BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 38465776)

  • 1. Evaluation of the usefulness of plasma 4β-hydroxycholesterol concentration normalized by 4α-hydroxycholesterol for accurate CYP3A phenotyping.
    Oda A; Suzuki Y; Sato H; Koyama T; Nakatochi M; Momozawa Y; Tanaka R; Ono H; Tatsuta R; Ando T; Shin T; Wakai K; Matsuo K; Itoh H; Ohno K
    Clin Transl Sci; 2024 Mar; 17(3):e13768. PubMed ID: 38465776
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluation of effects of indoxyl sulfate and parathyroid hormone on CYP3A activity considering the influence of CYP3A5 gene polymorphisms.
    Oda A; Suzuki Y; Yoshijima C; Sato H; Tanaka R; Ono H; Tatsuta R; Ando T; Shin T; Itoh H; Ohno K
    Br J Clin Pharmacol; 2023 Dec; 89(12):3648-3658. PubMed ID: 37522799
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sensitive UHPLC-MS/MS quantification method for 4β- and 4α-hydroxycholesterol in plasma for accurate CYP3A phenotyping.
    Suzuki Y; Oda A; Negami J; Toyama D; Tanaka R; Ono H; Ando T; Shin T; Mimata H; Itoh H; Ohno K
    J Lipid Res; 2022 Mar; 63(3):100184. PubMed ID: 35181316
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pregnancy Increases CYP3A Enzymes Activity as Measured by the 4β-Hydroxycholesterol/Cholesterol Ratio.
    Mlugu EM; Minzi OM; Kamuhabwa AAR; Diczfalusy U; Aklillu E
    Int J Mol Sci; 2022 Dec; 23(23):. PubMed ID: 36499500
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans.
    Diczfalusy U; Nylén H; Elander P; Bertilsson L
    Br J Clin Pharmacol; 2011 Feb; 71(2):183-9. PubMed ID: 21219398
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative performance of oral midazolam clearance and plasma 4β-hydroxycholesterol to explain interindividual variability in tacrolimus clearance.
    Vanhove T; de Jonge H; de Loor H; Annaert P; Diczfalusy U; Kuypers DR
    Br J Clin Pharmacol; 2016 Dec; 82(6):1539-1549. PubMed ID: 27501475
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 4β-Hydroxycholesterol as an Endogenous Biomarker for CYP3A Activity: Literature Review and Critical Evaluation.
    Penzak SR; Rojas-Fernandez C
    J Clin Pharmacol; 2019 May; 59(5):611-624. PubMed ID: 30748026
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sex and CYP3A5 genotype influence total CYP3A activity: high CYP3A activity and a unique distribution of CYP3A5 variant alleles in Ethiopians.
    Gebeyehu E; Engidawork E; Bijnsdorp A; Aminy A; Diczfalusy U; Aklillu E
    Pharmacogenomics J; 2011 Apr; 11(2):130-7. PubMed ID: 20231858
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impact of CYP3A5 genotype on tolvaptan pharmacokinetics and their relationships with endogenous markers of CYP3A activity and serum sodium level in heart failure patients.
    Hoshikawa K; Naito T; Akutsu S; Saotome M; Maekawa Y; Kawakami J
    Basic Clin Pharmacol Toxicol; 2020 Apr; 126(4):353-363. PubMed ID: 31652395
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians.
    Diczfalusy U; Miura J; Roh HK; Mirghani RA; Sayi J; Larsson H; Bodin KG; Allqvist A; Jande M; Kim JW; Aklillu E; Gustafsson LL; Bertilsson L
    Pharmacogenet Genomics; 2008 Mar; 18(3):201-8. PubMed ID: 18300941
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Use of 4β-Hydroxycholesterol Plasma Concentrations as an Endogenous Biomarker of CYP3A Activity: Clinical Validation in Individuals With Type 2 Diabetes.
    Gravel S; Chiasson JL; Gaudette F; Turgeon J; Michaud V
    Clin Pharmacol Ther; 2019 Oct; 106(4):831-840. PubMed ID: 31002385
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 4β-hydroxycholesterol as an endogenous CYP3A marker in cancer patients treated with taxanes.
    de Graan AJ; Sparreboom A; de Bruijn P; de Jonge E; van der Holt B; Wiemer EA; Verweij J; Mathijssen RH; van Schaik RH
    Br J Clin Pharmacol; 2015 Sep; 80(3):560-8. PubMed ID: 26119961
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Relationship between the plasma fentanyl and serum 4β-hydroxycholesterol based on CYP3A5 genotype and gender in patients with cancer pain.
    Ishida T; Naito T; Sato H; Kawakami J
    Drug Metab Pharmacokinet; 2016 Jun; 31(3):242-8. PubMed ID: 27236640
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Relationships between endogenous CYP3A markers and plasma amlodipine exposure and metabolism in early postpartum and non-peripartum women with hypertension.
    Taguchi R; Naito T; Kubono N; Ogawa N; Itoh H; Kawakami J
    Pregnancy Hypertens; 2019 Jul; 17():209-215. PubMed ID: 31487643
    [TBL] [Abstract][Full Text] [Related]  

  • 15. No impact of vitamin D on the CYP3A biomarker 4β-hydroxycholesterol in patients with abnormal glucose regulation.
    Mannheimer B; Wagner H; Östenson CG; Diczfalusy U
    PLoS One; 2015; 10(4):e0121984. PubMed ID: 25835492
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Improved synthesis and in vitro evaluation of the cytotoxic profile of oxysterols oxidized at C4 (4α- and 4β-hydroxycholesterol) and C7 (7-ketocholesterol, 7α- and 7β-hydroxycholesterol) on cells of the central nervous system.
    Nury T; Samadi M; Zarrouk A; Riedinger JM; Lizard G
    Eur J Med Chem; 2013; 70():558-67. PubMed ID: 24211631
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 4β-Hydroxycholesterol as an endogenous biomarker of CYP3A activity in cynomolgus monkeys.
    Li K; Zhao S; Zhang L; Wu X; Shu P; Wang Y; Feng H; Gu Z; Han Hsu H
    Drug Metab Dispos; 2014 May; 42(5):839-43. PubMed ID: 24595680
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recommendations on the Development of a Bioanalytical Assay for 4β-Hydroxycholesterol, an Emerging Endogenous Biomarker of CYP3A Activity.
    Aubry AF; Dean B; Diczfalusy U; Goodenough A; Iffland A; McLeod J; Weng N; Yang Z
    AAPS J; 2016 Sep; 18(5):1056-1066. PubMed ID: 27350147
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Association of plasma concentration of 4β-hydroxycholesterol with CYP3A5 polymorphism and plasma concentration of indoxyl sulfate in stable kidney transplant recipients.
    Suzuki Y; Itoh H; Fujioka T; Sato F; Kawasaki K; Sato Y; Sato Y; Ohno K; Mimata H; Kishino S
    Drug Metab Dispos; 2014 Jan; 42(1):105-10. PubMed ID: 24135442
    [TBL] [Abstract][Full Text] [Related]  

  • 20. CYP3A activity based on plasma 4β-hydroxycholesterol during the early postpartum period has an effect on the plasma disposition of amlodipine.
    Naito T; Kubono N; Ishida T; Deguchi S; Sugihara M; Itoh H; Kanayama N; Kawakami J
    Drug Metab Pharmacokinet; 2015 Dec; 30(6):419-24. PubMed ID: 26654672
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.