These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
196 related articles for article (PubMed ID: 38495100)
1. Neutrophil elastase as a versatile cleavage enzyme for activation of αvβ3 integrin-targeted small molecule drug conjugates with different payload classes in the tumor microenvironment. Rebstock AS; Wiedmann M; Stelte-Ludwig B; Wong H; Johnson AJ; Izumi R; Hamdy A; Lerchen HG Front Pharmacol; 2024; 15():1358393. PubMed ID: 38495100 [No Abstract] [Full Text] [Related]
2. Discovery of VIP236, an αvβ3-Targeted Small-Molecule-Drug Conjugate with Neutrophil Elastase-Mediated Activation of 7-Ethyl Camptothecin Payload for Treatment of Solid Tumors. Lerchen HG; Stelte-Ludwig B; Heroult M; Zubov D; Gericke KM; Wong H; Frigault MM; Johnson AJ; Izumi R; Hamdy A Cancers (Basel); 2023 Sep; 15(17):. PubMed ID: 37686656 [TBL] [Abstract][Full Text] [Related]
3. A Small Molecule-Drug Conjugate (SMDC) Consisting of a Modified Camptothecin Payload Linked to an α Lerchen HG; Stelte-Ludwig B; Kopitz C; Heroult M; Zubov D; Willuda J; Schlange T; Kahnert A; Wong H; Izumi R; Hamdy A Cancers (Basel); 2022 Jan; 14(2):. PubMed ID: 35053556 [TBL] [Abstract][Full Text] [Related]
4. Optimizing the enzymatic release of MMAE from Zambra M; Ranđelović I; Talarico F; Borbély A; Svajda L; Tóvári J; Mező G; Bodero L; Colombo S; Arrigoni F; Fasola E; Gazzola S; Piarulli U Front Pharmacol; 2023; 14():1215694. PubMed ID: 37492088 [TBL] [Abstract][Full Text] [Related]
5. In vivo activation of FAP-cleavable small molecule-drug conjugates for the targeted delivery of camptothecins and tubulin poisons to the tumor microenvironment. Bocci M; Zana A; Principi L; Lucaroni L; Prati L; Gilardoni E; Neri D; Cazzamalli S; Galbiati A J Control Release; 2024 Mar; 367():779-790. PubMed ID: 38346501 [TBL] [Abstract][Full Text] [Related]
6. Natural-source payloads used in the conjugated drugs architecture for cancer therapy: Recent advances and future directions. Li C; Shi K; Zhao S; Liu J; Zhai Q; Hou X; Xu J; Wang X; Liu J; Wu X; Fan W Pharmacol Res; 2024 Sep; 207():107341. PubMed ID: 39134188 [TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers. Dal Corso A; Caruso M; Belvisi L; Arosio D; Piarulli U; Albanese C; Gasparri F; Marsiglio A; Sola F; Troiani S; Valsasina B; Pignataro L; Donati D; Gennari C Chemistry; 2015 Apr; 21(18):6921-9. PubMed ID: 25784522 [TBL] [Abstract][Full Text] [Related]
8. Mono-amino acid linkers enable highly potent small molecule-drug conjugates by conditional release. Zheng Y; Xu R; Cheng H; Tai W Mol Ther; 2024 Apr; 32(4):1048-1060. PubMed ID: 38369752 [TBL] [Abstract][Full Text] [Related]
9. PSMA-targeted small-molecule drug-conjugates with valine-citrulline and phosphoramidate cleavable linkers. Savoy EA; Olatunji FP; Fulton MD; Kesic BN; Herman JW; Romero O; Maniatopoulos M; Berkman CE Bioorg Med Chem Lett; 2024 Jan; 98():129573. PubMed ID: 38052377 [TBL] [Abstract][Full Text] [Related]
10. Linker Architectures as Steric Auxiliaries for Altering Enzyme-Mediated Payload Release from Bioconjugates. Giese M; Davis PD; Woodman RH; Hermanson G; Pokora A; Vermillion M Bioconjug Chem; 2021 Oct; 32(10):2257-2267. PubMed ID: 34587447 [TBL] [Abstract][Full Text] [Related]
11. Dual intra- and extracellular release of monomethyl auristatin E from a neutrophil elastase-sensitive antibody-drug conjugate. Mohamed Amar IA; Huvelle S; Douez E; Letast S; Henrion S; Viaud-Massuard MC; Aubrey N; Allard-Vannier E; Joubert N; Denevault-Sabourin C Eur J Med Chem; 2022 Feb; 229():114063. PubMed ID: 34974337 [TBL] [Abstract][Full Text] [Related]
12. Small Molecule-Drug Conjugates: Opportunities for the Development of Targeted Anticancer Drugs. Zhang J; Hu F; Aras O; Chai Y; An F ChemMedChem; 2024 Jun; 19(11):e202300720. PubMed ID: 38396351 [TBL] [Abstract][Full Text] [Related]
13. Small molecule- and peptide-drug conjugates addressing integrins: A story of targeted cancer treatment. Paulus J; Sewald N J Pept Sci; 2024 Jul; 30(7):e3561. PubMed ID: 38382900 [TBL] [Abstract][Full Text] [Related]
14. Conjugates of Cryptophycin and RGD or Borbély A; Figueras E; Martins A; Bodero L; Raposo Moreira Dias A; López Rivas P; Pina A; Arosio D; Gallinari P; Frese M; Steinkühler C; Gennari C; Piarulli U; Sewald N ChemistryOpen; 2019 Jun; 8(6):737-742. PubMed ID: 31275795 [TBL] [Abstract][Full Text] [Related]
15. Tandem-Cleavage Linkers Improve the In Vivo Stability and Tolerability of Antibody-Drug Conjugates. Chuprakov S; Ogunkoya AO; Barfield RM; Bauzon M; Hickle C; Kim YC; Yeo D; Zhang F; Rabuka D; Drake PM Bioconjug Chem; 2021 Apr; 32(4):746-754. PubMed ID: 33689309 [TBL] [Abstract][Full Text] [Related]
16. Synthesis and Evaluation of a Non-Peptide Small-Molecule Drug Conjugate Targeting Integrin α Paulus J; Sewald N Front Chem; 2022; 10():869639. PubMed ID: 35480387 [TBL] [Abstract][Full Text] [Related]
17. Small molecule-drug conjugates: A novel strategy for cancer-targeted treatment. Zhuang C; Guan X; Ma H; Cong H; Zhang W; Miao Z Eur J Med Chem; 2019 Feb; 163():883-895. PubMed ID: 30580240 [TBL] [Abstract][Full Text] [Related]
18. αvβ3 Integrin-Targeted Peptide/Peptidomimetic-Drug Conjugates: In-Depth Analysis of the Linker Technology. Dal Corso A; Pignataro L; Belvisi L; Gennari C Curr Top Med Chem; 2016; 16(3):314-29. PubMed ID: 26126915 [TBL] [Abstract][Full Text] [Related]
19. Tailored Linker Chemistries for the Efficient and Selective Activation of ADCs with KSPi Payloads. Lerchen HG; Stelte-Ludwig B; Sommer A; Berndt S; Rebstock AS; Johannes S; Mahlert C; Greven S; Dietz L; Jörißen H Bioconjug Chem; 2020 Aug; 31(8):1893-1898. PubMed ID: 32667786 [TBL] [Abstract][Full Text] [Related]
20. Antibody drug conjugates beyond cytotoxic payloads. Hobson AD Prog Med Chem; 2023; 62():1-59. PubMed ID: 37981349 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]