuddin LS
    Proc Natl Acad Sci U S A; 2013 Feb; 110(9):3537-42. PubMed ID: 23297226
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Acid ceramidase involved in pathogenic cascade leading to accumulation of α-synuclein in iPSC model of GBA1-associated Parkinson's disease.
    Kumar M; Srikanth MP; Deleidi M; Hallett PJ; Isacson O; Feldman RA
    Hum Mol Genet; 2023 May; 32(11):1888-1900. PubMed ID: 36752535
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Glucocerebrosidase and its relevance to Parkinson disease.
    Do J; McKinney C; Sharma P; Sidransky E
    Mol Neurodegener; 2019 Aug; 14(1):36. PubMed ID: 31464647
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death.
    Keatinge M; Bui H; Menke A; Chen YC; Sokol AM; Bai Q; Ellett F; Da Costa M; Burke D; Gegg M; Trollope L; Payne T; McTighe A; Mortiboys H; de Jager S; Nuthall H; Kuo MS; Fleming A; Schapira AH; Renshaw SA; Highley JR; Chacinska A; Panula P; Burton EA; O'Neill MJ; Bandmann O
    Hum Mol Genet; 2015 Dec; 24(23):6640-52. PubMed ID: 26376862
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice.
    Rocha EM; Smith GA; Park E; Cao H; Graham AR; Brown E; McLean JR; Hayes MA; Beagan J; Izen SC; Perez-Torres E; Hallett PJ; Isacson O
    Antioxid Redox Signal; 2015 Aug; 23(6):550-64. PubMed ID: 26094487
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease.
    Murphy KE; Gysbers AM; Abbott SK; Tayebi N; Kim WS; Sidransky E; Cooper A; Garner B; Halliday GM
    Brain; 2014 Mar; 137(Pt 3):834-48. PubMed ID: 24477431
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PGRN deficiency exacerbates, whereas a brain penetrant PGRN derivative protects,
    Zhao X; Lin Y; Liou B; Fu W; Jian J; Fannie V; Zhang W; Setchell KDR; Grabowski GA; Sun Y; Liu CJ
    Proc Natl Acad Sci U S A; 2023 Jan; 120(1):e2210442120. PubMed ID: 36574647
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glucocerebrosidase dysfunction in neurodegenerative disease.
    Brooker SM; Krainc D
    Essays Biochem; 2021 Dec; 65(7):873-883. PubMed ID: 34528667
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin.
    Kinghorn KJ; Grönke S; Castillo-Quan JI; Woodling NS; Li L; Sirka E; Gegg M; Mills K; Hardy J; Bjedov I; Partridge L
    J Neurosci; 2016 Nov; 36(46):11654-11670. PubMed ID: 27852774
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutant GBA1 expression and synucleinopathy risk: first insights from cellular and mouse models.
    Sardi SP; Singh P; Cheng SH; Shihabuddin LS; Schlossmacher MG
    Neurodegener Dis; 2012; 10(1-4):195-202. PubMed ID: 22327140
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes).
    Nakanishi E; Uemura N; Akiyama H; Kinoshita M; Masanori S; Taruno Y; Yamakado H; Matsuzawa SI; Takeda S; Hirabayashi Y; Takahashi R
    Mol Brain; 2021 May; 14(1):80. PubMed ID: 33971917
    [TBL] [Abstract][Full Text] [Related]  

  • 20. D409H GBA1 mutation accelerates the progression of pathology in A53T α-synuclein transgenic mouse model.
    Kim D; Hwang H; Choi S; Kwon SH; Lee S; Park JH; Kim S; Ko HS
    Acta Neuropathol Commun; 2018 Apr; 6(1):32. PubMed ID: 29703245
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.