141 related articles for article (PubMed ID: 38496463)
1. Efficient and multiplexed somatic genome editing with Cas12a mice.
Hebert JD; Xu H; Tang YJ; Ruiz PA; Detrick CR; Wang J; Hughes NW; Donosa O; Andrejka L; Karmakar S; Aboiralor I; Tang R; Sage J; Cong L; Petrov DA; Winslow MM
bioRxiv; 2024 May; ():. PubMed ID: 38496463
[TBL] [Abstract][Full Text] [Related]
2. Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.
Kleinstiver BP; Sousa AA; Walton RT; Tak YE; Hsu JY; Clement K; Welch MM; Horng JE; Malagon-Lopez J; Scarfò I; Maus MV; Pinello L; Aryee MJ; Joung JK
Nat Biotechnol; 2019 Mar; 37(3):276-282. PubMed ID: 30742127
[TBL] [Abstract][Full Text] [Related]
3. Multiplexed conditional genome editing with Cas12a in
Port F; Starostecka M; Boutros M
Proc Natl Acad Sci U S A; 2020 Sep; 117(37):22890-22899. PubMed ID: 32843348
[TBL] [Abstract][Full Text] [Related]
4. Enhanced mammalian genome editing by new Cas12a orthologs with optimized crRNA scaffolds.
Teng F; Li J; Cui T; Xu K; Guo L; Gao Q; Feng G; Chen C; Han D; Zhou Q; Li W
Genome Biol; 2019 Feb; 20(1):15. PubMed ID: 30717767
[TBL] [Abstract][Full Text] [Related]
5. Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates.
Ling X; Chang L; Chen H; Gao X; Yin J; Zuo Y; Huang Y; Zhang B; Hu J; Liu T
Mol Cell; 2021 Nov; 81(22):4747-4756.e7. PubMed ID: 34648747
[TBL] [Abstract][Full Text] [Related]
6. Engineered Cas12a-Plus nuclease enables gene editing with enhanced activity and specificity.
Huang H; Huang G; Tan Z; Hu Y; Shan L; Zhou J; Zhang X; Ma S; Lv W; Huang T; Liu Y; Wang D; Zhao X; Lin Y; Rong Z
BMC Biol; 2022 Apr; 20(1):91. PubMed ID: 35468792
[TBL] [Abstract][Full Text] [Related]
7. Highly specific chimeric DNA-RNA-guided genome editing with enhanced CRISPR-Cas12a system.
Kim H; Lee WJ; Kim CH; Oh Y; Gwon LW; Lee H; Song W; Hur JK; Lim KS; Jeong KJ; Nam KH; Won YS; Lee KR; Lee Y; Kim YH; Huh JW; Jun BH; Lee DS; Lee SH
Mol Ther Nucleic Acids; 2022 Jun; 28():353-362. PubMed ID: 35505967
[TBL] [Abstract][Full Text] [Related]
8. High-Throughput Profiling of Cas12a Orthologues and Engineered Variants for Enhanced Genome Editing Activity.
Zhu D; Wang J; Yang D; Xi J; Li J
Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948095
[TBL] [Abstract][Full Text] [Related]
9. Multiplexed activation in mammalian cells using a split-intein CRISPR/Cas12a based synthetic transcription factor.
Bryson JW; Auxillos JY; Rosser SJ
Nucleic Acids Res; 2022 Jan; 50(1):549-560. PubMed ID: 34908140
[TBL] [Abstract][Full Text] [Related]
10. Expanding the scope of plant genome engineering with Cas12a orthologs and highly multiplexable editing systems.
Zhang Y; Ren Q; Tang X; Liu S; Malzahn AA; Zhou J; Wang J; Yin D; Pan C; Yuan M; Huang L; Yang H; Zhao Y; Fang Q; Zheng X; Tian L; Cheng Y; Le Y; McCoy B; Franklin L; Selengut JD; Mount SM; Que Q; Zhang Y; Qi Y
Nat Commun; 2021 Mar; 12(1):1944. PubMed ID: 33782402
[TBL] [Abstract][Full Text] [Related]
11. Efficient Genome Editing in
An Y; Geng Y; Yao J; Fu C; Lu M; Wang C; Du J
Front Plant Sci; 2020; 11():593938. PubMed ID: 33329659
[TBL] [Abstract][Full Text] [Related]
12. Cas12a/Cpf1 knock-in mice enable efficient multiplexed immune cell engineering.
Dong MB; Tang K; Zhou X; Shen J; Chen K; Kim HR; Zhou J; Cao H; Vandenbulcke E; Zhang Y; Chow RD; Du A; Suzuki K; Fang SY; Majety M; Dai X; Chen S
bioRxiv; 2023 Mar; ():. PubMed ID: 36993642
[TBL] [Abstract][Full Text] [Related]
13. Implementing CRISPR-Cas12a for Efficient Genome Editing in Yarrowia lipolytica.
Yang Z; Xu P
Methods Mol Biol; 2021; 2307():111-121. PubMed ID: 33847985
[TBL] [Abstract][Full Text] [Related]
14. CRISPR/Cas12a Multiplex Genome Editing of Saccharomyces cerevisiae and the Creation of Yeast Pixel Art.
Ciurkot K; Vonk B; Gorochowski TE; Roubos JA; Verwaal R
J Vis Exp; 2019 May; (147):. PubMed ID: 31205318
[TBL] [Abstract][Full Text] [Related]
15. Assessment of Cas12a-mediated gene editing efficiency in plants.
Bernabé-Orts JM; Casas-Rodrigo I; Minguet EG; Landolfi V; Garcia-Carpintero V; Gianoglio S; Vázquez-Vilar M; Granell A; Orzaez D
Plant Biotechnol J; 2019 Oct; 17(10):1971-1984. PubMed ID: 30950179
[TBL] [Abstract][Full Text] [Related]
16. CRISPR-Cas12a/Cpf1-assisted precise, efficient and multiplexed genome-editing in
Yang Z; Edwards H; Xu P
Metab Eng Commun; 2020 Jun; 10():e00112. PubMed ID: 31867213
[TBL] [Abstract][Full Text] [Related]
17. Multiplexed genome regulation in vivo with hyper-efficient Cas12a.
Guo LY; Bian J; Davis AE; Liu P; Kempton HR; Zhang X; Chemparathy A; Gu B; Lin X; Rane DA; Xu X; Jamiolkowski RM; Hu Y; Wang S; Qi LS
Nat Cell Biol; 2022 Apr; 24(4):590-600. PubMed ID: 35414015
[TBL] [Abstract][Full Text] [Related]
18. Rational Design of Small Molecules to Enhance Genome Editing Efficiency by Selectively Targeting Distinct Functional States of CRISPR-Cas12a.
Li W; Chan C; Zeng C; Turk R; Behlke MA; Cheng X; Dong Y
Bioconjug Chem; 2020 Mar; 31(3):542-546. PubMed ID: 32119776
[TBL] [Abstract][Full Text] [Related]
19. Highly efficient and safe genome editing by CRISPR-Cas12a using CRISPR RNA with a ribosyl-2'-O-methylated uridinylate-rich 3'-overhang in mouse zygotes.
Ha DI; Lee JM; Lee NE; Kim D; Ko JH; Kim YS
Exp Mol Med; 2020 Nov; 52(11):1823-1830. PubMed ID: 33162553
[TBL] [Abstract][Full Text] [Related]
20. CRISPR-Cas12a has widespread off-target and dsDNA-nicking effects.
Murugan K; Seetharam AS; Severin AJ; Sashital DG
J Biol Chem; 2020 Apr; 295(17):5538-5553. PubMed ID: 32161115
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
