162 related articles for article (PubMed ID: 38465923)
1. Beyond the hype and toward application: liver complex in vitro models in preclinical drug safety.
Jadalannagari S; Ewart L
Expert Opin Drug Metab Toxicol; 2024 Mar; ():1-13. PubMed ID: 38465923
[TBL] [Abstract][Full Text] [Related]
2. Integrating Liver-Chip data into pharmaceutical decision-making processes.
Levner D; Ewart L
Expert Opin Drug Discov; 2023; 18(12):1313-1320. PubMed ID: 37700537
[TBL] [Abstract][Full Text] [Related]
3. Current limitations and future opportunities for prediction of DILI from in vitro.
Funk C; Roth A
Arch Toxicol; 2017 Jan; 91(1):131-142. PubMed ID: 27766365
[TBL] [Abstract][Full Text] [Related]
4. Recommended Guidelines for Developing, Qualifying, and Implementing Complex In Vitro Models (CIVMs) for Drug Discovery.
Ekert JE; Deakyne J; Pribul-Allen P; Terry R; Schofield C; Jeong CG; Storey J; Mohamet L; Francis J; Naidoo A; Amador A; Klein JL; Rowan W
SLAS Discov; 2020 Dec; 25(10):1174-1190. PubMed ID: 32495689
[TBL] [Abstract][Full Text] [Related]
5. Comprehensive Evaluation of Organotypic and Microphysiological Liver Models for Prediction of Drug-Induced Liver Injury.
Zhou Y; Shen JX; Lauschke VM
Front Pharmacol; 2019; 10():1093. PubMed ID: 31616302
[TBL] [Abstract][Full Text] [Related]
6. Perspectives on the evaluation and adoption of complex in vitro models in drug development: Workshop with the FDA and the pharmaceutical industry (IQ MPS Affiliate).
Baran SW; Brown PC; Baudy AR; Fitzpatrick SC; Frantz C; Fullerton A; Gan J; Hardwick RN; Hillgren KM; Kopec AK; Liras JL; Mendrick DL; Nagao R; Proctor WR; Ramsden D; Ribeiro AJS; Stresser D; Sung KE; Sura R; Tetsuka K; Tomlinson L; Van Vleet T; Wagoner MP; Wang Q; Arslan SY; Yoder G; Ekert JE
ALTEX; 2022; 39(2):297–314. PubMed ID: 35064273
[TBL] [Abstract][Full Text] [Related]
7. The Liver Toxicity Knowledge Base (LKTB) and drug-induced liver injury (DILI) classification for assessment of human liver injury.
Thakkar S; Chen M; Fang H; Liu Z; Roberts R; Tong W
Expert Rev Gastroenterol Hepatol; 2018 Jan; 12(1):31-38. PubMed ID: 28931315
[TBL] [Abstract][Full Text] [Related]
8. Drug-induced liver injury and drug development: industry perspective.
Regev A
Semin Liver Dis; 2014 May; 34(2):227-39. PubMed ID: 24879986
[TBL] [Abstract][Full Text] [Related]
9. Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans.
Atienzar FA; Blomme EA; Chen M; Hewitt P; Kenna JG; Labbe G; Moulin F; Pognan F; Roth AB; Suter-Dick L; Ukairo O; Weaver RJ; Will Y; Dambach DM
Biomed Res Int; 2016; 2016():9737920. PubMed ID: 27689095
[TBL] [Abstract][Full Text] [Related]
10. An integrated biomimetic array chip for establishment of collagen-based 3D primary human hepatocyte model for prediction of clinical drug-induced liver injury.
Xiao RR; Lv T; Tu X; Li P; Wang T; Dong H; Tu P; Ai X
Biotechnol Bioeng; 2021 Dec; 118(12):4687-4698. PubMed ID: 34478150
[TBL] [Abstract][Full Text] [Related]
11. Advanced preclinical models for evaluation of drug-induced liver injury - consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET].
Fernandez-Checa JC; Bagnaninchi P; Ye H; Sancho-Bru P; Falcon-Perez JM; Royo F; Garcia-Ruiz C; Konu O; Miranda J; Lunov O; Dejneka A; Elfick A; McDonald A; Sullivan GJ; Aithal GP; Lucena MI; Andrade RJ; Fromenty B; Kranendonk M; Cubero FJ; Nelson LJ
J Hepatol; 2021 Oct; 75(4):935-959. PubMed ID: 34171436
[TBL] [Abstract][Full Text] [Related]
12. Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man.
Dragovic S; Vermeulen NP; Gerets HH; Hewitt PG; Ingelman-Sundberg M; Park BK; Juhila S; Snoeys J; Weaver RJ
Arch Toxicol; 2016 Dec; 90(12):2979-3003. PubMed ID: 27659300
[TBL] [Abstract][Full Text] [Related]
13. Development of novel tools for the in vitro investigation of drug-induced liver injury.
Jiang J; Wolters JE; van Breda SG; Kleinjans JC; de Kok TM
Expert Opin Drug Metab Toxicol; 2015; 11(10):1523-37. PubMed ID: 26155718
[TBL] [Abstract][Full Text] [Related]
14. Recent Progress in Prediction Systems for Drug-induced Liver Injury Using In vitro Cell Culture.
Ozawa S; Miura T; Terashima J; Habano W; Ishida S
Drug Metab Lett; 2021; 14(1):25-40. PubMed ID: 33267768
[TBL] [Abstract][Full Text] [Related]
15. Co-Culture of Human Primary Hepatocytes and Nonparenchymal Liver Cells in the Emulate® Liver-Chip for the Study of Drug-Induced Liver Injury.
Shi Q; Arefin A; Ren L; Papineau KS; Barnette DA; Schnackenberg LK; Hawes JJ; Avigan M; Mendrick DL; Ewart L; Ronxhi J
Curr Protoc; 2022 Jul; 2(7):e478. PubMed ID: 35790095
[TBL] [Abstract][Full Text] [Related]
16. Predicting Drug-Induced Liver Injury with Bayesian Machine Learning.
Williams DP; Lazic SE; Foster AJ; Semenova E; Morgan P
Chem Res Toxicol; 2020 Jan; 33(1):239-248. PubMed ID: 31535850
[TBL] [Abstract][Full Text] [Related]
17. Development of a Battery of
Rathman J; Yang C; Ribeiro JV; Mostrag A; Thakkar S; Tong W; Hobocienski B; Sacher O; Magdziarz T; Bienfait B
Chem Res Toxicol; 2021 Feb; 34(2):601-615. PubMed ID: 33356149
[TBL] [Abstract][Full Text] [Related]
18. Evaluation of a Three-Dimensional Primary Human Hepatocyte Spheroid Model: Adoption and Industrialization for the Enhanced Detection of Drug-Induced Liver Injury.
Schofield CA; Walker TM; Taylor MA; Patel M; Vlachou DF; Macina JM; Vidgeon-Hart MP; Williams A; McGill PJ; Newman CF; Sakatis MZ
Chem Res Toxicol; 2021 Dec; 34(12):2485-2499. PubMed ID: 34797640
[TBL] [Abstract][Full Text] [Related]
19. Current challenges and controversies in drug-induced liver injury.
Corsini A; Ganey P; Ju C; Kaplowitz N; Pessayre D; Roth R; Watkins PB; Albassam M; Liu B; Stancic S; Suter L; Bortolini M
Drug Saf; 2012 Dec; 35(12):1099-117. PubMed ID: 23137150
[TBL] [Abstract][Full Text] [Related]
20. The application of omics-based human liver platforms for investigating the mechanism of drug-induced hepatotoxicity in vitro.
Jiang J; Pieterman CD; Ertaylan G; Peeters RLM; de Kok TMCM
Arch Toxicol; 2019 Nov; 93(11):3067-3098. PubMed ID: 31586243
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]