BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 38483988)

  • 1. Epidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7.
    Boretto M; Geurts MH; Gandhi S; Ma Z; Staliarova N; Celotti M; Lim S; He GW; Millen R; Driehuis E; Begthel H; Smabers L; Roodhart J; van Es J; Wu W; Clevers H
    Proc Natl Acad Sci U S A; 2024 Mar; 121(12):e2309902121. PubMed ID: 38483988
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Role of FBXW7 in Gynecologic Malignancies.
    Di Fiore R; Suleiman S; Drago-Ferrante R; Subbannayya Y; Suleiman S; Vasileva-Slaveva M; Yordanov A; Pentimalli F; Giordano A; Calleja-Agius J
    Cells; 2023 May; 12(10):. PubMed ID: 37408248
    [TBL] [Abstract][Full Text] [Related]  

  • 3. E3 ubiquitin ligase FBXW7 enhances radiosensitivity of non-small cell lung cancer cells by inhibiting SOX9 regulation of CDKN1A through ubiquitination.
    Zhu H; Wang X; Zhou X; Lu S; Gu G; Liu C
    Lab Invest; 2022 Nov; 102(11):1203-1213. PubMed ID: 35840806
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Recent insight into the role of FBXW7 as a tumor suppressor.
    Yumimoto K; Nakayama KI
    Semin Cancer Biol; 2020 Dec; 67(Pt 2):1-15. PubMed ID: 32113998
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The ubiquitin ligase FBXW7 targets the centriolar assembly protein HsSAS-6 for degradation and thereby regulates centriole duplication.
    Badarudeen B; Gupta R; Nair SV; Chandrasekharan A; Manna TK
    J Biol Chem; 2020 Apr; 295(14):4428-4437. PubMed ID: 32086376
    [TBL] [Abstract][Full Text] [Related]  

  • 6. F-box and WD repeat domain-containing-7 (Fbxw7) protein targets endoplasmic reticulum-anchored osteogenic and chondrogenic transcriptional factors for degradation.
    Yumimoto K; Matsumoto M; Onoyama I; Imaizumi K; Nakayama KI
    J Biol Chem; 2013 Oct; 288(40):28488-502. PubMed ID: 23955342
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The FBXW7-NOTCH interactome: A ubiquitin proteasomal system-induced crosstalk modulating oncogenic transformation in human tissues.
    Kar R; Jha SK; Ojha S; Sharma A; Dholpuria S; Raju VSR; Prasher P; Chellappan DK; Gupta G; Kumar Singh S; Paudel KR; Hansbro PM; Kumar Singh S; Ruokolainen J; Kesari KK; Dua K; Jha NK
    Cancer Rep (Hoboken); 2021 Aug; 4(4):e1369. PubMed ID: 33822486
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ubiquitylation of unphosphorylated c-myc by novel E3 ligase SCF
    Bajpai S; Jin HR; Mucha B; Diehl JA
    Cancer Biol Ther; 2022 Dec; 23(1):348-357. PubMed ID: 35438057
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of FBXW7 in the quiescence of gefitinib-resistant lung cancer stem cells in EGFR-mutant non-small cell lung cancer.
    Hidayat M; Mitsuishi Y; Takahashi F; Tajima K; Yae T; Miyahara K; Hayakawa D; Winardi W; Ihara H; Koinuma Y; Wirawan A; Nurwidya F; Kato M; Kobayashi I; Sasaki S; Takamochi K; Hayashi T; Suehara Y; Moriyama M; Moriyama H; Habu S; Takahashi K
    Bosn J Basic Med Sci; 2019 Nov; 19(4):355-367. PubMed ID: 31202256
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FBXW7/hCDC4 is a general tumor suppressor in human cancer.
    Akhoondi S; Sun D; von der Lehr N; Apostolidou S; Klotz K; Maljukova A; Cepeda D; Fiegl H; Dafou D; Marth C; Mueller-Holzner E; Corcoran M; Dagnell M; Nejad SZ; Nayer BN; Zali MR; Hansson J; Egyhazi S; Petersson F; Sangfelt P; Nordgren H; Grander D; Reed SI; Widschwendter M; Sangfelt O; Spruck C
    Cancer Res; 2007 Oct; 67(19):9006-12. PubMed ID: 17909001
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FBXW7: a critical tumor suppressor of human cancers.
    Yeh CH; Bellon M; Nicot C
    Mol Cancer; 2018 Aug; 17(1):115. PubMed ID: 30086763
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Systematic Discovery of FBXW7-Binding Phosphodegrons Highlights Mitogen-Activated Protein Kinases as Important Regulators of Intracellular Protein Levels.
    Singh N; Zeke A; Reményi A
    Int J Mol Sci; 2022 Mar; 23(6):. PubMed ID: 35328741
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Early growth response-1 is a new substrate of the GSK3β-FBXW7 axis.
    Yin L; Zhang J; Sun Y
    Neoplasia; 2022 Dec; 34():100839. PubMed ID: 36240645
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2.
    Jiménez-Izquierdo R; Morrugares R; Suanes-Cobos L; Correa-Sáez A; Garrido-Rodríguez M; Cerero-Tejero L; Khan OM; de la Luna S; Sancho R; Calzado MA
    Cell Death Dis; 2023 Mar; 14(3):202. PubMed ID: 36934104
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Distinct Interactions of EBP1 Isoforms with FBXW7 Elicits Different Functions in Cancer.
    Wang Y; Zhang P; Wang Y; Zhan P; Liu C; Mao JH; Wei G
    Cancer Res; 2017 Apr; 77(8):1983-1996. PubMed ID: 28209614
    [TBL] [Abstract][Full Text] [Related]  

  • 16. FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation.
    Babaei-Jadidi R; Li N; Saadeddin A; Spencer-Dene B; Jandke A; Muhammad B; Ibrahim EE; Muraleedharan R; Abuzinadah M; Davis H; Lewis A; Watson S; Behrens A; Tomlinson I; Nateri AS
    J Exp Med; 2011 Feb; 208(2):295-312. PubMed ID: 21282377
    [TBL] [Abstract][Full Text] [Related]  

  • 17. FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors.
    Jardim DL; Wheler JJ; Hess K; Tsimberidou AM; Zinner R; Janku F; Subbiah V; Naing A; Piha-Paul SA; Westin SN; Roy-Chowdhuri S; Meric-Bernstam F; Hong DS
    PLoS One; 2014; 9(2):e89388. PubMed ID: 24586741
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
    J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development.
    Davis H; Lewis A; Spencer-Dene B; Tateossian H; Stamp G; Behrens A; Tomlinson I
    J Pathol; 2011 Jun; 224(2):180-9. PubMed ID: 21503901
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SCF(FBXW7)-mediated degradation of p53 promotes cell recovery after UV-induced DNA damage.
    Galindo-Moreno M; Giráldez S; Limón-Mortés MC; Belmonte-Fernández A; Reed SI; Sáez C; Japón MÁ; Tortolero M; Romero F
    FASEB J; 2019 Oct; 33(10):11420-11430. PubMed ID: 31337255
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.