BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 38458300)

  • 1. XQZ3, a Chlorella pyrenoidosa polysaccharide suppresses cancer progression by restraining mitochondrial bioenergetics via HSP90/AKT signaling pathway.
    Sun L; Ji M; Liu Y; Zhang M; Zheng C; Wang P
    Int J Biol Macromol; 2024 Apr; 264(Pt 2):130705. PubMed ID: 38458300
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A Homogeneous Polysaccharide from Fructus Schisandra chinensis (Turz.) Baill Induces Mitochondrial Apoptosis through the Hsp90/AKT Signalling Pathway in HepG2 Cells.
    Chen Y; Shi S; Wang H; Li N; Su J; Chou G; Wang S
    Int J Mol Sci; 2016 Jun; 17(7):. PubMed ID: 27367669
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Physicochemical characterization and antioxidant effects of green microalga Chlorella pyrenoidosa polysaccharide by regulation of microRNAs and gut microbiota in Caenorhabditis elegans.
    Wan X; Li X; Liu D; Gao X; Chen Y; Chen Z; Fu C; Lin L; Liu B; Zhao C
    Int J Biol Macromol; 2021 Jan; 168():152-162. PubMed ID: 33301848
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Heat shock protein 90 relieves heat stress damage of myocardial cells by regulating Akt and PKM2 signaling in vivo.
    Zhang XH; Wu JX; Sha JZ; Yang B; Sun JR; Bao ED
    Int J Mol Med; 2020 Jun; 45(6):1888-1908. PubMed ID: 32236591
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Hsp90 inhibitor SNX-2112, induces apoptosis in multidrug resistant K562/ADR cells through suppression of Akt/NF-κB and disruption of mitochondria-dependent pathways.
    Wang R; Shao F; Liu Z; Zhang J; Wang S; Liu J; Liu H; Chen H; Liu K; Xia M; Wang Y
    Chem Biol Interact; 2013 Sep; 205(1):1-10. PubMed ID: 23777986
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Blocking NF-κB and Akt by Hsp90 inhibition sensitizes Smac mimetic compound 3-induced extrinsic apoptosis pathway and results in synergistic cancer cell death.
    Bai L; Xu S; Chen W; Li Z; Wang X; Tang H; Lin Y
    Apoptosis; 2011 Jan; 16(1):45-54. PubMed ID: 20862547
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of cell death by a novel 16.2 kD heat shock protein predominantly via Hsp90 mediated lipid rafts stabilization and Akt activation pathway.
    Bellyei S; Szigeti A; Boronkai A; Pozsgai E; Gomori E; Melegh B; Janaky T; Bognar Z; Hocsak E; Sumegi B; Gallyas F
    Apoptosis; 2007 Jan; 12(1):97-112. PubMed ID: 17136496
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting PI3K/Akt/HSP90 signaling sensitizes gastric cancer cells to deoxycholate-induced apoptosis.
    Redlak MJ; Miller TA
    Dig Dis Sci; 2011 Feb; 56(2):323-9. PubMed ID: 20585984
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hsp90 Relieves Heat Stress-Induced Damage in Mouse Kidneys: Involvement of Antiapoptotic PKM2-AKT and Autophagic HIF-1α Signaling.
    Chen B; Yang B; Zhu J; Wu J; Sha J; Sun J; Bao E; Zhang X
    Int J Mol Sci; 2020 Feb; 21(5):. PubMed ID: 32121259
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt Lymphoma.
    Giulino-Roth L; van Besien HJ; Dalton T; Totonchy JE; Rodina A; Taldone T; Bolaender A; Erdjument-Bromage H; Sadek J; Chadburn A; Barth MJ; Dela Cruz FS; Rainey A; Kung AL; Chiosis G; Cesarman E
    Mol Cancer Ther; 2017 Sep; 16(9):1779-1790. PubMed ID: 28619753
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anti-apoptotic effect of heat shock protein 90 on hypoxia-mediated cardiomyocyte damage is mediated via the phosphatidylinositol 3-kinase/AKT pathway.
    Wang W; Peng Y; Wang Y; Zhao X; Yuan Z
    Clin Exp Pharmacol Physiol; 2009 Sep; 36(9):899-903. PubMed ID: 19298537
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 3'-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells.
    Sun Y; Huang YH; Huang FY; Mei WL; Liu Q; Wang CC; Lin YY; Huang C; Li YN; Dai HF; Tan GH
    Theranostics; 2018; 8(7):2044-2060. PubMed ID: 29556372
    [No Abstract]   [Full Text] [Related]  

  • 13. BJ-B11, a novel Hsp90 inhibitor, induces apoptosis in human chronic myeloid leukemia K562 cells through the mitochondria-dependent pathway.
    Ju HQ; Wang SX; Xiang YF; Liu Z; Liu JY; Chen ZP; Zeng FL; Xia M; Liu ZH; Xing GW; Wang SY; Wang YF
    Eur J Pharmacol; 2011 Sep; 666(1-3):26-34. PubMed ID: 21620825
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel Functional Role of Heat Shock Protein 90 in Mitochondrial Connexin 43-Mediated Hypoxic Postconditioning.
    Tu RH; Li QJ; Huang Z; He Y; Meng JJ; Zheng HL; Zeng ZY; Zhong GQ
    Cell Physiol Biochem; 2017; 44(3):982-997. PubMed ID: 29179175
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of gastric tumor growth by a novel Hsp90 inhibitor.
    Lu C; Liu D; Jin J; Deokar H; Zhang Y; Buolamwini JK; Yu X; Yan C; Chen X
    Biochem Pharmacol; 2013 May; 85(9):1246-56. PubMed ID: 23415900
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Elevated expression of HSP90 and the antitumor effect of an HSP90 inhibitor via inactivation of the Akt/mTOR pathway in undifferentiated pleomorphic sarcoma.
    Bekki H; Kohashi K; Maekawa A; Yamada Y; Yamamoto H; Harimaya K; Hakozaki M; Nabeshima K; Iwamoto Y; Oda Y
    BMC Cancer; 2015 Oct; 15():804. PubMed ID: 26502919
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The selective Hsp90 inhibitor BJ-B11 exhibits potent antitumor activity via induction of cell cycle arrest, apoptosis and autophagy in Eca-109 human esophageal squamous carcinoma cells.
    Liu KS; Zhang Y; Ding WC; Wang SX; Xiang YF; Yang P; Chen ZP; Zheng K; Liu Z; Xia M; Wang YF
    Int J Oncol; 2012 Dec; 41(6):2276-84. PubMed ID: 23076967
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synuclein γ protects Akt and mTOR and renders tumor resistance to Hsp90 disruption.
    Liang W; Miao S; Zhang B; He S; Shou C; Manivel P; Krishna R; Chen Y; Shi YE
    Oncogene; 2015 Apr; 34(18):2398-405. PubMed ID: 24954510
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells.
    Pan Z; Chen Y; Pang H; Wang X; Zhang Y; Xie X; He G
    Eur J Med Chem; 2022 Nov; 242():114674. PubMed ID: 35987020
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mitochondrial HSP90 Accumulation Promotes Vascular Remodeling in Pulmonary Arterial Hypertension.
    Boucherat O; Peterlini T; Bourgeois A; Nadeau V; Breuils-Bonnet S; Boilet-Molez S; Potus F; Meloche J; Chabot S; Lambert C; Tremblay E; Chae YC; Altieri DC; Sutendra G; Michelakis ED; Paulin R; Provencher S; Bonnet S
    Am J Respir Crit Care Med; 2018 Jul; 198(1):90-103. PubMed ID: 29394093
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.