BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 38503282)

  • 1. Contrasting somatic mutation patterns in aging human neurons and oligodendrocytes.
    Ganz J; Luquette LJ; Bizzotto S; Miller MB; Zhou Z; Bohrson CL; Jin H; Tran AV; Viswanadham VV; McDonough G; Brown K; Chahine Y; Chhouk B; Galor A; Park PJ; Walsh CA
    Cell; 2024 Apr; 187(8):1955-1970.e23. PubMed ID: 38503282
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Contrasting patterns of somatic mutations in neurons and glia reveal differential predisposition to disease in the aging human brain.
    Ganz J; Luquette LJ; Bizzotto S; Bohrson CL; Jin H; Miller MB; Zhou Z; Galor A; Park PJ; Walsh CA
    bioRxiv; 2023 Jan; ():. PubMed ID: 36711756
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Single-neuron whole genome sequencing identifies increased somatic mutation burden in Alzheimer's disease related genes.
    Li Z; Min S; Alliey-Rodriguez N; Giase G; Cheng L; Craig DW; Faulkner GJ; Asif H; Liu C; Gershon ES
    Neurobiol Aging; 2023 Mar; 123():222-232. PubMed ID: 36599749
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genome aging: somatic mutation in the brain links age-related decline with disease and nominates pathogenic mechanisms.
    Lodato MA; Walsh CA
    Hum Mol Genet; 2019 Oct; 28(R2):R197-R206. PubMed ID: 31578549
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Pathological Endogenous α-Synuclein Accumulation in Oligodendrocyte Precursor Cells Potentially Induces Inclusions in Multiple System Atrophy.
    Kaji S; Maki T; Kinoshita H; Uemura N; Ayaki T; Kawamoto Y; Furuta T; Urushitani M; Hasegawa M; Kinoshita Y; Ono Y; Mao X; Quach TH; Iwai K; Dawson VL; Dawson TM; Takahashi R
    Stem Cell Reports; 2018 Feb; 10(2):356-365. PubMed ID: 29337114
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of somatic mutations in postmortem human brains by whole genome sequencing and their implications for psychiatric disorders.
    Nishioka M; Bundo M; Ueda J; Katsuoka F; Sato Y; Kuroki Y; Ishii T; Ukai W; Murayama S; Hashimoto E; Nagasaki M; Yasuda J; Kasai K; Kato T; Iwamoto K
    Psychiatry Clin Neurosci; 2018 Apr; 72(4):280-294. PubMed ID: 29283202
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements.
    Luquette LJ; Miller MB; Zhou Z; Bohrson CL; Zhao Y; Jin H; Gulhan D; Ganz J; Bizzotto S; Kirkham S; Hochepied T; Libert C; Galor A; Kim J; Lodato MA; Garaycoechea JI; Gawad C; West J; Walsh CA; Park PJ
    Nat Genet; 2022 Oct; 54(10):1564-1571. PubMed ID: 36163278
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity.
    Choudhury S; Huang AY; Kim J; Zhou Z; Morillo K; Maury EA; Tsai JW; Miller MB; Lodato MA; Araten S; Hilal N; Lee EA; Chen MH; Walsh CA
    Nat Aging; 2022 Aug; 2(8):714-725. PubMed ID: 36051457
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA damage in the oligodendrocyte lineage and its role in brain aging.
    Tse KH; Herrup K
    Mech Ageing Dev; 2017 Jan; 161(Pt A):37-50. PubMed ID: 27235538
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Monocarboxylate transporter 1 and the vulnerability of oligodendrocyte lineage cells to metabolic stresses.
    Zhou P; Guan T; Jiang Z; Namaka M; Huang QJ; Kong JM
    CNS Neurosci Ther; 2018 Feb; 24(2):126-134. PubMed ID: 29205833
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Demyelinating processes in aging and stroke in the central nervous system and the prospect of treatment strategy.
    Chen D; Huang Y; Shi Z; Li J; Zhang Y; Wang K; Smith AD; Gong Y; Gao Y
    CNS Neurosci Ther; 2020 Dec; 26(12):1219-1229. PubMed ID: 33210839
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular features driving cellular complexity of human brain evolution.
    Caglayan E; Ayhan F; Liu Y; Vollmer RM; Oh E; Sherwood CC; Preuss TM; Yi SV; Konopka G
    Nature; 2023 Aug; 620(7972):145-153. PubMed ID: 37468639
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Somatic cancer driver mutations are enriched and associated with inflammatory states in Alzheimer's disease microglia.
    Huang AY; Zhou Z; Talukdar M; Miller MB; Chhouk B; Enyenihi L; Rosen I; Stronge E; Zhao B; Kim D; Choi J; Khoshkhoo S; Kim J; Ganz J; Travaglini K; Gabitto M; Hodge R; Kaplan E; Lein E; De Jager PL; Bennett DA; Lee EA; Walsh CA
    bioRxiv; 2024 Jan; ():. PubMed ID: 38260600
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Common schizophrenia risk variants are enriched in open chromatin regions of human glutamatergic neurons.
    Hauberg ME; Creus-Muncunill J; Bendl J; Kozlenkov A; Zeng B; Corwin C; Chowdhury S; Kranz H; Hurd YL; Wegner M; Børglum AD; Dracheva S; Ehrlich ME; Fullard JF; Roussos P
    Nat Commun; 2020 Nov; 11(1):5581. PubMed ID: 33149216
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Many roles for oligodendrocyte precursor cells in physiology and pathology.
    Nishiyama A; Serwanski DR; Pfeiffer F
    Neuropathology; 2021 Jun; 41(3):161-173. PubMed ID: 33913208
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing.
    Rodin RE; Dou Y; Kwon M; Sherman MA; D'Gama AM; Doan RN; Rento LM; Girskis KM; Bohrson CL; Kim SN; Nadig A; Luquette LJ; Gulhan DC; ; Park PJ; Walsh CA
    Nat Neurosci; 2021 Feb; 24(2):176-185. PubMed ID: 33432195
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stalled oligodendrocyte differentiation in IDH-mutant gliomas.
    Wei Y; Li G; Feng J; Wu F; Zhao Z; Bao Z; Zhang W; Su X; Li J; Qi X; Duan Z; Zhang Y; Vega SF; Jakola AS; Sun Y; Carén H; Jiang T; Fan X
    Genome Med; 2023 Apr; 15(1):24. PubMed ID: 37055795
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhanced oligodendrocyte maturation and myelination in a mouse model of Timothy syndrome.
    Cheli VT; Santiago González DA; Zamora NN; Lama TN; Spreuer V; Rasmusson RL; Bett GC; Panagiotakos G; Paez PM
    Glia; 2018 Nov; 66(11):2324-2339. PubMed ID: 30151840
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Single-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespan.
    Zhang L; Dong X; Lee M; Maslov AY; Wang T; Vijg J
    Proc Natl Acad Sci U S A; 2019 Apr; 116(18):9014-9019. PubMed ID: 30992375
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Whole genome DNA sequencing provides an atlas of somatic mutagenesis in healthy human cells and identifies a tumor-prone cell type.
    Franco I; Helgadottir HT; Moggio A; Larsson M; Vrtačnik P; Johansson A; Norgren N; Lundin P; Mas-Ponte D; Nordström J; Lundgren T; Stenvinkel P; Wennberg L; Supek F; Eriksson M
    Genome Biol; 2019 Dec; 20(1):285. PubMed ID: 31849330
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.