BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

189 related articles for article (PubMed ID: 38472229)

  • 1. ZNF827 is a single-stranded DNA binding protein that regulates the ATR-CHK1 DNA damage response pathway.
    Yang SF; Nelson CB; Wells JK; Fernando M; Lu R; Allen JAM; Malloy L; Lamm N; Murphy VJ; Mackay JP; Deans AJ; Cesare AJ; Sobinoff AP; Pickett HA
    Nat Commun; 2024 Mar; 15(1):2210. PubMed ID: 38472229
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.
    Maréchal A; Li JM; Ji XY; Wu CS; Yazinski SA; Nguyen HD; Liu S; Jiménez AE; Jin J; Zou L
    Mol Cell; 2014 Jan; 53(2):235-246. PubMed ID: 24332808
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Human CTC1 promotes TopBP1 stability and CHK1 phosphorylation in response to telomere dysfunction and global replication stress.
    Ackerson SM; Gable CI; Stewart JA
    Cell Cycle; 2020 Dec; 19(24):3491-3507. PubMed ID: 33269665
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes.
    Zou L; Elledge SJ
    Science; 2003 Jun; 300(5625):1542-8. PubMed ID: 12791985
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling.
    Choi JH; Lindsey-Boltz LA; Kemp M; Mason AC; Wold MS; Sancar A
    Proc Natl Acad Sci U S A; 2010 Aug; 107(31):13660-5. PubMed ID: 20616048
    [TBL] [Abstract][Full Text] [Related]  

  • 6. ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation.
    Ball HL; Myers JS; Cortez D
    Mol Biol Cell; 2005 May; 16(5):2372-81. PubMed ID: 15743907
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alteration of replication protein A binding mode on single-stranded DNA by NSMF potentiates RPA phosphorylation by ATR kinase.
    Kang Y; Han YG; Khim KW; Choi WG; Ju MK; Park K; Shin KJ; Chae YC; Choi JH; Kim H; Lee JY
    Nucleic Acids Res; 2023 Aug; 51(15):7936-7950. PubMed ID: 37378431
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA.
    Zhang H; Head PE; Daddacha W; Park SH; Li X; Pan Y; Madden MZ; Duong DM; Xie M; Yu B; Warren MD; Liu EA; Dhere VR; Li C; Pradilla I; Torres MA; Wang Y; Dynan WS; Doetsch PW; Deng X; Seyfried NT; Gius D; Yu DS
    Cell Rep; 2016 Feb; 14(6):1435-1447. PubMed ID: 26854234
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress.
    Liu S; Opiyo SO; Manthey K; Glanzer JG; Ashley AK; Amerin C; Troksa K; Shrivastav M; Nickoloff JA; Oakley GG
    Nucleic Acids Res; 2012 Nov; 40(21):10780-94. PubMed ID: 22977173
    [TBL] [Abstract][Full Text] [Related]  

  • 10. APE1 recruits ATRIP to ssDNA in an RPA-dependent and -independent manner to promote the ATR DNA damage response.
    Lin Y; Li J; Zhao H; McMahon A; McGhee K; Yan S
    Elife; 2023 May; 12():. PubMed ID: 37216274
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of replication protein A by S-phase checkpoint kinases.
    Liu JS; Kuo SR; Melendy T
    DNA Repair (Amst); 2006 Mar; 5(3):369-80. PubMed ID: 16412704
    [TBL] [Abstract][Full Text] [Related]  

  • 12. RPA-coated single-stranded DNA promotes the ETAA1-dependent activation of ATR.
    Lyu K; Kumagai A; Dunphy WG
    Cell Cycle; 2019 Apr; 18(8):898-913. PubMed ID: 30975033
    [TBL] [Abstract][Full Text] [Related]  

  • 13. APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress.
    Willis J; Patel Y; Lentz BL; Yan S
    Proc Natl Acad Sci U S A; 2013 Jun; 110(26):10592-7. PubMed ID: 23754435
    [TBL] [Abstract][Full Text] [Related]  

  • 14. UV-induced ataxia-telangiectasia-mutated and Rad3-related (ATR) activation requires replication stress.
    Ward IM; Minn K; Chen J
    J Biol Chem; 2004 Mar; 279(11):9677-80. PubMed ID: 14742437
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNA-PK phosphorylation of RPA32 Ser4/Ser8 regulates replication stress checkpoint activation, fork restart, homologous recombination and mitotic catastrophe.
    Ashley AK; Shrivastav M; Nie J; Amerin C; Troksa K; Glanzer JG; Liu S; Opiyo SO; Dimitrova DD; Le P; Sishc B; Bailey SM; Oakley GG; Nickoloff JA
    DNA Repair (Amst); 2014 Sep; 21():131-9. PubMed ID: 24819595
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress.
    Kemp MG; Akan Z; Yilmaz S; Grillo M; Smith-Roe SL; Kang TH; Cordeiro-Stone M; Kaufmann WK; Abraham RT; Sancar A; Unsal-Kaçmaz K
    J Biol Chem; 2010 May; 285(22):16562-71. PubMed ID: 20233725
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The ATR signaling pathway is disabled during infection with the parvovirus minute virus of mice.
    Adeyemi RO; Pintel DJ
    J Virol; 2014 Sep; 88(17):10189-99. PubMed ID: 24965470
    [TBL] [Abstract][Full Text] [Related]  

  • 18. RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling.
    Lindsey-Boltz LA; Kemp MG; Capp C; Sancar A
    Cell Cycle; 2015; 14(1):99-108. PubMed ID: 25602520
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A phosphorylation-and-ubiquitylation circuitry driving ATR activation and homologous recombination.
    Dubois JC; Yates M; Gaudreau-Lapierre A; Clément G; Cappadocia L; Gaudreau L; Zou L; Maréchal A
    Nucleic Acids Res; 2017 Sep; 45(15):8859-8872. PubMed ID: 28666352
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1).
    Lindsey-Boltz LA; Sancar A
    J Biol Chem; 2011 Jun; 286(22):19229-36. PubMed ID: 21502314
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.