BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

121 related articles for article (PubMed ID: 38499151)

  • 1. Identification of PS1/gamma-secretase and glutamate transporter GLT-1 interaction sites.
    Perrin F; Sinha P; Mitchell SPC; Sadek M; Maesako M; Berezovska O
    J Biol Chem; 2024 Apr; 300(4):107172. PubMed ID: 38499151
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of PS1/gamma-secretase and glutamate transporter GLT-1 interaction sites.
    Perrin F; Sinha P; Mitchell S; Maesako M; Berezovska O
    bioRxiv; 2023 May; ():. PubMed ID: 37398024
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel interaction between Alzheimer's disease-related protein presenilin 1 and glutamate transporter 1.
    Zoltowska KM; Maesako M; Meier J; Berezovska O
    Sci Rep; 2018 Jun; 8(1):8718. PubMed ID: 29880815
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PS1/gamma-secretase acts as rogue chaperone of glutamate transporter EAAT2/GLT-1 in Alzheimer's disease.
    Perrin F; Anderson LC; Mitchell SPC; Sinha P; Turchyna Y; Maesako M; Houser MCQ; Zhang C; Wagner SL; Tanzi RE; Berezovska O
    Res Sq; 2023 Nov; ():. PubMed ID: 37986905
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ceftriaxone regulates glutamate production and vesicular assembly in presynaptic terminals through GLT-1 in APP/PS1 mice.
    Fan S; Li L; Xian X; Liu L; Gao J; Li W
    Neurobiol Learn Mem; 2021 Sep; 183():107480. PubMed ID: 34153453
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of new Presenilin-1 phosphosites: implication for γ-secretase activity and Aβ production.
    Matz A; Halamoda-Kenzaoui B; Hamelin R; Mosser S; Alattia JR; Dimitrov M; Moniatte M; Fraering PC
    J Neurochem; 2015 May; 133(3):409-21. PubMed ID: 25458374
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Conformational Models of APP Processing by Gamma Secretase Based on Analysis of Pathogenic Mutations.
    Kim M; Bezprozvanny I
    Int J Mol Sci; 2021 Dec; 22(24):. PubMed ID: 34948396
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dynamic Nature of presenilin1/γ-Secretase: Implication for Alzheimer's Disease Pathogenesis.
    Zoltowska KM; Berezovska O
    Mol Neurobiol; 2018 Mar; 55(3):2275-2284. PubMed ID: 28332150
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ceftriaxone Improves Cognitive Function and Upregulates GLT-1-Related Glutamate-Glutamine Cycle in APP/PS1 Mice.
    Fan S; Xian X; Li L; Yao X; Hu Y; Zhang M; Li W
    J Alzheimers Dis; 2018; 66(4):1731-1743. PubMed ID: 30452416
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dynamic presenilin 1 and synaptotagmin 1 interaction modulates exocytosis and amyloid β production.
    Zoltowska KM; Maesako M; Lushnikova I; Takeda S; Keller LJ; Skibo G; Hyman BT; Berezovska O
    Mol Neurodegener; 2017 Feb; 12(1):15. PubMed ID: 28193235
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of γ-Secretase Trimming Activity by Topological Changes of Transmembrane Domain 1 of Presenilin 1.
    Cai T; Yonaga M; Tomita T
    J Neurosci; 2017 Dec; 37(50):12272-12280. PubMed ID: 29118109
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ceftriaxone ameliorates hippocampal synapse loss by inhibiting microglial/macrophages activation in glial glutamate transporter-1 dependent manner in the APP/PS1 mouse model of Alzheimer's disease.
    Liu LZ; Fan SJ; Gao JX; Li WB; Xian XH
    Brain Res Bull; 2023 Aug; 200():110683. PubMed ID: 37301482
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Allosteric modulation of PS1/gamma-secretase conformation correlates with amyloid beta(42/40) ratio.
    Uemura K; Lill CM; Li X; Peters JA; Ivanov A; Fan Z; DeStrooper B; Bacskai BJ; Hyman BT; Berezovska O
    PLoS One; 2009 Nov; 4(11):e7893. PubMed ID: 19924286
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of gamma-secretase inhibitor potency determinants on presenilin.
    Zhao B; Yu M; Neitzel M; Marugg J; Jagodzinski J; Lee M; Hu K; Schenk D; Yednock T; Basi G
    J Biol Chem; 2008 Feb; 283(5):2927-38. PubMed ID: 18032377
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Quantitative comparison of presenilin protein expression reveals greater activity of PS2-γ-secretase.
    Eccles MK; Main N; Carlessi R; Armstrong AM; Sabale M; Roberts-Mok B; Tirnitz-Parker JEE; Agostino M; Groth D; Fraser PE; Verdile G
    FASEB J; 2024 Jan; 38(1):e23396. PubMed ID: 38156414
    [TBL] [Abstract][Full Text] [Related]  

  • 16. G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation.
    Chen WT; Hsieh YF; Huang YJ; Lin CC; Lin YT; Liu YC; Lien CC; Cheng IH
    Mol Neurobiol; 2015 Dec; 52(3):1835-1849. PubMed ID: 25394380
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Increased expression of PS1 is sufficient to elevate the level and activity of γ-secretase in vivo.
    Li T; Li YM; Ahn K; Price DL; Sisodia SS; Wong PC
    PLoS One; 2011; 6(11):e28179. PubMed ID: 22140537
    [TBL] [Abstract][Full Text] [Related]  

  • 18. GLT-1 loss accelerates cognitive deficit onset in an Alzheimer's disease animal model.
    Mookherjee P; Green PS; Watson GS; Marques MA; Tanaka K; Meeker KD; Meabon JS; Li N; Zhu P; Olson VG; Cook DG
    J Alzheimers Dis; 2011; 26(3):447-55. PubMed ID: 21677376
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alzheimer's disease-linked mutations in presenilin-1 result in a drastic loss of activity in purified γ-secretase complexes.
    Cacquevel M; Aeschbach L; Houacine J; Fraering PC
    PLoS One; 2012; 7(4):e35133. PubMed ID: 22529981
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rab21, a Novel PS1 Interactor, Regulates γ-Secretase Activity via PS1 Subcellular Distribution.
    Sun Z; Xie Y; Chen Y; Yang Q; Quan Z; Dai R; Qing H
    Mol Neurobiol; 2018 May; 55(5):3841-3855. PubMed ID: 28547526
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.