191 related articles for article (PubMed ID: 38475864)
1. Functionally-instructed modifiers of response to ATR inhibition in experimental glioma.
Walter B; Hirsch S; Kuhlburger L; Stahl A; Schnabel L; Wisser S; Haeusser LA; Tsiami F; Plöger S; Aghaallaei N; Dick AM; Skokowa J; Schmees C; Templin M; Schenke-Layland K; Tatagiba M; Nahnsen S; Merk DJ; Tabatabai G
J Exp Clin Cancer Res; 2024 Mar; 43(1):77. PubMed ID: 38475864
[TBL] [Abstract][Full Text] [Related]
2. Evaluation of [
Carlucci G; Carney B; Sadique A; Vansteene A; Tang J; Reiner T
Nucl Med Biol; 2017 May; 48():9-15. PubMed ID: 28157626
[TBL] [Abstract][Full Text] [Related]
3. Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress.
Lloyd RL; Urban V; Muñoz-Martínez F; Ayestaran I; Thomas JC; de Renty C; O'Connor MJ; Forment JV; Galanty Y; Jackson SP
Nucleic Acids Res; 2021 Sep; 49(15):8665-8683. PubMed ID: 34329458
[TBL] [Abstract][Full Text] [Related]
4. WEE1 inhibitor and ataxia telangiectasia and RAD3-related inhibitor trigger stimulator of interferon gene-dependent immune response and enhance tumor treatment efficacy through programmed death-ligand 1 blockade.
Wu X; Kang X; Zhang X; Xie W; Su Y; Liu X; Guo L; Guo E; Li F; Hu D; Qin X; Fu Y; Peng W; Jia J; Wang C
Cancer Sci; 2021 Nov; 112(11):4444-4456. PubMed ID: 34382294
[TBL] [Abstract][Full Text] [Related]
5. Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer.
Durinikova E; Reilly NM; Buzo K; Mariella E; Chilà R; Lorenzato A; Dias JML; Grasso G; Pisati F; Lamba S; Corti G; Degasperi A; Cancelliere C; Mauri G; Andrei P; Linnebacher M; Marsoni S; Siena S; Sartore-Bianchi A; Nik-Zainal S; Di Nicolantonio F; Bardelli A; Arena S
Clin Cancer Res; 2022 Sep; 28(17):3874-3889. PubMed ID: 35881546
[TBL] [Abstract][Full Text] [Related]
6. Recent Advances in Synergistic Antitumor Effects Exploited from the Inhibition of Ataxia Telangiectasia and RAD3-Related Protein Kinase (ATR).
Wang LW; Jiang S; Yuan YH; Duan J; Mao ND; Hui Z; Bai R; Xie T; Ye XY
Molecules; 2022 Apr; 27(8):. PubMed ID: 35458687
[TBL] [Abstract][Full Text] [Related]
7. Synergistic Effect of a Mesothelin-Targeted
Wickstroem K; Hagemann UB; Cruciani V; Wengner AM; Kristian A; Ellingsen C; Siemeister G; Bjerke RM; Karlsson J; Ryan OB; Linden L; Mumberg D; Ziegelbauer K; Cuthbertson AS
J Nucl Med; 2019 Sep; 60(9):1293-1300. PubMed ID: 30850485
[TBL] [Abstract][Full Text] [Related]
8. Targeted inhibition of the ATR/CHK1 pathway overcomes resistance to olaparib and dysregulates DNA damage response protein expression in BRCA2
Biegała Ł; Gajek A; Szymczak-Pajor I; Marczak A; Śliwińska A; Rogalska A
Sci Rep; 2023 Dec; 13(1):22659. PubMed ID: 38114660
[TBL] [Abstract][Full Text] [Related]
9. Camonsertib in DNA damage response-deficient advanced solid tumors: phase 1 trial results.
Yap TA; Fontana E; Lee EK; Spigel DR; Højgaard M; Lheureux S; Mettu NB; Carneiro BA; Carter L; Plummer R; Cote GM; Meric-Bernstam F; O'Connell J; Schonhoft JD; Wainszelbaum M; Fretland AJ; Manley P; Xu Y; Ulanet D; Rimkunas V; Zinda M; Koehler M; Silverman IM; Reis-Filho JS; Rosen E
Nat Med; 2023 Jun; 29(6):1400-1411. PubMed ID: 37277454
[TBL] [Abstract][Full Text] [Related]
10. SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance.
Llorca-Cardenosa MJ; Aronson LI; Krastev DB; Nieminuszczy J; Alexander J; Song F; Dylewska M; Broderick R; Brough R; Zimmermann A; Zenke FT; Gurel B; Riisnaes R; Ferreira A; Roumeliotis T; Choudhary J; Pettitt SJ; de Bono J; Cervantes A; Haider S; Niedzwiedz W; Lord CJ; Chong IY
Cancer Res; 2022 Nov; 82(21):3962-3973. PubMed ID: 36273494
[TBL] [Abstract][Full Text] [Related]
11. Targeting ATR in cancer medicine.
Sundar R; Brown J; Ingles Russo A; Yap TA
Curr Probl Cancer; 2017; 41(4):302-315. PubMed ID: 28662958
[TBL] [Abstract][Full Text] [Related]
12. Therapeutic Targeting of the DNA Damage Response Using an ATR Inhibitor in Biliary Tract Cancer.
Nam AR; Jin MH; Park JE; Bang JH; Oh DY; Bang YJ
Cancer Res Treat; 2019 Jul; 51(3):1167-1179. PubMed ID: 30514066
[TBL] [Abstract][Full Text] [Related]
13. Combining radiation and the ATR inhibitor berzosertib activates STING signaling and enhances immunotherapy via inhibiting SHP1 function in colorectal cancer.
Liu C; Wang X; Qin W; Tu J; Li C; Zhao W; Ma L; Liu B; Qiu H; Yuan X
Cancer Commun (Lond); 2023 Apr; 43(4):435-454. PubMed ID: 36855844
[TBL] [Abstract][Full Text] [Related]
14. Complete loss of ATM function augments replication catastrophe induced by ATR inhibition and gemcitabine in pancreatic cancer models.
Dunlop CR; Wallez Y; Johnson TI; Bernaldo de Quirós Fernández S; Durant ST; Cadogan EB; Lau A; Richards FM; Jodrell DI
Br J Cancer; 2020 Oct; 123(9):1424-1436. PubMed ID: 32741974
[TBL] [Abstract][Full Text] [Related]
15. Thymidine rescues ATR kinase inhibitor-induced deoxyuridine contamination in genomic DNA, cell death, and interferon-α/β expression.
Sugitani N; Vendetti FP; Cipriano AJ; Pandya P; Deppas JJ; Moiseeva TN; Schamus-Haynes S; Wang Y; Palmer D; Osmanbeyoglu HU; Bostwick A; Snyder NW; Gong YN; Aird KM; Delgoffe GM; Beumer JH; Bakkenist CJ
Cell Rep; 2022 Sep; 40(12):111371. PubMed ID: 36130512
[TBL] [Abstract][Full Text] [Related]
16. DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis.
Enriquez-Rios V; Dumitrache LC; Downing SM; Li Y; Brown EJ; Russell HR; McKinnon PJ
J Neurosci; 2017 Jan; 37(4):893-905. PubMed ID: 28123024
[TBL] [Abstract][Full Text] [Related]
17. Targeting ATR Pathway in Solid Tumors: Evidence of Improving Therapeutic Outcomes.
Mavroeidi D; Georganta A; Panagiotou E; Syrigos K; Souliotis VL
Int J Mol Sci; 2024 Feb; 25(5):. PubMed ID: 38474014
[TBL] [Abstract][Full Text] [Related]
18. Genome-wide CRISPR screens reveal synthetic lethality of RNASEH2 deficiency and ATR inhibition.
Wang C; Wang G; Feng X; Shepherd P; Zhang J; Tang M; Chen Z; Srivastava M; McLaughlin ME; Navone NM; Hart GT; Chen J
Oncogene; 2019 Apr; 38(14):2451-2463. PubMed ID: 30532030
[TBL] [Abstract][Full Text] [Related]
19. MGMT function determines the differential response of ATR inhibitors with DNA-damaging agents in glioma stem cells for GBM therapy.
Leong VWS; Khan S; Sharma P; Wu S; Thomas RR; Li X; Singh SK; Lang FF; Yung AWK; Koul D
Neurooncol Adv; 2024; 6(1):vdad165. PubMed ID: 38213834
[TBL] [Abstract][Full Text] [Related]
20. Resistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2.
O'Leary PC; Chen H; Doruk YU; Williamson T; Polacco B; McNeal AS; Shenoy T; Kale N; Carnevale J; Stevenson E; Quigley DA; Chou J; Feng FY; Swaney DL; Krogan NJ; Kim M; Diolaiti ME; Ashworth A
Cancer Res; 2022 Nov; 82(21):3950-3961. PubMed ID: 36273492
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
